Moringa oleifera prevents selenite-induced cataractogenesis in rat pups

Journal of Ocular Pharmacology and Therapeutics

Volumn 26, Issue 5, 2010, Pages 441-447

  Sasikala, V ^a   Rooban, B N ^a   Priya, S G Siva ^a   Sahasranamam, V ^b   Abraham, Annie ^a  

^a UNIVERSITY OF KERALA   (India)

^b Regional Institute of Ophthalmology   (India)

Author keywords

[No Author keywords available]

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; CATALASE; CATECHIN; FLAVONOID; GLUTATHIONE; MORINGA OLEIFERA EXTRACT; POLYPHENOL; QUERCETIN; REACTIVE OXYGEN METABOLITE; SODIUM SELENITE; SUPEROXIDE; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; THIOL DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CATARACT; CATARACTOGENESIS; CONTROLLED STUDY; ENZYME ACTIVITY; EYE PROTECTION; IC 50; LENS; LIPID PEROXIDATION; MORINGA OLEIFERA; NEWBORN; NONHUMAN; OXIDATIVE STRESS; PLANT LEAF; RAT;

ANIMALS; ANTIOXIDANTS; CATALASE; CATARACT; FLAVONOIDS; FREE RADICAL SCAVENGERS; GLUTATHIONE; GLUTATHIONE PEROXIDASE; LIPID PEROXIDATION; MORINGA OLEIFERA; OXIDATIVE STRESS; PHENOLS; PHYTOTHERAPY; PLANT LEAVES; PLANT PREPARATIONS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; SODIUM SELENITE; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCES;

EID: 77957951121     PISSN: 10807683     EISSN: None     Source Type: Journal    
DOI: 10.1089/jop.2010.0049     Document Type: Article

References (33)

1. Bockelbrink, A., Roll, S., Ruether, K., Rasch, A., Greiner, W., and Willich, S.N. Cataract surgery and the development or progression of age-related macular degeneration: a systematic review. Surv. Ophthalmol. 53:359-367, 2008.
2. Ostadalova, I., Babicky, A., and Obenberger, J. Cataract induced by administration of a single dose of sodium selenite to suckling rats. Experientia 34:222-223, 1978. (Pubitemid 8273945)
3. Shearer, T.R., Ma, H., Fukiage, C., and Azuma, M. Selenite nuclear cataract: review of the model. Mol. Vis. 3:8, 1997.
4. Hu, M.L., Louie, S., Cross, C.E., Motchink, P., and Halliwell, B. Antioxidant protection against hypochlorous acid in human plasma. J. Lab. Clin. Med. 121:257-262, 1992.
5. Rice-Evans, C.A., Miller, N.J., and Paganga, G. Structureantioxidant activity relationships of flavonoids and phenolic acids. Free Radic. Biol. Med. 20:933-956, 1996.
6. Kumar, N.A., and Pari, L. Antioxidant action of Moringa oleifera Lam. (drumstick) against antitubercular drugs induced lipid peroxidation in rats. J. Med. Food 6:255-259, 2003.
7. Morimitsu, Y., Hayashi, K., Nakagama, Y., Horio, F., Uchida, K., and Oswa, T. Antiplatelet and anticancer isothiocyanates in Japanese horseradish, wasabi. Biofactors 13: 271-276, 2000.
8. Siddhuraju, P., and Becker, K. Antioxidant properties of various solvent extracts of total phenolic constituents from three different agroclimatic origins of drumstick tree (Moringa oleifera Lam.) leaves. J. Agri. Food Chem. 51:2144-2155, 2003.
9. Anwar, F., Latif, S., Ashraf, M., and Gilani, A.H. Moringa oleifera: a food plant with multiple medicinal uses. Phytother. Res. 21:17-25, 2007.
10. Ragazzi, E., and Veronese, G. Quantitative analysis of phenolic compounds after thin layer chromatographic separation. J. Chromatogr. A 77:369-375, 1973.
11. Zhishen, J., Mengcheng, T., and Jianming, W. The determination of flavonoid content in mulberry and their scavenging effects on superoxide radicals. Food Chem. 64:555-559, 1999.
12. Molyneux, P. The use of the stable free radical diphenylpicrylhydrazyl (DPPH) for estimating antioxidant activity. Song. J. Sci. Technol. 26:211-219, 2004.
13. Fontana, M., Mosca, L., and Rosei, M.A. Interaction of enkephalines with oxyradicals. Biochem. Pharmacol. 61: 1253-1257, 2001.
14. Hiraoka, T., and Clark, J.I. Inhibition of lens opacification during the early stages of cataract formation. Invest. Ophthalmol. Vis. Sci. 36:2550-2555, 1995.
15. Davidson, J.F., Whyte, B., Bissinger, P.H., and Schiest, R.H. Oxidative stress is involved in heat-induced cell death in Saccharomyces cerevisiae. Proc. Natl. Accad. Sci. U. S. A. 93: 5116-5121, 1996.
16. Kakkar, P., Das, B., and Viswanathan, P.N. A modified spectrophotometric assay of superoxide dismutase. Indian J. Biochem. Biophys. 21:130-132, 1984.
17. Aebi, H. Catalase in vitro. Methods Enzymol. 105:121-126, 1984.
18. Sedlak, J., and Lindsay, R.H. Estimation of total, protein bound, and nonprotein sulfhydryl groups in tissue with Ellman's reagent. Anal. Biochem. 25:192-205, 1968.
19. Grattagliano, I., Vendemiale, G., Sabba, C., Buonamico, P., and Altomare, E. Oxidation of circulating proteins in alcoholics: role of acetaldehyde and xanthine oxidase. J. Hepatol. 25:28-36, 1996.
20. Niehaus, W.G., Jr., and Samuelsson, B. Formation of malonaldehyde from phospholipid arachidonate during microsomal lipid peroxidation. Eur. J. Biochem. 6:126-130, 1968.
21. Lowry, O.H., Rosebrough, N.J., Farr, A.L., and Randall, R.J. Protein measurement with the folin phenol reagent. J. Biol. Chem. 193:265-275, 1951.
22. Steel, R.G.D., Torrie, J.H., and Dickey, D.A. Principles and Procedures of Statistics. New York: McGraw Hill; 1996.
23. Siddhuraju, P., Mohan, P.S., and Becker, K. Studies on the antioxidant activity of Indian Laburnum (Cassia fistula L.): a preliminary assessment of crude extracts from stem bark, leaves, flowers and fruit pulp. Food Chem. 79:1-69, 2002
24. Varma, S.D., and Hegde, K.R. Effect of alpha-ketoglutarate against selenite cataract formation. Exp. EyeRes. 79:913-918, 2004.
25. Gupta, S.K., Srivastava, S., Trivedi, D., Joshi, S., and Halder, N. Ocimum sanctum modulates selenite-induced cataractogenic changes and prevents rat lens opacification. Curr. Eye Res. 30:583-591, 2005.
26. Lija, Y., Biju, P.G., Reeni, A., Cibin, T.R., Sahasranamam, V., and Abraham, A. Modulation of selenite cataract by the flavonoid fraction of Emilia sonchifolia in experimental animal models. Phytother. Res. 20:1091-1095, 2006.
27. Harding, J.J. Free and protein-bound glutathione in normal and cataractous human lenses. Biochem. J. 177:957-960, 1970.
28. Seko, Y., Saito, Y., Kitahara, J., and Imura, N. Active oxygen generation by the reaction of selenite with reduced glutathione in vitro. In: Wendel, A., ed. Selenium Biology and Medicine. New York: Springer-Verlag; 1989; pp. 70-73.
29. Harding, J.J. Can drugs or micronutrients prevent cataract. Drugs Aging 18:473-486, 2001.
30. Truscott, R.J.W., and Augusteyn, R.C. The state of sulphydryl groups in normal and cataractous human lenses. Exp. Eye Res. 25:139-148, 1977.
31. Rooban, B.N., Lija, Y., Biju, P.G., Sasikala, V., Sahasranamam, V., and Abraham, A. Vitex nigundo attenuates calpain activation and cataractogenesis in selenite models. Exp. Eye Res. 88:575-582, 2009.
32. Awasthi, S., Srivastava, S.K., Piper, J.T., Singhal, S.S., Chaubey, M., andAwasthi, Y.C. Curcumin protects against 4-hydroxy-2- noneal induced cataract. J. Clin. Nutr. 64:761-766, 1996.
33. Elanchezhian, R., Ramesh, E., Sakthivel, M., Isai, M., and Geraldine, P. Acetyl-L-carnitine prevents selenite-induced cataractogenesis in an experimental animal model. Curr. Eye Res. 32:961-971, 2007.