SiRNA-mediated PIAS1 silencing promotes inflammatory response and leads to injury of cerulein-stimulated pancreatic acinar cells via regulation of the P38MAPK signaling pathway

International Journal of Molecular Medicine

Volumn 26, Issue 4, 2010, Pages 619-626

  Chen, Ping ^a   Huang, Liya ^a   Zhang, Yongping ^a   Qiao, Minmin ^a   Yuan, Yaozong ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Acinar cells; Apoptosis; Inflammation; Pancreas; Protein inhibitor of activated signal transducer and activator of transcription 1

Indexed keywords

BIOCHEMICAL MARKER; CASPASE 3; CERULETIDE; CYCLIN E; GELATINASE B; GENE PRODUCT; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P21; PROTEIN P27; PROTEIN P53; PROTEIN PIAS1; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ACINAR CELL; ACUTE PANCREATITIS; APOPTOSIS; ARTICLE; CELL CYCLE; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL CYCLE M PHASE; CELL DAMAGE; CONTROLLED STUDY; DETERIORATION; DISEASE SEVERITY; ENZYME ACTIVITY; GENE; GENE SILENCING; HUMAN; HUMAN CELL; INFLAMMATION; PIAS1 GENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

EID: 77957887430     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm_00000507     Document Type: Article

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