Relationships between levels of serum IgE, cell-bound IgE, and IgE-receptors on peripheral blood cells in a pediatric population

PLoS ONE

Volumn 5, Issue 8, 2010, Pages

  Dehlink, Eleonora ^a,b   Baker, Alexandra H ^a   Yen, Elizabeth ^a   Nurko, Samuel ^a   Fiebiger, Edda ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

CD123 ANTIGEN; CD14 ANTIGEN; CD23 ANTIGEN; GLYCOPROTEIN P 15095; IMMUNOGLOBULIN E; IMMUNOGLOBULIN E RECEPTOR; IMMUNOGLOBULIN FC FRAGMENT; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

ADOLESCENT; ADULT; AGE DISTRIBUTION; ANTIGEN BINDING; ANTIGEN EXPRESSION; ARTICLE; BASOPHIL; BINDING AFFINITY; CELL LEVEL; CELL SURFACE; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DENDRITIC CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOGLOBULIN BLOOD LEVEL; MALE; MONOCYTE; NEUTROPHIL; BLOOD; BLOOD CELL; GENE EXPRESSION REGULATION; INFANT; METABOLISM; PRESCHOOL CHILD;

ADOLESCENT; BLOOD CELLS; CHILD; CHILD, PRESCHOOL; FEMALE; GENE EXPRESSION REGULATION; HUMANS; IMMUNOGLOBULIN E; INFANT; MALE; MONOCYTES; RECEPTORS, IGE;

EID: 77957876670     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0012204     Document Type: Article

References (31)

1. Gould HJ, Sutton BJ (2008) IgE in allergy and asthma today. Nat Rev Immunol 8: 205-217.
2. Kraft S, Kinet JP (2007) New developments in FcepsilonRI regulation, function and inhibition. Nat Rev Immunol 7: 365-378.
3. Call ME, Wucherpfennig KW (2005) The T cell receptor: critical role of the membrane environment in receptor assembly and function. Annu Rev Immunol 23: 101-125.
4. Kubota T, Mukai K, Minegishi Y, Karasuyama H (2006) Different stabilities of the structurally related receptors for IgE and IgG on the cell surface are determined by length of the stalk region in their alpha-chains. J Immunol 176: 7008-7014.
5. Yamaguchi M, Sayama K, Yano K, Lantz CS, Noben-Trauth N, et al. (1999) IgE enhances Fc epsilon receptor I expression and IgE-dependent release of histamine and lipid mediators from human umbilical cord blood-derived mast cells: synergistic effect of IL-4 and IgE on human mast cell Fc epsilon receptor I expression and mediator release. J Immunol 162: 5455-5465.
6. Macglashan D, Jr. (2005) IgE and Fc{epsilon}RI regulation. Ann N Y Acad Sci 1050: 73-88.
7. Allam JP, Novak N, Fuchs C, Asen S, Berge S, et al. (2003) Characterization of dendritic cells from human oral mucosa: a new Langerhans' cell type with high constitutive FcepsilonRI expression. J Allergy Clin Immunol 112: 141-148.
8. Maurer D, Fiebiger E, Reininger B, Wolff-Winiski B, Jouvin MH, et al. (1994) Expression of functional high affinity immunoglobulin E receptors (Fc epsilon RI) on monocytes of atopic individuals. J Exp Med 179: 745-750.
9. Sihra BS, Kon OM, Grant JA, Kay AB (1997) Expression of high-affinity IgE receptors (Fc epsilon RI) on peripheral blood basophils, monocytes, and eosinophils in atopic and nonatopic subjects: relationship to total serum IgE concentrations. J Allergy Clin Immunol 99: 699-706.
10. Saini SS, Klion AD, Holland SM, Hamilton RG, Bochner BS, et al. (2000) The relationship between serum IgE and surface levels of FcepsilonR on human leukocytes in various diseases: correlation of expression with FcepsilonRI on basophils but not on monocytes or eosinophils. J Allergy Clin Immunol 106: 514-520.
11. Bieber T (1992) Fc epsilon RII/CD23 on epidermal Langerhans' cells. Res Immunol 143: 445-447.
12. Wollenberg A, Haberstok J, Teichmann B, Wen SP, Bieber T (1998) Demonstration of the low-affinity IgE receptor Fc epsilonRII/CD23 in psoriatic epidermis: inflammatory dendritic epidermal cells (IDEC) but not Langerhans cells are the relevant CD1a-positive cell population. Arch Dermatol Res 290: 517-521.
13. Lemieux GA, Blumenkron F, Yeung N, Zhou P, Williams J, et al. (2007) The low affinity IgE receptor (CD23) is cleaved by the metalloproteinase ADAM10. J Biol Chem 282: 14836-14844.
14. Weskamp G, Ford JW, Sturgill J, Martin S, Docherty AJ, et al. (2006) ADAM10 is a principal 'sheddase' of the low-affinity immunoglobulin E receptor CD23. Nat Immunol 7: 1293-1298.
15. Benhamou AH, Zamora SA, Eigenmann PA (2008) Correlation between specific immunoglobulin E levels and the severity of reactions in egg allergic patients. Pediatr Allergy Immunol 19: 173-179.
16. Celik-Bilgili S, Mehl A, Verstege A, Staden U, Nocon M, et al. (2005) The predictive value of specific immunoglobulin E levels in serum for the outcome of oral food challenges. Clin Exp Allergy 35: 268-273.
17. Rolinck-Werninghaus C, Keil T, Kopp M, Zielen S, Schauer U, et al. (2008) Specific IgE serum concentration is associated with symptom severity in children with seasonal allergic rhinitis. Allergy 63: 1339-1344.
18. Chehade M (2007) IgE and non-IgE-mediated food allergy: treatment in 2007. Curr Opin Allergy Clin Immunol 7: 264-268.
19. Novak N, Bieber T (2003) Allergic and nonallergic forms of atopic diseases. J Allergy Clin Immunol 112: 252-262.
20. Kjellman NM, Johansson SG, Roth A (1976) Serum IgE levels in healthy children quantified by a sandwich technique (PRIST). Clin Allergy 6: 51-59.
21. Wada T, Toma T, Shimura S, Kudo M, Kasahara Y, et al. (1999) Agedependent increase of IgE-binding and FcepsilonRI expression on circulating basophils in children. Pediatr Res 46: 603-607.
22. Conroy MC, Adkinson NF, Jr., lichtenstein LM (1977) Measurement of IgE on human basophils: relation to serum IgE and anti-IgE-induced histamine release. J Immunol 118: 1317-1321.
23. Malveaux FJ, Conroy MC, Adkinson NF, Jr., Lichtenstein LM (1978) IgE receptors on human basophils. Relationship to serum IgE concentration. J Clin Invest 62: 176-181.
24. Alphonse MP, Saffar AS, Shan L, HayGlass KT, Simons FE, et al. (2008) Regulation of the high affinity IgE receptor (Fc epsilonRI) in human neutrophils: role of seasonal allergen exposure and Th-2 cytokines. PLoS One 3: e1921.
25. Mora J, Riggs EK, Fu J, MacGlashan DW, Jr., Fox SA, et al. (2009) Expression of the high affinity IgE receptor by neutrophils of individuals with allergic asthma is both minimal and insensitive to regulation by serum IgE. Clin Immunol 132: 132-140.
26. Liang Y, Ganley-Leal LM (2009) A simple method for measuring human cellbound IgE levels in whole blood. J Immunol Methods.
27. Beck LA, Marcotte GV, MacGlashan D, Togias A, Saini S (2004) Omalizumabinduced reductions in mast cell Fce psilon RI expression and function. J Allergy Clin Immunol 114: 527-530.
28. Gomez G, Jogie-Brahim S, Shima M, Schwartz LB (2007) Omalizumab reverses the phenotypic and functional effects of IgE-enhanced Fc epsilonRI on human skin mast cells. J Immunol 179: 1353-1361.
29. Prussin C, Griffith DT, Boesel KM, Lin H, Foster B, et al. (2003) Omalizumab treatment downregulates dendritic cell FcepsilonRI expression. J Allergy Clin Immunol 112: 1147-1154.
30. Saini SS, MacGlashan DW, Jr., Sterbinsky SA, Togias A, Adelman DC, et al. (1999) Down-regulation of human basophil IgE and FC epsilon RI alpha surface densities and mediator release by anti-IgE-infusions is reversible in vitro and in vivo. J Immunol 162: 5624-5630.
31. Nopp A, Johansson SG, Ankerst J, Bylin G, Cardell LO, et al. (2006) Basophil allergen threshold sensitivity: a useful approach to anti-IgE treatment efficacy evaluation. Allergy 61: 298-302.