The cystatin M/E-cathepsin L balance is essential for tissue homeostasis in epidermis, hair follicles, and cornea

FASEB Journal

Volumn 24, Issue 10, 2010, Pages 3744-3755

  Zeeuwen, Patrick L J M ^a   Van Vlijmen Willems, Ivonne M J J ^a   Cheng, Tsing ^a   Rodijk Olthuis, Diana ^a   Hitomi, Kiyotaka ^c   Hara Nishimura, Ikuko ^d   John, Susan ^e   Smyth, Neil ^e   Reinheckel, Thomas ^f   Hendriks, Wiljan J A J ^b   Schalkwijk, Joost ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^c NAGOYA UNIVERSITY   (Japan)

^d KYOTO UNIVERSITY   (Japan)

^e UNIVERSITY OF COLOGNE   (Germany)

^f UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Differentiation; Mouse models; Proteases; Skin barrier; Transglutaminases

Indexed keywords

CATHEPSIN L; CYSTATIN M; LEGUMAIN; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE 3; PROTEINASE; UNCLASSIFIED DRUG; CST6 PROTEIN, MOUSE; CTSL PROTEIN, MOUSE; CYSTEINE PROTEINASE; PRIMER DNA;

ALOPECIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL VIABILITY; CORNEA EPITHELIUM; CYTOLOGY; ENZYME ACTIVATION; EPIDERMIS; EPITHELIUM HYPERPLASIA; HAIR FOLLICLE; HOMEOSTASIS; KERATITIS; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN FUNCTION; SQUAMOUS CELL METAPLASIA; STRATUM CORNEUM; ANIMAL; C57BL MOUSE; CORNEA; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; HAIR; KNOCKOUT MOUSE; METABOLISM; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALIA; MUS;

ANIMALS; BASE SEQUENCE; BLOTTING, WESTERN; CATHEPSIN L; CORNEA; CYSTATIN M; CYSTEINE ENDOPEPTIDASES; DNA PRIMERS; EPIDERMIS; FLUORESCENT ANTIBODY TECHNIQUE; HAIR; HOMEOSTASIS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; POLYMERASE CHAIN REACTION;

EID: 77957854397     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.10-155879     Document Type: Article

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