The relationship of preconception thyrotropin levels to requirements for increasing the levothyroxine dose during pregnancy in women with primary hypothyroidism

Thyroid

Volumn 20, Issue 10, 2010, Pages 1175-1178

  Abalovich, Marcos ^a   Alcaraz, Graciela ^a   Kleiman Rubinsztein, Jessica ^a   Pavlove, María Magdalena ^a   Cornelio, Cecilia ^b   Levalle, Oscar ^a   Gutierrez, Silvia ^a  

^a HOSPITAL DURAND   (Argentina)

^b Hospital Pirovano   (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

LEVOTHYROXINE; THYROTROPIN; THYROXINE;

ADULT; ARTICLE; DRUG DOSE INCREASE; FEMALE; FREE THYROXINE INDEX; HUMAN; HYPOTHYROIDISM; MAJOR CLINICAL STUDY; PREGNANCY; PRENATAL PERIOD; PRIORITY JOURNAL; THYROTROPIN BLOOD LEVEL; THYROXINE BLOOD LEVEL;

ADULT; FEMALE; HUMANS; HYPOTHYROIDISM; PREGNANCY; PREGNANCY COMPLICATIONS; RETROSPECTIVE STUDIES; THYROTROPIN; THYROXINE;

EID: 77957889545     PISSN: 10507256     EISSN: None     Source Type: Journal    
DOI: 10.1089/thy.2009.0457     Document Type: Article

References (25)

1. Mandel SJ, Larsen PR, Seely EW, Brent GA 1990 Increased need for thyroxine during pregnancy in women with primary hypothyroidism. N Engl J Med 323:91-96.
2. Abalovich M, Gutierrez S, Alcaraz G, Maccallini G, Garcia A, Levalle O 2002 Overt and subclinical hypothyroidism complicating pregnancy. Thyroid 12:63-68.
3. Alexander EK, Marqusee E, Lawrence J, Jarolim P, Fischer GA, Larsen PR 2004 Timing and magnitude of increases in levothyroxine requirements during pregnancy in women with hypothyroidism. N Eng J Med 351:241-249.
4. Kaplan MM 1992 Monitoring thyroxine treatment during pregnancy. Thyroid 2:147-152.
5. Caixas A, Albareda M, Garcia-Patterson A, Rodriguez-Espinosa J, de Leiva A, Corcoy R 1999 Post partum thyroiditis in women with hypothyroidism antedating pregnancy. J Clin Endocrinol Metab 84:4000-4005.
6. Casey BM, Dashe JS, Wells CE, McIntire DD, Byrd W, Leveno KJ, Cunningham FG 2005 Subclinical hypothyroidism and pregnancy outcomes. Obstet Gynecol 105:239-245.
7. Stagnaro-Green A, Chen X, Bogden JD, Davies TF, Scholl TO 2005 The thyroid and pregnancy: a novel risk factor for very preterm delivery. Thyroid 15:351-357.
8. Leung AS, Millar LK, Koonings PP, Montoro M, Mestman JH 1993 Perinatal outcome in hypothyroid pregnancies. Obstet Gynecol 81:349-353.
9. Haddow JE, Palomaki GE, Allan WC, Williams JR, Knight GJ, Gagnon J, O'Heir CE, Mitchell ML, Hermos RJ, Waisbren SE, Faix JD, Klein RZ 1999 Maternal thyroid deficiency during pregnancy and subsequent neuropsychological development of the child. N Engl J Med 341:549-555.
10. Idris I, Srinivasan R, Simm A, Page R 2005 Maternal hypothyroidism in early and late gestation: effects on neonatal and obstetric outcome. Clin Endocrinol 63:560-565.
11. McClain MR, Lambert-Messerlian G, Haddow JE, Palomaski BS, Canick JA, Cleary-Goldman J, Malone FD, Flint Porter T, Nyberg DA, Bernstein P, D'Alton MA 2008 Sequential first and second trimester TSH, free thyroxine and thyroid antibody measurements in women with known hypothyroidism: a FaSTER trial study. Am J Obstet Gynecol 199:129.e1-129.e6.
12. Abalovich M, Amino N, Barbour LA, Cobin R, De Groot L, Glinoer D, Mandel S, Stagnaro-Green A 2007 Management of thyroid dysfunction during pregnancy and postpartum: an Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab 92: S1-S47.
13. Calvo R, Janiaux E, Gulbis B, Asuncion M, Gervy C, Contempre B, Morreale de Escobar M 2002 Fetal tissues are exposed to biologically relevant free thyroxine concentrations during early phases of development. J Clin Endocrinol Metab 87:1768-1777.
14. Glinoer D 1997 The regulation of thyroid function in pregnancy: pathways of endocrine adaptation from physiology to pathology. Endocr Rev 18:404-433.
15. Tamaki H, Amino N, Takeoka K, Mitsuda N, Miyai K, Tanizawa O 1990 Thyroxine requirements during pregnancy for replacement therapy of hypothyroidism. Obstet Gynecol 76:230-233.
16. Mc Dougall I, Maclin N 1995 Hypothyroid women need more thyroxine when pregnant. J Fam Pract 41:238-240.
17. Pekonen F, Teramo K, Ikonen E, Osterlund K, Makinen T, Lamberg BA 1984 Women on thyroid hormone therapy: pregnancy course, fetal outcome and amniotic fluid thyroid hormone level. Obstet Gynecol 63:635-638.
18. Girling JC, de Swiet M 1992 Thyroxine dosage during pregnancy in women with primary hypothyroidism. Br J Obstet Gynaecol 99:368-370.
19. Chopra IJ, Baber K 2003 Treatment of primary hypothyroidism during pregnancy: is there an increase in thyroxine dose requirement in pregnancy. Metabolism 52:122-128.
20. Kothari A, Girling J 2008 Hypothyroidism in pregnancy: pre-pregnancy thyroid status influences gestational thyroxine requirements. Br J Obstet Gynaecol 115:1704-1708.
21. Verga U, Bergamaschi S, Cortelazzi D, Ronzoni S, Marconi AM, Beck-Peccoz P 2009 Adjustment of L-T4 substitute therapy in pregnant women with subclinical, overt or postablative hypothyroidism. Clin Endocrinol 70:798-802.
22. Loh J, Wartofsky L, Jonklaas J, Burman K 2009 The magnitude of increased Levothyroxine requirements in hypothyroid pregnant women depends upon the etiology of the hypothyroidism. Thyroid 19:269-275.
23. Hallengren B, Lantz M, Andreasson B, Grennert L 2009 Pregnant women on thyroxine substitution are often dysregulated in early pregnancy. Thyroid 19:391-394.
24. Yassa L, Marqusee E, Fawcett R, Alexande EK 2010 Thyroid hormone early adjustment in pregnancy (the THERAPY) trial. J Clin Endocrinol Metab 95:3234-3241.
25. Rotondi M, Mazziotti G, Sorvillo F, Piscopo M, Cioffi M, Amato G, Carella C 2004 Effects of increased thyroxine dosage pre-conception on thyroid function during early pregnancy. Eur J Endocrinol 151:695-700.