Metalcarbonyl complexes of acetylsalicylic acid as neo-anticancer agents

European Journal of Medicinal Chemistry

Volumn 45, Issue 11, 2010, Pages 5157-5163

  Rubner, Gerhard ^a   Bensdorf, Kerstin ^a   Wellner, Anja ^a   Bergemann, Silke ^a   Ott, Ingo ^b   Gust, Ronald ^a,c  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

^b TECHNICAL UNIVERSITY OF BRAUNSCHWEIG   (Germany)

^c UNIVERSITY OF INNSBRUCK   (Austria)

Author keywords

Acetylsalicylic acid; COX inhibition; Cyclopentadiene; Cytotoxicity; Transition metal complexes

Indexed keywords

2 (CYCLOPENTA 1,3 DIENYL)ETHYL 2 ACETOXYBENZOATE; 3 (CYCLOPENTA 1,3 DIENYL)PROPYL 2 ACETOXYBENZOATE; 4 (CYCLOPENTA 1,3 DIENYL)BUTYL 2 ACETOXYBENZOATE; ACETYLSALICYLIC ACID; ANTINEOPLASTIC METAL COMPLEX; CISPLATIN; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; ETA 5 [3 ((CYCLOPENTADIENYL)PROPYL) 2 ACETOXYBENZOATE]DICARBONYLCOBALT; ETA 5 [3 ((CYCLOPENTADIENYL)PROPYL) 2 ACETOXYBENZOATE]DICARBONYLRHODIUM; ETA 5 [3 ((CYCLOPENTADIENYL)PROPYL) 2 ACETOXYBENZOATE]IODOTRICARBONYLMOLYBDENUM; ETA 5 [3 ((CYCLOPENTADIENYL)PROPYL) 2 ACETOXYBENZOATE]THALLIUM; ETA 5 [3 ((CYCLOPENTADIENYL)PROPYL) 2 ACETOXYBENZOATE]TRICARBONYLMANGANESE; ETA 5 [3 ((CYCLOPENTADIENYL)PROPYL) 2 ACETOXYBENZOATE]TRICARBONYLMOLYBDENUM; PROSTAGLANDIN E2; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; CYCLOPENTANE DERIVATIVE; PROSTAGLANDIN SYNTHASE INHIBITOR;

ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER INHIBITION; CARCINOMA CELL; CELL STRAIN HT29; CELL STRAIN MCF 7; COLON CANCER; CONTROLLED STUDY; CYTOTOXICITY; ENZYME INHIBITION; ENZYME ISOLATION; HUMAN; HUMAN CELL; TUMOR GROWTH; CHEMISTRY; DRUG EFFECT; DRUG SCREENING; ELECTROSPRAY MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; STRUCTURE ACTIVITY RELATION; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; ASPIRIN; CELL LINE, TUMOR; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE INHIBITORS; CYCLOPENTANES; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 77957845237     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2010.08.028     Document Type: Article

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