Nurses with dermal exposure to antineoplastic drugs: Reproductive outcomes

Epidemiology

Volumn 18, Issue 1, 2007, Pages 112-119

  Fransman, Wouter ^a   Roeleveld, Nel ^b   Peelen, Susan ^a,b   De Kort, Wim ^c   Kromhout, Hans ^a   Heederik, Dick ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^c TNO   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CYCLOPHOSPHAMIDE;

ADULT; ARTICLE; CALCULATION; CONFIDENCE INTERVAL; CONGENITAL MALFORMATION; DRUG EXPOSURE; FEMALE; FERTILITY; HAZARD ASSESSMENT; HUMAN; LOGISTIC REGRESSION ANALYSIS; NURSE; OCCUPATIONAL EXPOSURE; ONCOLOGY; OUTCOME ASSESSMENT; PREGNANCY; PREMATURE LABOR; PRIORITY JOURNAL; QUESTIONNAIRE; REPRODUCTIVE HEALTH; RISK ASSESSMENT; SELF REPORT; SEX; SPONTANEOUS ABORTION; STILLBIRTH; SURVIVAL; TASK PERFORMANCE; TIME SERIES ANALYSIS;

ADULT; ANTINEOPLASTIC AGENTS; FEMALE; GLOVES, SURGICAL; HUMANS; INFERTILITY, FEMALE; NETHERLANDS; NURSES; OCCUPATIONAL EXPOSURE; PREGNANCY; PREGNANCY OUTCOME; SKIN ABSORPTION;

EID: 33845875482     PISSN: 10443983     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.ede.0000246827.44093.c1     Document Type: Article

References (31)

1. Sessink PJM, Boer KA, Scheefhals APH, et al. Occupational exposure to antineoplastic agents at several departments in a hospital. Environmental contamination and excretion of cyclophosphamide and ifosfamide in urine of exposed workers. Int Arch Occup Environ Health. 1992;64:105-112.
2. Sessink PJ, van de Kerkhof MC, Anzion RB, et al. Environmental contamination and assessment of exposure to antineoplastic agents by determination of cyclophosphamide in urine of exposed pharmacy technicians: is skin absorption an important exposure route? Arch Environ Health. 1994;49:165-169.
3. Ensslin AS, Stoll Y, Pethran A, et al. Biological monitoring of cyclophosphamide and ifosfamide in urine of hospital personnel occupationally exposed to cytostatic drugs. Occup Environ Med. 1994;51:229-233.
4. Kiffmeyer TK, Kube C, Opiolka S, et al. Vapour pressures, evaporation behaviour and airborne concentrations of hazardous drugs: implications for occupational safety. Pharm J. 2002;268:331-337.
5. Kromhout H, Hoek F, Uitterhoeve R, et al. Postulating a dermal pathway for exposure to anti-neoplastic drugs among hospital workers. Applying a conceptual model to the results of three workplace surveys. Ann Occup Hyg. 2000;44:551-560.
6. Fransman W, Vermeulen R, Kromhout H. Dermal exposure to cyclophosphamide in hospitals during preparation, nursing and cleaning activities. Int Arch Occup Environ Health. 2005;78:403-412.
7. Cardonick E, Iacobucci A. Use of chemotherapy during human pregnancy. Lancet Oncol. 2004;5:283-291.
8. Ebert U, Loffler H, Kirch W. Cytotoxic therapy and pregnancy. Pharmacol Ther. 1997;74:207-220.
9. Zemlickis D, Lishner M, Degendorfer P, et al. Fetal outcome after in utero exposure to cancer chemotherapy. Arch Intern Med. 1992;152:573-576.
10. Selevan SG, Lindbohm ML, Hornung RW, et al. A study of occupational exposure to antineoplastic drugs and fetal loss in nurses. N Engl J Med. 1985;313:1173-1178.
11. Stücker I, Caillard JF, Collin R, et al. Risk of spontaneous abortion among nurses handling antineoplastic drugs. Scand J Work Environ Health. 1990;16:102-107.
12. Stücker I, Mandereau L, Hémon D. Relationship between birthweight and occupational exposure to cytostatic drugs during or before pregnancy. Scand J Work Environ Health. 1993;19:148-153.
13. Valanis BG, Vollmer WM, Steele P. Occupational exposure to antineoplastic agents: self-reported miscarriages and stillbirths among nurses and pharmacists. J Occup Environ Med. 1999;41:632-638.
14. Hemminki K, Kyyronen P, Lindbohm ML. Spontaneous abortions and malformations in the offspring of nurses exposed to anaesthetic gases, cytostatic drugs, and other potential hazards in hospitals, based on registered information of outcome. J Epidemiol Community Health. 1985;39:141-147.
15. Skov T, Maarup B, Olsen JH, et al. Leukaemia and reproductive outcome among nurses handling antineoplastic drugs. Br J Ind Med. 1992;49:855-861.
16. Peelen S, Roeleveld N, Heederik D, et al. Reproductie-toxische effecten bij ziekenhuispersoneel. Den Haag, The Netherlands: Elsevier bedrijfsinformatie BV; 1999.
17. Weinberg CR, Baird DD, Wilcox AJ. Sources of bias in studies of time to pregnancy. Stat Med. 1994;13:671-681.
18. Hastie T, Tibshirani RJ. Generalized Additive Models, 1st ed. New York: Chapman & Hall; 1990.
19. Rothman K, Greenland S. Modern Epidemiology, 2nd ed. Philadelphia: Lippincott Williams & Wilkins; 1998.
20. Joffe M, Villard L, Li Z, et al. Long-term recall of time-to-pregnancy. Fertil Steril. 1993;60:99-104.
21. Baird DD, Weinberg CR, Rowland AS. Reporting errors in time-to-pregnancy data collected with a short questionnaire. Impact on power and estimation of fecundability ratios. Am J Epidemiol. 1991;133:1282-1290.
22. Joffe M, Villard L, Li Z, et al. A time to pregnancy questionnaire designed for long term recall: validity in Oxford, England. J Epidemiol Community Health. 1995;49:314-319.
23. Williams SF, Schilsky RL. Antineoplastic drugs administered during pregnancy. Semin Oncol. 2000;27:618-622.
24. Valanis BG, Vollmer WM, Labuhn KT, et al. Occupational exposure to antineoplastic agents and self-reported infertility among nurses and pharmacists. J Occup Environ Med. 1997;39:574-580.
25. Meijster T, Fransman W, van Hemmen JJ, et al. A probabilistic assessment of the impact of interventions on the exposure to antineoplastic agents of oncology nurses. Occup Environ Med. 2006;63:530-537.
26. NIOSH-Alert. Preventing occupational exposures to antineoplastic and other hazardous drugs in health care settings. Cincinatti. Available at: www.cdc.gov/niosh/docs/2004&cjs0025;165/pdfs/2004&cjs0025;165.pdf. 2004.
27. Hilhorst SKM, Miedema EP, Tijssen SCHA, et al. Blootstelling aan cytostatica in ziekenhuizen: Stand der techniek op het gebied van beheersmaatregelen. Den Haag, The Netherlands: Ministry of Social Affairs and Employment; 2001.
28. Ministry of Social Affairs and Employment. Arboconvenant academische ziekenhuizen. Den Haag, The Netherlands. Available at: www. arboconvenantacademischeziekenhuizen.nl/. 2004.
29. Health & Safety Executive. Safe handling of cytotoxic drugs. HSE Information Sheet MISC615. United Kingdom. Available at: www.hse.gov.uk/. 2003.
30. WorkSafe Victoria. Handling cytotoxic drugs in the workplace. Victoria, Australia. Available at: www.workcover.vic.gov.au/. 2003.
31. Sessink PJM, Scholtes MM, Anzion RBM, et al. Determination of cyclofosfamide in urine by gas chromatography-mass spectrometry. J Chromatogr B Biomed Appl. 1993;616:333-337.