Ultrasonography criteria for differentiating ACTH dependency from ACTH independency in 47 dogs with hyperadrenocorticism and equivocal adrenal asymmetry

Journal of Veterinary Internal Medicine

Volumn 24, Issue 5, 2010, Pages 1077-1085

  Benchekroun, G ^a   de Fornel Thibaud, P ^a,b   Rodriguez Pineiro M I ^a,c   Rault, D ^a   Besso, J ^b   Cohen, A ^a   Hernandez, J ^a   Stambouli, F ^a   Gomes, E ^a   Garnier, F ^d   Begon, D ^a   Maurey Guenec, C ^a   Rosenberg, D ^a  

^a ECOLE NATIONALE VÉTÉRINAIRE D ALFORT   (France)

^b Veterinary Anticancer Center   (France)

^c UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

^d VETAGRO SUP   (France)

Author keywords

Adrenal gland; Asymmetry; Dog; Hyperadrenocorticism; Ultrasonography

Indexed keywords

CORTICOTROPIN; DEXAMETHASONE;

ADRENAL CORTEX HYPERFUNCTION; ADRENAL GLAND; ANIMAL; ANIMAL DISEASE; ARTICLE; DOG; DOG DISEASE; ECHOGRAPHY; METABOLISM; PATHOLOGY; RETROSPECTIVE STUDY;

ADRENAL GLANDS; ADRENOCORTICAL HYPERFUNCTION; ADRENOCORTICOTROPIC HORMONE; ANIMALS; DEXAMETHASONE; DOG DISEASES; DOGS; RETROSPECTIVE STUDIES;

ANIMALIA; CANIS FAMILIARIS;

EID: 77957919520     PISSN: 08916640     EISSN: 19391676     Source Type: Journal    
DOI: 10.1111/j.1939-1676.2010.0559.x     Document Type: Article

References (35)

1. Feldman EC, Nelson RW. Hyperadrenocorticism (Cushing's syndrome). In: Feldman EC, Nelson RW, eds. Canine and Feline Endocrinology and Reproduction. St Louis, MO: Saunders; 2004:252-357.
2. Peterson ME. Diagnosis of hyperadrenocorticism in dogs. Clin Tech Small Anim Pract 2007;22:2-11.
3. Behrend EN, Kemppainen RJ, Clark TP, et al. Diagnosis of hyperadrenocorticism in dogs: A survey of internists and dermatologists. J Am Vet Med Assoc 2002;220:1643-1649.
4. Gould SM, Baines EA, Mannion PA, et al. Use of endogenous ACTH concentration and adrenal ultrasonography to distinguish the cause of canine hyperadrenocorticism. J Small Anim Pract 2001;42:113-121.
5. Grooters AM, Biller DS, Theisen SK, Miyabayashi T. Ultrasonographic characteristics of the adrenal glands in dogs with pituitary-dependent hyperadrenocorticism: Comparison with normal dogs. J Vet Intern Med 1996;10:110-115.
6. Anderson CR, Birchard SJ, Powers BE, et al. Surgical treatment of adrenocortical tumors: 21 cases (1990-1996). J Am Anim Hosp Assoc 2001;37:93-97.
7. Besso JG, Penninck DG, Gliatto JM. Retrospective ultrasonographic evaluation of adrenal lesions in 26 dogs. Vet Radiol Ultrasound 1997;38:448-455.
8. Hoerauf A, Reusch CE. Ultrasonographic characteristics of both adrenal glands in 15 dogs with functional adrenocortical tumors. J Am Anim Hosp Assoc 1999;51:193-199.
9. Ginel PJ, Perez-Rico A, Moreno P, Lucena R. Validation of a commercially available enzyme-linked immunosorbent assay (ELISA) for the determination of cortisol in canine plasma samples. Vet Res Commun 1998;22:179-185.
10. Meijer JC, de Bruijne JJ, Rijnberk A, Croughs RJ. Biochemical characterization of pituitary-dependent hyperadrenocorticism in the dog. J Endocrinol 1978;77:111-118.
11. Meijer JC, Lubberink AA, Rijnberk A, Croughs RJ. Adrenocortical function tests in dogs with hyperfunctioning adrenocortical tumours. J Endocrinol 1979;80:315-319.
12. Feldman EC. Comparison of ACTH response and dexamethasone suppression as screening tests in canine hyperadrenocorticism. J Am Vet Med Assoc 1983;182:506-510.
13. Feldman EC, Nelson RW, Feldman MS. Use of low- and high-dose dexamethasone tests for distinguishing pituitary-dependent from adrenal tumor hyperadrenocorticism in dogs. J Am Vet Med Assoc 1996;209:772-775.
14. Granger N, de Fornel P, Devauchelle P, et al. Plasma proopiomelanocortin, pro-adrenocorticotropin hormone, and pituitary adenoma size in dogs with Cushing's disease. J Vet Intern Med 2005;19:23-28.
15. Scott-Moncrieff JC, Koshko MA, Brown JA, et al. Validation of a chemiluminescent enzyme immunometric assay for plasma adrenocorticotropic hormone in the dog. Vet Clin Pathol 2003;32: 180-187.
16. Rodríguez Piñeiro I, Benchekroun G, de Fornel-Thibaud P, et al. Accuracy of an ACTH immuno luminometric assay for differentiating ACTH-dependent from ACTH-independent hyperadrenocorticism in dogs. J Vet Intern Med 2009;23:850-855.
17. Grooters AM, Biller DS, Merryman J. Ultrasonographic parameters of normal canine adrenal glands: Comparison to necropsy findings. Vet Radiol Ultrasound 1995;36:126-130.
18. Tidwell AS, Penninck DG, Besso JG. Imaging of adrenal gland disorders. Vet Clin North Am Small Anim Pract 1997;27: 237-254.
19. Barthez PY, Nyland TG, Feldman EC. Ultrasonographic evaluation of the adrenal glands in dogs. J Am Vet Med Assoc 1995;207:1180-1183.
20. Churcher RK. Hepatic carcinoid, hypercortisolism and hypokalaemia in a dog. Aust Vet J 1999;77:641-645.
21. Galac S, Kooistra HS, Voorhout G, et al. Hyperadrenocorticism in a dog due to ectopic secretion of adrenocorticotropic hormone. Domest Anim Endocrinol 2005;28:338-348.
22. Galac S, Kars VJ, Voorhout G, et al. ACTH-independent hyperadrenocorticism due to food-dependent hypercortisolemia in a dog: A case report. Vet J 2008;177:141-143.
23. Newell-Price J, Trainer P, Besser M, Grossman A. The diagnosis and differential diagnosis of Cushing's syndrome and pseudo-Cushing's states. Endocr Rev 1998;19:647-672.
24. Boscaro M, Barzon L, Fallo F, Sonino N. Cushing's syndrome. Lancet 2001;357:783-791.
25. Greco DS, Peterson ME, Davidson AP, et al. Concurrent pituitary and adrenal tumors in dogs with hyperadrenocorticism: 17 cases (1978-1995). J Am Vet Med Assoc 1999;214:1349-1353.
26. Keiser M, Flückiger M, Gardelle O, Reusch CE. Mitotane treatment in a dog with a recurring adrenocortical carcinoma-a case report. Schweiz Arch Tierheilkd 1999;141:279-285.
27. Horauf A, Reusch C. Effects of mitotane therapy in dogs with pituitary dependent Cushing syndrome on the adrenal gland size-an ultrasonographic study. Schweiz Arch Tierheilkd 1999; 141:239-245.
28. Mantis P, Lamb CR, Witt AL, Neiger R. Changes in ultrasonographic appearance of adrenal glands in dogs with pituitarydependent hyperadrenocorticism treated with trilostane. Vet Radiol Ultrasound 2003;44:682-685.
29. Ruckstuhl NS, Nett CS, Reusch CE. Results of clinical examinations, laboratory tests, and ultrasonography in dogs with pituitary-dependent hyperadrenocorticism treated with trilostane. Am J Vet Res 2002;63:506-512.
30. Nyland TG, Mattoon JS, Herrgesell EJ, Wisner ER. Adrenal glands. In: Nyland TG, Mattoon JS, eds. Small Animal Diagnostic Ultrasound. Philadelphia, PA: WB Saunders Company; 2002:196-206.
31. Kantrowitz BM, Nyland TG, Feldman EC. Adrenal ultrasonography in the dog. Detection of tumors and hyperplasia in hyperadrenocorticism. Vet Radiol Ultrasound 1986;27:91-96.
32. Ford SL, Feldman EC, Nelson RW. Hyperadrenocorticism caused by bilateral adrenocortical neoplasia in dogs: Four cases (1983-1988). J Am Vet Med Assoc 1993;202:789-792.
33. Reusch CE, Feldman EC. Canine hyperadrenocorticism due to adrenocortical neoplasia. Pretreatment evaluation of 41 dogs. J Vet Intern Med 1991;5:3-10.
34. Orth DN, Kovacs WJ. The adrenal cortex. In: Wilson JD, Foster DW, Kronenberg HM, Larsen PR, eds. Williams Textbook of Endocrinology. Philadelphia, PA: WB Saunders; 1998:517-664.
35. Poffenbarger EM, Feeney DA, Hayden DW. Gray-scale ultrasonography in the diagnosis of adrenal neoplasia in dogs: Six cases (1981-1986). J Am Vet Med Assoc 1988;192:228-232.