Immune response to Leishmania (Leishmania) chagasi infection is reduced in malnourished BALB/c mice

Memorias do Instituto Oswaldo Cruz

Volumn 105, Issue 6, 2010, Pages 811-817

  Serafim, Tiago Donatelli ^a   Malafaia, Guilherme ^b   Silva, Marcelo Eustáquio ^a   Pedrosa, Maria Lúcia ^a   Rezende, Simone Aparecida ^a  

^a FEDERAL UNIVERSITY OF OURO PRETO   (Brazil)

^b Instituto Federal de Educacao   (Brazil)

Author keywords

BALB c; Interferon gamma; Interleukin 4; Leishmania chagasi; Malnutrition; Visceral leishmaniasis

Indexed keywords

ANIMALIA; LEISHMANIA DONOVANI CHAGASI; MURINAE; MUS;

EID: 77957973985     PISSN: 00740276     EISSN: 16788060     Source Type: Journal    
DOI: 10.1590/S0074-02762010000600014     Document Type: Article

References (40)

1. Afonso LC, Scott P 1993. Immune responses associated with susceptibility of C57BL/10 mice to Leishmania amazonensis. Infect Immun 61: 2952-2959.
2. Aguilar-Torrentera F, Carlier Y 2001. Immunological factors governing resistance and susceptibility of mice to Leishmania major infection. Rev Latinoam Microbiol 43: 135-142.
3. Anstead GM, Chandrasekar B, Zhao W, Yang J, Perez LE, Melby PC 2001. Malnutrition alters the innate immune response and increases early visceralization following Leishmania donovani infection. Infect Immun 69: 4709-4718.
4. Badaró R, Jones TC, Lorenço R, Cerf BJ, Sampaio D, Carvalho EM, Rocha H, Teixeira R, Johnson WD Jr 1986. A prospective study of visceral leishmaniasis in an endemic area of Brazil. J Infect Dis 154: 639-649.
5. Blössner M, Onis M 2005. Malnutrition: quantifying the health impact at national and local levels, World Health Organization, Geneva, p. 51.
6. Bouree P, Botterel F, Lancon A 2000. Study of protein profile in the visceral leishmaniasis. J Egypt Soc Parasitol 30: 885-893.
7. Caldas A, Favali C, Aquino D, Vinhas V, van Weyenbergh J, Brodskyn C, Costa J, Barral-Netto M, Barral A 2005. Balance of IL-10 and interferon-gamma plasma levels in human visceral leishmaniasis: implications in the pathogenesis. BMC Infect Dis 5: 113.
8. CCAC - Canadian Council on Animal Care 1980. Guide to the care and use of experimental animals. Available from: ccac.ca.
9. CCAC - Canadian Council on Animal Care 1984. Guide to the care and use of experimental animals. Available from: ccac.ca.
10. Carrión J, Nieto A, Iborra S, Iniesta V, Soto M, Folgueira C, Abanades DR, Requena JM, Alonso C 2006. Immunohistological features of visceral leishmaniasis in BALB/c mice. Parasite Immunol 28: 173-183.
11. Cerf BJ, Jones TC, Badaró R, Sampaio D, Teixeira R, Johnson WD Jr 1987. Malnutrition as a risk factor for severe visceral leishmaniasis. J Infect Dis 156: 1030-1033.
12. Chatraw JH, Wherry EJ, Ahmed R, Kapasi ZF 2008. Diminished primary CD8 T cell response to viral infection during protein energy malnutrition in mice is due to changes in microenvironment and low numbers of viral-specific CD8 T cell precursors. J Nutr 138: 806-812.
13. Cunningham-Rundles S, McNeeley DF, Moon A 2005. Mechanisms of nutrient modulation of the immune response. J Allergy Clin Immunol 115: 1119-1128.
14. Ekiz C, Agaoglu L, Karakas Z, Gurel N, Yalcin I 2005. The effect of iron deficiency anemia on the function of the immune system. Hematol J 5: 579-583.
15. Fock RA, Vinolo MA, Crisma AR, Nakajima K, Rogero MM, Borelli P 2008. Protein-energy malnutrition modifies the production of interleukin-10 in response to lipopolysaccharide (LPS) in a murine model. J Nutr Sci Vitaminol (Tokyo) 54: 371-377.
16. Garg R, Dube A 2006. Animal models for vaccine studies for visceral leishmaniasis. Indian J Med Res 123: 439-454.
17. Green LC, Wagner DA, Glogowski J, Skipper PL, Wishnok JS, Tannenbaum SR 1982. Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids. Anal Biochem 126: 131-138.
18. Ikeda S, Saito H, Fukatsu K, Inoue T, Han I, Furukawa S, Matsuda T, Hidemura A 2001. Dietary restriction impairs neutrophil exudation by reducing CD11b/CD18 expression and chemokine production. Arch Surg 136: 297-304.
19. Keusch GT 2003. The history of nutrition: malnutrition, infection and immunity. J Nutr 133: 336S-340S.
20. Lattime EC, Stoppacciaro A, Stutman O 1988. Limiting dilution analysis of TNF producing cells in C3H/HeJ mice. J Immunol 141: 3422-3428.
21. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ 1951. Protein measurement with the Folin phenol reagent. J Biol Chem 193: 265-275.
22. Maciel BL, Lacerda HG, Queiroz JW, Galvão J, Pontes NN, Dimenstein R, McGowan SE, Pedrosa LF, Jerônimo SM 2008. Association of nutritional status with the response to infection with Leishmania chagasi. Am J Trop Med Hyg 79: 591-598.
23. Malafaia G 2009. Protein-energy malnutrition as a risk factor for visceral leishmaniasis: a review. Parasite Immunol 31: 587-596.
24. Malafaia G, Serafim TD, Silva ME, Pedrosa ML, Rezende SA 2009. Protein-energy malnutrition decreases immune response to Leishmania chagasi vaccine in BALB/c mice. Parasite Immunol 31: 41-49.
25. Mansueto P, Vitale G, Di Lorenzo G, Rini GB, Mansueto S, Cillari E 2007. Immunopathology of leishmaniasis: an update. Int J Immunopathol Pharmacol 20: 435-445.
26. Marques-da-Silva EA, Coelho EA, Gomes DC, Vilela MC, Masioli CZ, Tavares CA, Fernandes AP, Afonso LC, Rezende SA 2005. Intramuscular immunization with p36(LACK) DNA vaccine induces IFN-gamma production but does not protect BALB/c mice against Leishmania chagasi intravenous challenge. Parasitol Res 98: 67-74.
27. Maurício IL, Stothard JR, Miles MA 2000. The strange case of Leishmania chagasi. Parasitol Today 16: 188-189.
28. McDade TW, Beck MA, Kuzawa CW, Adair LS 2001. Prenatal undernutrition and postnatal growth are associated with adolescent thymic function. J Nutr 131: 1225-1231.
29. McMurray DN 1981. Cellular immune changes in undernourished children. Prog Clin Biol Res 67: 305-318.
30. Melby PC, Chandrasekar B, Zhao W, Coe JE 2001. The hamster as a model of human visceral leishmaniasis: progressive disease and impaired generation of nitric oxide in the face of a prominent Th1-like cytokine response. J Immunol 166: 1912-1920.
31. Mukherjee P, Sen PC, Ghose AC 2006. Lymph node cells from BALB/c mice with chronic visceral leishmaniasis exhibiting cellular anergy and apoptosis: involvement of Ser/Thr phosphatase. Apoptosis 11: 2013-2029.
32. Nylén S, Sacks D 2007. Interleukin-10 and the pathogenesis of human visceral leishmaniasis. Trends Immunol 28: 378-384.
33. Oppenheimer SJ 2001. Iron and its relation to immunity and infectious disease. J Nutr 131: 616S-633S.
34. Prentice AM 1999. The thymus: a barometer of malnutrition. Br J Nutr 81: 345-347.
35. Raqib R, Roy SK, Rahman MJ, Azim T, Ameer SS, Chisti J, Andersson J 2004. Effect of zinc supplementation on immune and inflammatory responses in pediatric patients with shigellosis. Am J Clin Nutr 79: 444-450.
36. Reeves PG, Nielsen FH, Fahey GC Jr 1993. AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. J Nutr 123: 1939-1951.
37. Revillard JP, Cozon G 1991. Secondary deficiencies of humoral immunity. Rev Prat 41: 795-798.
38. Smelt SC, Engwerda CR, McCrossen M, Kaye PM 1997. Destruction of follicular dendritic cells during chronic visceral leishmaniasis. J Immunol 158: 3813-3821.
39. Titus RG, Marchand M, Boon T, Louis JA 1985. A limiting dilution assay for quantifying Leishmania major in tissues of infected mice. Parasite Immunol 7: 545-555.
40. Wilson ME, Streit JA 1996. Visceral leishmaniasis. Gastroenterol Clin North Am 25: 535-551.