Use of a highly sensitive strand-specific quantitative PCR to identify abortive replication in the mouse model of respiratory syncytial virus disease

Virology Journal

Volumn 7, Issue , 2010, Pages

  Bannister, Richard ^a   Rodrigues, Deborah ^a   Murray, Edward J ^a   Laxton, Carl ^a   Westby, Mike ^a   Bright, Helen ^a  

^a PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

PALIVIZUMAB; RIBAVIRIN; VIRUS RNA;

ACCURACY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIVIRAL THERAPY; ARTICLE; BAGG ALBINO MOUSE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; INOCULATION; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; QUANTITATIVE ANALYSIS; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; RESPIRATORY SYNCYTIAL VIRUS INFECTION; RNA STRUCTURE; SINGLE DRUG DOSE; VIRUS CELL INTERACTION; VIRUS GENOME; VIRUS REPLICATION; ANIMAL; BIOSYNTHESIS; DISEASE MODEL; GENETICS; GROWTH, DEVELOPMENT AND AGING; LUNG; METHODOLOGY; PATHOGENICITY; VIROLOGY;

ANIMALIA; RESPIRATORY SYNCYTIAL VIRUS; RICE STRIPE VIRUS;

ANIMALS; DISEASE MODELS, ANIMAL; FEMALE; HUMANS; LUNG; MICE; MICE, INBRED BALB C; POLYMERASE CHAIN REACTION; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; RESPIRATORY SYNCYTIAL VIRUS, HUMAN; RNA, VIRAL; VIRUS REPLICATION;

EID: 77957951081     PISSN: None     EISSN: 1743422X     Source Type: Journal    
DOI: 10.1186/1743-422X-7-250     Document Type: Article

References (31)

1. Respiratory syncytial virus pneumonia among the elderly: an assessment of disease burden. LL Han JP Alexander LJ Anderson, J Infect Dis 1999 179 25 30 10.1086/314567 9841818
2. The outcome of 26 patients with respiratory syncytial virus infection following allogeneic stem cell transplantation. AJ McCarthy HM Kingman C Kelly GS Taylor EO Caul D Grier J Moppett AB Foot JM Cornish A Oakhill,, et al. Bone Marrow Transplant 1999 24 1315 1322 10.1038/sj.bmt.1702078 10627641
3. Impact of respiratory virus infections on persons with chronic underlying conditions. WP Glezen SB Greenberg RL Atmar PA Piedra RB Couch, Jama 2000 283 499 505 10.1001/jama.283.4.499 10659876
4. Recent trends in severe respiratory syncytial virus (RSV) among US infants, 1997 to 2000. S Leader K Kohlhase, J Pediatr 2003 143 127 132 14615711
5. Therapy of respiratory syncytial virus infection. JP DeVincenzo, Pediatr Infect Dis J 2000 19 786 790 discussion 802-784, 811-783 10959759
6. Respiratory syncytial virus prevention: past and present strategies. A Greenough M Thomas, Expert Opin Pharmacother 2000 1 1195 1201 10.1517/14656566.1.6.1195 11249487
7. Safety and pharmacokinetics of palivizumab therapy in children hospitalized with respiratory syncytial virus infection. X Saez-Llorens MT Moreno O Ramilo PJ Sanchez FH Top Jr EM Connor, Pediatr Infect Dis J 2004 23 707 712 10.1097/01.inf.0000133165.85909.08 15295219
8. Substituted benzimidazoles with nanomolar activity against respiratory syncytial virus. K Andries M Moeremans T Gevers R Willebrords C Sommen J Lacrampe F Janssens PR Wyde, Antiviral Res 2003 60 209 219 10.1016/j.antiviral. 2003.07.004 14638397
9. Inhibition of respiratory syncytial virus fusion by the small molecule VP-14637 via specific interactions with F protein. JL Douglas ML Panis E Ho KY Lin SH Krawczyk DM Grant R Cai S Swaminathan T Cihlar, J Virol 2003 77 5054 5064 10.1128/JVI.77.9.5054-5064.2003 12692208
10. Short duration aerosols of JNJ 2408068 (R170591) administered prophylactically or therapeutically protect cotton rats from experimental respiratory syncytial virus infection. PR Wyde SN Chetty P Timmerman BE Gilbert K Andries, Antiviral Res 2003 60 221 231 10.1016/j.antiviral.2003.07.002 14638398
11. Unravelling the complexities of respiratory syncytial virus RNA synthesis. VM Cowton DR McGivern R Fearns, J Gen Virol 2006 87 1805 1821 10.1099/vir.0.81786-0 16760383
12. Respiratory syncytial virus - viral biology and the host response. D Hacking J Hull, J Infect 2002 45 18 24 10.1053/jinf.2002.1015 12217726
13. Interactions between respiratory syncytial virus and the host cell: opportunities for antivirus strategies? RJ Sugrue, Expert Rev Mol Med 2006 8 1 17 10.1017/S1462399406000081 16953942
14. Animal models for studying respiratory syncytial virus infection and its long term effects on lung function. JB Domachowske CA Bonville HF Rosenberg, Pediatr Infect Dis J 2004 23 228 234 10.1097/01.inf.0000144672.81955.a4 15577578
15. Respiratory syncytial virus persistence in the lungs correlates with airway hyperreactivity in the mouse model. D Estripeaut JP Torres CS Somers C Tagliabue S Khokhar VG Bhoj SM Grube A Wozniakowski AM Gomez O Ramilo,, et al. J Infect Dis 2008 198 1435 1443 10.1086/592714 18828742
16. Respiratory syncytial virus infects and abortively replicates in the lungs in spite of preexisting immunity. MS Boukhvalova GA Prince JC Blanco, J Virol 2007 81 9443 9450 10.1128/JVI.00102-07 17596309
17. The cotton rat model of respiratory viral infections. MS Boukhvalova GA Prince JC Blanco, Biologicals 2009 37 152 159 10.1016/j.biologicals.2009.02.017 19394861
18. Respiratory syncytial virus infection in mice. G Taylor EJ Stott M Hughes AP Collins, Infect Immun 1984 43 649 655 6693171
19. Comparison of lung histopathology and bronchoalveolar lavage cytology in mice and cotton rats infected with respiratory syncytial virus. F Vaux-Peretz B Meignier, Vaccine 1990 8 543 548 10.1016/0264-410X(90)90005-7 2087875
20. Isolation and characterisation of potential respiratory syncytial virus receptor(s) on epithelial cells. R Malhotra M Ward H Bright R Priest MR Foster M Hurle E Blair M Bird, Microbes Infect 2003 5 123 133 10.1016/S1286-4579(02) 00079-5 12650770
21. Development of a Taqman RT-PCR assay for the detection and quantification of negatively stranded RNA of human enteroviruses: evidence for false-priming and improvement by tagged RT-PCR. M Bessaud A Autret S Jegouic J Balanant ML Joffret F Delpeyroux, J Virol Methods 2008 153 182 189 10.1016/j.jviromet.2008. 07.010 18706930
22. Respiratory syncytial virus-induced acute and chronic airway disease is independent of genetic background: an experimental murine model. S Chavez-Bueno A Mejias AM Gomez KD Olsen AM Rios M Fonseca-Aten O Ramilo HS Jafri, Virol J 2005 2 46 10.1186/1743-422X-2-46 15916706
23. Latency and persistence of respiratory syncytial virus despite T cell immunity. J Schwarze DR O'Donnell A Rohwedder PJ Openshaw, Am J Respir Crit Care Med 2004 169 801 805 10.1164/rccm.200308-1203OC 14742302
24. Respiratory syncytial virus, airway inflammation, and FEV1 decline in patients with chronic obstructive pulmonary disease. TM Wilkinson GC Donaldson SL Johnston PJ Openshaw JA Wedzicha, Am J Respir Crit Care Med 2006 173 871 876 10.1164/rccm.200509-1489OC 16456141
25. Detection of respiratory syncytial virus in adults with chronic obstructive pulmonary disease. AR Falsey MA Formica PA Hennessey MM Criddle WM Sullender EE Walsh, Am J Respir Crit Care Med 2006 173 639 643 10.1164/rccm.200510-1681OC 16387798
26. Respiratory syncytial virus persistence in chronic obstructive pulmonary disease. MB Sikkel JK Quint P Mallia JA Wedzicha SL Johnston, Pediatr Infect Dis J 2008 27 63 70 10.1097/INF.0b013e3181684d67 18820581
27. Respiratory syncytial virus infections: recent prospects for control. RW Sidwell DL Barnard, Antiviral Res 2006 71 379 390 10.1016/j.antiviral.2006.05. 014 16806515
28. Respiratory syncytial virus NS1 protein degrades STAT2 by using the Elongin-Cullin E3 ligase. J Elliott OT Lynch Y Suessmuth P Qian CR Boyd JF Burrows R Buick NJ Stevenson O Touzelet M Gadina,, et al. J Virol 2007 81 3428 3436 10.1128/JVI.02303-06 17251292
29. Interferon-mediated self-limiting growth of respiratory syncytial virus in mouse embryo cells. N Hanada T Morishima K Nishikawa S Isomura Y Nagai, J Med Virol 1986 20 363 370 10.1002/jmv.1890200409 2432168
30. Casein kinase 2-mediated phosphorylation of respiratory syncytial virus phosphoprotein P is essential for the transcription elongation activity of the viral polymerase; phosphorylation by casein kinase 1 occurs mainly at Ser(215) and is without effect. LC Dupuy S Dobson V Bitko S Barik, J Virol 1999 73 8384 8392 10482589
31. Species-specific restriction of apobec3-mediated hypermutation. EP Browne DR Littman, J Virol 2008 82 1305 1313 10.1128/JVI.01371-07 18032489