Interaction between organophosphate pesticide exposure and PON1 activity on thyroid function

Toxicology and Applied Pharmacology

Volumn 249, Issue 1, 2010, Pages 16-24

  Lacasaña, Marina ^a,b   López Flores, Inmaculada ^a,b   Rodríguez Barranco, Miguel ^a   Aguilar Garduño, Clemente ^a   Blanco Muñoz, Julia ^c   Pérez Méndez, Oscar ^d   Gamboa, Ricardo ^d   Gonzalez Alzaga, Beatriz ^a   Bassol, Susana ^e   Cebrian, Mariano E ^f  

^a ANDALUSIAN SCHOOL OF PUBLIC HEALTH   (Spain)

^b CIBER EPIDEMIOLOGÍA Y SALUD PÚBLICA CIBERESP   (Spain)

^c INSTITUTO NACIONAL DE SALUD PÚBLICA   (Mexico)

^d INSTITUTO NACIONAL DE CARDIOLOGÍA IGNACIO CHÁVEZ   (Mexico)

^e UNIVERSIDAD AUTÓNOMA DE COAHUILA   (Mexico)

^f DEPARTAMENTO DE FÍSICA   (Mexico)

Author keywords

Dialkylphosphates; Organophosphate pesticides; PON1 activity; PON1 polymorphisms; Thyroid hormone; TSH

Indexed keywords

ARYLDIALKYLPHOSPHATASE; ARYLDIALKYLPHOSPHATASE 1; ARYLESTERASE; DIAZOXONASE; ORGANOCHLORINE PESTICIDE; ORGANOPHOSPHATE PESTICIDE; THYROID HORMONE; THYROTROPIN; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; ORGANOPHOSPHORUS COMPOUND; PESTICIDE;

ADULT; ARTICLE; BLOOD SAMPLING; DNA POLYMORPHISM; ENZYME ACTIVITY; FLORICULTURE; GENETIC SUSCEPTIBILITY; HORMONE BLOOD LEVEL; HUMAN; MALE; OCCUPATIONAL EXPOSURE; STRUCTURED QUESTIONNAIRE; THYROID FUNCTION; URINALYSIS; AGRICULTURE; BLOOD; COMPARATIVE STUDY; DRUG EFFECTS; ENZYME ACTIVATION; ENZYMOLOGY; EPIDEMIOLOGY; FEMALE; GENETICS; LONGITUDINAL STUDY; METABOLISM; MEXICO; PHYSIOLOGY; THYROID FUNCTION TEST; THYROID GLAND; URINE; YOUNG ADULT;

ADULT; AGRICULTURE; ARYLDIALKYLPHOSPHATASE; BIOLOGICAL MARKERS; ENZYME ACTIVATION; FEMALE; HUMANS; LONGITUDINAL STUDIES; MALE; MEXICO; OCCUPATIONAL EXPOSURE; ORGANOPHOSPHORUS COMPOUNDS; PESTICIDES; THYROID FUNCTION TESTS; THYROID GLAND; THYROTROPIN; YOUNG ADULT;

EID: 77957861660     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2010.07.024     Document Type: Article

References (38)

1. Bjørling-Poulsen M., Andersen H.R., Grandjean P. Potential developmental neurotoxicity of pesticides used in Europe. Environ. Health 2008, 7:50.
2. Bouvier G., Seta N., Vigouroux-Villard A., Blanchard O., Momas I. Insecticide urinary metabolites in nonoccupationally exposed populations. J. Toxicol. Environ. Health B 2005, 8:485-512.
3. Bradman A., Whitaker D., Quirós L., Castorina R., Henn B.C., Nishioka M., Morgan J., Barr D.B., Harnly M., Brisbin J.A., Sheldon L.S., McKone T.E., Eskenazi B. Pesticides and their metabolites in the homes and urine of farmworker children living in the Salinas Valley, CA. J. Exposure Sci. Environ. Epidemiol. 2007, 17:331-349.
4. Brophy V.H., Jampsa R.L., Clendenning J.B., McKinstry L.A., Jarvik G.P., Furlong C.E. Effects of 5' regulatory-region polymorphisms on paraoxonase-gen (PON1) expression. Am. J. Hum. Genet. 2001, 68:1428-1436.
5. Browne R.O., Moyal-Segal L.B., Zumsteg D., David Y., Kofman O., Berger A., Soreq H., Friedman A. Coding region paraoxonase polymorphisms dictate accentuated neuronal reactions in chronic, sub-threshold pesticide exposure. FASEB J. 2006, 20:1733-1735.
6. CDC. Third National Report on Human Exposure to Environmental Chemicals 1999-2002, CDC, Centers for Disease Control and Prevention, Washington, DC, http://www.cdc.gov/exposurereport/results_09.htm.
7. Chiamolera M.I., Wondisford F.E. Minireview: thyrotropin-releasing hormone and the thyroid hormone feedback mechanism. Endocrinology 2009, 150:1091-1096.
8. Cocker J., Manson H.J., Garfitt S.J., Jones K. Biological monitoring of exposure to organophosphate pesticides. Toxicol. Lett. 2002, 134:97-103.
9. Cole T.B., Walter B.J., Shih D.M., Tward A.D., Lusis A.J., Timchalk C., Richter R.J., Costa L.G., Furlong C.E. Toxicity of chlorpyrifos and chlorpyrifos oxon in a transgenic mouse model of the human paraoxonase (PON1) Q192R polymorphism. Pharmacogenet. Genomics 2005, 15:589-598.
10. Costa L.G., Richter R.J., Li W.F., Cole T., Guizzetti M., Furlong C.E. Paraoxonase (PON1) as a biomarker of susceptibility for organophosphate toxicity. Biomarkers 2003, 8:1-12.
11. Costa L.G., Cole T.B., Vitalone A., Furlong C.E. Measurement of paraoxonase (PON1) status as a potential biomarker of susceptibility to organophosphate toxicity. Clin. Chim. Acta 2005, 352:37-47.
12. Costa L.G., Vitalone A., Cole T.B., Furlong C.E. Modulation of paraoxonase (PON1) activity. Biochem. Pharmacol. 2005, 69:541-550.
13. Davies H., Richter R.J., Kiefer M., Broomfield C., Sowalla J., Furlong C. The effect of the human serum paraoxonase polymorphism is reversed with diazoxon, soman and sarin. Nat. Genet. 1996, 14:334-336.
14. Fenske R.A., Bradman A., Whyatt R.M., Wolff M.S., Barr D.B. Lessons learned for the assessment of children's pesticide exposure: critical sampling and analytical issues for future studies. Environ. Health Perspect. 2005, 113:1455-1462.
15. Hagmar L., Bjork J., Sjodin A., Bergman A., Erfurth E.M. Plasma levels of persistent organohalogens and hormone levels in adult male humans. Arch. Environ. Health 2001, 56:138-143.
16. Hernández A., López O., Rodrigo L., Gil F., Pena G., Serrano J.L., Parrón T., Álvarez J.C., Lorente J.A., Pla A. Changes in erythrocyte enzymes in humans long-term exposed to pesticides. Influence of several markers of individual susceptibility. Toxicol. Lett. 2005, 159:13-21.
17. International Council for the Control of Iodine Deficiency Disorders 2010, ICCIDD, http://www.iccidd.org.
18. Lacasaña M., López-Flores I., Rodríguez-Barranco M., Aguilar-Garduño C., Blanco-Muñoz J., Pérez-Méndez O., Gamboa R., Bassol S., Cebrián M.E. Association between organophosphate pesticides exposure and thyroid hormones in floriculture workers. Toxicol. Appl. Pharmacol. 2010, 243:19-26.
19. Li W.F., Costa L.G., Richter R.J., Hagen T., Shih D.M., Tward A., Lusis A.J., Furlong C.E. Catalytic efficiency determines the in vivo efficacy of PON1 in detoxifying organophosphate. Pharmacogenetics 2000, 10:767-780.
20. López-Espinosa M.J., Vizcaino E., Murcia M., Llop S., Espada M., Seco V., Marco A., Rebagliato M., Grimalt J.O., Ballester F. Association between thyroid hormone levels and 4, 4-DDE concentrations in pregnant women (Valencia, Spain). Environ. Res. 2009, 109:479-485.
21. López-Flores I., Lacasaña M., Blanco-Muñoz J., Aguilar-Garduño C., Sánchez-Villegas P., Pérez-Méndez O.A., Gamboa-Ávila R. Relationship between human paraoxonase-1 activity and PON1 polymorphisms in Mexican workers exposed to organophosphate pesticides. Toxicol. Lett. 2009, 188:84-90.
22. Lu C., Fenske R.A., Simcox N.J., Kalman D. Pesticide exposure of children in an agricultural community: evidence of household proximity to farmland and take home exposure pathways. Environ. Res. 2000, 84:290-302.
23. Meeker J.D., Barr D.B., Hauser R. Thyroid hormones in relation to urinary metabolites of non-persistent insecticides in men of reproductive age. Reprod. Toxicol. 2005, 22:437-442.
24. Meeker J.D., Barr D.B., Ryan L., Altshul L. Temporal variability of urinary levels of non persistent insecticides in adult men. J. Expo. Anal. Environ. Epidemiol. 2005, 15:271-281.
25. Meeker J.D., Altshul L., Hauser R. Serum PCBs, p,p'-DDE and HCB predict thyroid hormone levels in men. Environ. Res. 2007, 104:296-304.
26. Persky V., Turyk M., Anderson H.A., Hanrahan L.P., Falk C., Steenport D.N., Chatterton R., Freels S. The effects of PCB exposure and fish consumption on endogenous hormones. Environ. Health Perspect. 2001, 109:1275-1283. Great Lakes Consortium.
27. Sirivarasai J., Kaojarern S., Yoovathaworn K., Sura T. Paraoxonase (PON1) polymorphism and activity as the determinants of sensitivity to organophosphates in human subjects. Chem. Biol. Interact. 2007, 168:184-192.
28. Takser L., Mergler D., Baldwin M., de Grosbois S., Smargiassi A., Lafond J. Thyroid hormones in pregnancy in relation to environmental exposure to organochlorine compounds and mercury. Environ. Health Perspect. 2005, 113:1039-1045.
29. Toft G., Flyvbjerg A., Bonde J.P. Thyroid function in Danish greenhouse workers. Environ. Health 2006, 5:32.
30. Torres-Sánchez L., Rothenberg S.J., Schnass L., Cebrián M.E., Osorio E., Hernández M.C., García-Hernández R.M., del Rio-García C., Wolff M.S., López-Carrillo L. In utero p, p'-DDE exposure and infant neurodevelopment: a perinatal cohort in Mexico. Environ. Health Perspect. 2007, 115:435-439.
31. Turyk M.E., Anderson H.A., Persky V.W. Relationships of thyroid hormones with polychlorinated biphenyls, dioxins, furans and DDE in adults. Environ. Health Perspect. 2007, 115:1197-1203.
32. Ueyama J., Saito I., Kamijima M., Nakajima T., Gotoh M., Suzuki T., Shibata E., Kondo T., Takagi K., Miyamoto K., Takamatsu J., Hasegawa T., Takagi K. Simultaneous determination of urinary dialkylphosphate metabolites of organophosphorous pesticides using gas chromatography-mass spectrometry. J. Chromatogr. B. 2006, 832:58-66.
33. Watts R., Lewis R.G., Moseman R.F., Hodgson D.W., Sherma J., Beroza M. Analysis of Pesticide Residues in Human and Environmental Samples. A Compilation of Methods Selected for Use in Pesticide Monitoring Programs 1980, U.S. Environmental Protection Agency, Health Effects Research Laboratory, Research Triangle Park; NC.
34. WHO special programme of research development and training in human reproduction. Programme for the Provision of Matched Assay Reagents for the Immunoassay and Radioimmunoassay of Hormones, 1999 1999, WHO, World Health Organization, Geneva.
35. Yánez L., Borja-Aburto V.H., Rojas E., de la Fuente H., González-Amaro R., Gómez H., Longitud A.A., Díaz-Barriga F. DDT induces DNA damage in blood cells. Studies in vitro and in women chronically exposed to this insecticide. Environ. Res. 2000, 94:18-24.
36. Zaidi S.A., Bhatnagar V.K., Gandhi S.J., Shah M.P., Kulkarni P.K., Saiyed H.N. Assessment of thyroid function in pesticide formulators. Hum. Exp. Toxicol. 2000, 19:497-501.
37. Zaidi S., Tiwari R., Gandhi S., Patel K., Kumar S., Saiyed H. Neurobehavioral effects and hormones profile among spray painters. Ind. Health 2006, 44:93-97.
38. Zollner N., Kirsch K. Microdetermination of lipids by the sulphophosphovanillin reaction. Z. Ges. Exp. Med. 1962, 135:545-561.