Synthesis of new pyrazole derivatives and their anticancer evaluation

European Journal of Medicinal Chemistry

Volumn 45, Issue 11, 2010, Pages 4914-4919

  Nitulescu, George Mihai ^a   Draghici, Constantin ^b   Missir, Alexandru Vasile ^a  

^a CAROL DAVILA UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

^b ACADEMY OF ROMANIAN SCIENTISTS   (Romania)

Author keywords

1 Methyl 1H pyrazole 4 carboxylic acid; Acyl thiourea; Anticancer activity; Pyrazole amines; Thiazolylidenes

Indexed keywords

1 METHYL N (4 METHYL 3 PHENYLTHIAZOL 2(3H) YLIDENE) 1H PYRAZOLE 4 CARBOXAMIDE; 5 (1 METHYL 1H PYRAZOL 4 YL) 1 PHENYL 1,2 DIHYDRO 1,2,4 TRIAZOLE 3 THIONE; N (3 (4 CHLOROPHENYL) 4 METHYLTHIAZOL 2(3H) YLIDENE) 1 METHYL 1H PYRAZOLE 4 CARBOXAMIDE; N [(1 METHYL 1H PYRAZOLE 4 YL)CARBONYL] N' (2 METHOXYPHENYL) THIOUREA; N [(1 METHYL 1H PYRAZOLE 4 YL)CARBONYL] N' (2,4 DICHLOROPHENYL) THIOUREA; N [(1 METHYL 1H PYRAZOLE 4 YL)CARBONYL] N' (2,5 DICHLOROPHENYL) THIOUREA; N [(1 METHYL 1H PYRAZOLE 4 YL)CARBONYL] N' (2,6 DICHLOROPHENYL) THIOUREA; N [(1 METHYL 1H PYRAZOLE 4 YL)CARBONYL] N' (3 CHLOROPHNEYL) THIOUREA; N [(1 METHYL 1H PYRAZOLE 4 YL)CARBONYL] N' (3 METHOXYPHENYL) THIOUREA; N [(1 METHYL 1H PYRAZOLE 4 YL)CARBONYL] N' (4METHOXYPHENYL) THIOUREA; N BENZOYL N' (3 (4 BROMOPHENYL) 1H PYRAZOL 5 YL) THIOUREA; N BENZOYL N' (3 METHYL 1 PHENYL 1H PYRAZOL 5 YL) THIOUREA; N BENZOYL N' (5 METHYL 1H PYRAZOL 3 YL)THIOUREA; PYRAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; ASSAY; CANCER CELL CULTURE; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; PYRAZOLES;

EID: 77957827162     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2010.07.064     Document Type: Article

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