Implementation and experience of a web-based allocation system with Pocock and Simon's minimization methods

Contemporary Clinical Trials

Volumn 31, Issue 6, 2010, Pages 510-513

  Cai, Hong Wei ^a   Xia, Jie Lai ^a   Gao, Dong Huai ^a   Cao, Xiao Man ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Centralized randomization system; Dynamic randomization; Minimization; Web based

Indexed keywords

ARTICLE; CLINICAL RESEARCH; COMPUTER SYSTEM; INTERNET; METHODOLOGY; PATIENT SELECTION; RANDOMIZATION; TECHNIQUE;

ALGORITHMS; COMPUTER SECURITY; DOUBLE-BLIND METHOD; HUMANS; INTERNET; PATIENT DROPOUTS; PATIENT SELECTION; RANDOMIZED CONTROLLED TRIALS AS TOPIC; RESEARCH SUBJECTS; SOFTWARE;

EID: 77957952822     PISSN: 15517144     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cct.2010.07.009     Document Type: Article

References (13)

1. Lachin J.M., Matts J.P., Wei L.J. Randomization in clinical trials: conclusions and recommendations. Control Clin Trials 1988, 9(4):365-374.
2. Matts J.P., Lachin J.M. Properties of permuted-block randomization in clinical trials. Control Clin Trials 1988, 9(4):327-344.
3. Lachin J.M. Properties of simple randomization in clinical trials. Control Clin Trials 1988, 9(4):312-326.
4. Blair E. Gold is not always good enough: the shortcomings of randomization when evaluating interventions in small heterogeneous samples. J Clin Epidemiol 2004, 57(12):1219-1222.
5. Treasure T., MacRae K.D. Minimisation: the platinum standard for trials?. Randomisation doesn't guarantee similarity of groups; minimisation does. BMJ 1998, 317(7155):362-363.
6. Kernan W.N., Viscoli C.M., Makuch R.W., Brass L.M., Horwitz R.I. Stratified randomization for clinical trials. J Clin Epidemiol 1999, 52(1):19-26.
7. Pocock S.J., Simon R. Sequential treatment assignment with balancing for prognostic factors in the controlled clinical trial. Biometrics 1975, 31(1):103-115.
8. Scott N.W., McPherson G.C., Ramsay C.R., Campbell M.K. The method of minimization for allocation to clinical trials. a review. Control Clin Trials 2002, 23(6):662-674.
9. Stephen Evans, P.R.A.S., Accessed August 2, 2009. http://www-users.york.ac.uk/~mb55/guide/minim.htm.
10. Cai H., Xia J., Xu D., Gao D., Yan Y. A generic minimization random allocation and blinding system on web. J Biomed Inform 2006, 39(6):706-719.
11. Kenjo Y., Antoku Y., Akazawa K., Hanada E., Kinukawa N., Nose Y. An easily customized, random allocation system using the minimization method for multi-institutional clinical trials. Comput Meth Programs Biomed 2000, 62(1):45-49.
12. Brandt C.A., Morse R., Matthews K., Sun K., Deshpande A.M., Gadagkar R., et al. Metadata-driven creation of data marts from an EAV-modeled clinical research database. Int J Med Inform 2002, 65(3):225-241.
13. Effect of low-dose mobile versus traditional epidural techniques on mode of delivery: a randomised controlled trial. Lancet 2001, 358(9275):19-23.