Rapid and enhanced repolarization in sandwich-cultured hepatocytes on an oxygen-permeable membrane

Biochemical Engineering Journal

Volumn 52, Issue 2-3, 2010, Pages 255-262

  Matsui, Hitoshi ^a,b   Osada, Tomoharu ^b   Moroshita, Yasuyuki ^c   Sekijima, Masaru ^b   Fujii, Teruo ^a   Takeuchi, Shoji ^a   Sakai, Yasuyuki ^a  

^a INSTITUTE OF INDUSTRIAL SCIENCE   (Japan)

^b LSI MEDIENCE CORPORATION   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

Biliary excretion; Drug development; Hepatocyte; Oxygen permeable membrane; Polarity; Sandwich culture

Indexed keywords

BILIARY EXCRETION; DRUG DEVELOPMENT; HEPATOCYTES; POLARITY; SANDWICH CULTURE;

BIOCHEMISTRY; BODY FLUIDS; LIVING SYSTEMS STUDIES; MEMBRANES; MICROCHANNELS; OXYGEN; PHYSIOLOGY; POLYSTYRENES; SILICONES; TRANSMISSION ELECTRON MICROSCOPY;

OXYGEN PERMEABLE MEMBRANES;

CYTOCHROME P450; DIMETICONE; ETHOXYRESORUFIN; ETHOXYRESORUFIN DEETHYLASE; MULTIDRUG RESISTANCE PROTEIN 2; POLYSTYRENE;

ANIMAL CELL; ARTICLE; BILIARY EXCRETION; CONTROLLED STUDY; DEETHYLATION; DRUG METABOLISM; ENZYME ACTIVITY; IMMUNOHISTOCHEMISTRY; INTRAHEPATIC BILE DUCT; LIVER CELL; MEMBRANE; MICROVILLUS; MONOLAYER CULTURE; NONHUMAN; OXYGEN PERMEABLE MEMBRANE; OXYGEN TENSION; PRIORITY JOURNAL; RAT; TIGHT JUNCTION; TRANSMISSION ELECTRON MICROSCOPY;

RATTUS;

EID: 77957954435     PISSN: 1369703X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bej.2010.08.018     Document Type: Article

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