Cochlear efferent innervation and function

Current Opinion in Otolaryngology and Head and Neck Surgery

Volumn 18, Issue 5, 2010, Pages 447-453

  Guinan Jr , John J ^a,b,c  

^a MASSACHUSETTS EYE AND EAR INFIRMARY   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c HARVARD MIT DIVISION OF HEALTH SCIENCES AND TECHNOLOGY   (United States)

Author keywords

auditory development; auditory psychophysics; descending control; hearing; medial olivocochlear

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID RECEPTOR; ACETYLCHOLINE; CHOLINERGIC RECEPTOR; POTASSIUM CHANNEL;

ACOUSTIC NERVE FIBER; ATTENTION; AUDITORY CANAL; BINAURAL HEARING; COCHLEAR NERVE; COCHLEAR NUCLEUS; DISTORTION PRODUCT OTOACOUSTIC EMISSION; EFFERENT NERVE; GENE EXPRESSION; HAIR CELL; HEARING LOSS; HUMAN; LEARNING DISORDER; MEDIAL OLIVOCOCHLEAR; NERVE CELL PLASTICITY; NERVE FUNCTION; NONHUMAN; OLIVARY NUCLEUS; OTOACOUSTIC EMISSION; PIEZOELECTRICITY; PRIORITY JOURNAL; PSYCHOPHYSIOLOGY; RECEPTOR DOWN REGULATION; REVIEW; SOUND PRESSURE; SPEECH ANALYSIS; SPEECH PERCEPTION; TINNITUS; TONOTOPY;

COCHLEA; EFFERENT PATHWAYS; HAIR CELLS, AUDITORY; HUMANS; OLIVARY NUCLEUS;

EID: 77957812157     PISSN: 10689508     EISSN: None     Source Type: Journal    
DOI: 10.1097/MOO.0b013e32833e05d6     Document Type: Review

References (72)

1. Guinan JJ Jr. The physiology of olivocochlear efferents. In: Dallos PJ, Popper AN, Fay RR, editors. The cochlea. New York: Springer-Verlag; 1996. pp. 435-502.
2. Guinan JJ Jr. Olivocochlear efferents: anatomy, physiology, function, and the measurement of efferent effects in humans. Ear Hear 2006; 27:589-607.
3. Fex J. Efferent inhibition in the cochlea related to hair-cell dc activity: study of postsynaptic activity of the crossed olivo-cochlear fibers in the cat. J Acoust Soc Am 1967; 41:666-675.
4. Santos-Sacchi J. On the frequency limit and phase of outer hair cell motility: effects of the membrane filter. J Neurosci 1992; 12:1906-1916.
5. Rabbitt RD, Clifford S, Breneman KD, et al. Powerefficiency ofouter haircell somatic electromotility. PLoS Comput Biol 2009; 5:e1000444.
6. Cooper NP, Guinan JJ Jr. Efferent-mediated control of basilar membrane motion. J Physiol 2006; 576:49-54.
7. Guinan JJ Jr, Lin T, Cheng H. Medial-olivocochlear-efferent inhibition of the first peak of auditory-nerve responses: evidence for a new motion within the cochlea. J Acoust Soc Am 2005; 118:2421-2433.
8. Cooper N, Guinan JJ Jr. Efferent inhibition of the apical cochlea's mechanical responses to sound. Assoc Res Otolaryngol Abstr 2010; 34:41.
9. Winslow RL, Sachs MB. Effect of electrical stimulation of the crossed olivocochlear bundle on auditory nerve response to tones in noise. J Neurophysiol 1987; 57:1002-1021.
10. Lilaonitkul W, Guinan JJ Jr. Reflex control of the human innerear: a half-octave offset in medial efferent feedbackthat is consistent with an efferent role in the control of masking. J Neurophysiol 2009; 101:1394-1406.
11. Lilaonitkul W, Guinan JJ Jr. Medial olivocochlear (MOC) efferent acoustic reflexes in humans are widely tuned and have their biggest effects at frequencies above that of the eliciting sound. Assoc Res Otolaryngol Abstr 2008; 31:284. (#835).
12. Warren EH III, Liberman MC. Effects of contralateral sound on auditory-nerve responses. II: Dependence on stimulus variables. Hearing Res 1989; 37:105-122.
13. Walsh KP, Pasanen EG, Mc Fadden D. Properties of a nonlinearversion of the stimulus-frequencyotoacoustic emission. J Acoust Soc Am 2010; 127:955-969.
14. Lilaonitkul W, Guinan JJ Jr. Human medial olivocochlear reflex: effects as functions of contralateral, ipsilateral, and bilateral elicitor bandwidths. J Assoc Res Otolaryngol 2009; 10:459-470.
15. Francis NA, Guinan JJ Jr. Medial olivocochlear efferent stimulation by contralateral noise induces similar changes in stimulus-frequency and clickevoked otoacoustic measurements of cochlear filter-related delay. Hear Res 2010; 267:36-45.
16. Abdala C, Mishra SK, Williams TL Considering distortion productotoacoustic emission fine structure in measurements of the medial olivocochlear reflex. J Acoust Soc Am 2009; 125:1584-1594.
17. Deeter R, Abel R, Calandruccio L, Dhar S. Contralateral acoustic stimulation alters the magnitude and phase of distortion product otoacoustic emissions. J Acoust Soc Am 2009; 126:2413-2424.
18. Shera CA, Guinan JJ Jr. Evoked otoacoustic emissions arise by two funda-mentally different mechanisms: a taxonomy for mammalian OAEs. J Acoust Soc Am 1999; 105:782-798.
19. Wittekindt A, Gaese BH, Kossl M. Influence of contralateral acoustic stimulation on the quadratic distortion product f2-f1 in humans. Hear Res 2009; 247:27-33.
20. Abel C, Wittekindt A, Kossl M. Contralateral acoustic stimulation modulates low-frequency biasing of DPOAE: efferent influence on cochlear amplifier operating state?J Neurophysiol 2009; 101:2362-2371.
21. Van Zyl A, Swanepoel D, Hall JW 3rd. Effect of prolonged contralateral acoustic stimulation on transient evoked otoacoustic emissions. Hear Res 2009; 254:77-81.
22. Larsen E, Liberman MC. Slow build-up of cochlear suppression during sustained contralateral noise: central modulation of olivocochlear efferents? Hear Res 2009; 256:1-10.
23. Sridhar TS, Liberman MC, Brown MC, Sewell WF. A novel cholinergic 'slow effect' of olivocochlear stimulation on cochlear potentials in the guinea pig. J Neurosci 1995; 15:3667-3678.
24. Cooper NP, Guinan JJ Jr. Separate mechanical processes underlie fast and slow effects of medial olivocochlear efferent activity. J Physiol 2003; 548:307-312.
25. Maison SF, Vetter DE, Liberman MC. A novel effect of cochlear efferents: in vivo response enhancement does not require alpha9 cholinergic receptors. J Neurophysiol 2007; 97:3269-3278.
26. Guinan JJ, Backus BC, Lilaonitkul W, Aharonson V. Medial olivocochlear efferent reflex in humans: otoacoustic emission (OAE) measurement issues and the advantages of stimulus frequency OAEs. J Assoc Res Otolaryngol 2003; 4:521-540.
27. Backus BC, Guinan JJ Jr. Time course of the human medial olivocochlear reflex. J Acoust Soc Am 2006; 119:2889-2904.
28. Zhao W, Dhar S. The effect of contralateral acoustic stimulation on spontaneous otoacoustic emissions. J Assoc Res Otolaryngol 2010; 11:53-67.
29. Kawase T, Delgutte B, Liberman MC. Antimasking effects oftheolivocochlear reflex. II: Enhancement of auditory-nerve response to masked tones. J Neurophysiol 1993; 70:2533-2549. (Pubitemid 24006844)
30. Messing DP, Delhorne L, Bruckert E, et al. A nonlinearefferent-inspired model of the auditory system; matching human confusions in stationary noise. Speech Commun 2009; 51:668-683.
31. Brown GJ, Ferry RT, Meddis R. A computer model of auditory efferent suppression: implications for the recognition of speech in noise. J Acoust Soc Am 2010; 127:943-954.
32. Kumar UA, Vanaja CS. Functioning of olivocochlear bundle and speech perception in noise. Ear Hear 2004; 25:142-146.
33. Grataloup C, Hoen M, Veuillet E, et al. Speech restoration: an interactive process. J Speech Lang Hear Res 2009; 52:827-838.
34. Keefe DH, Schairer KS, Ellison JC, et al. Use of stimulus-frequency otoacoustic emissions to investigate efferent and cochlear contributions to temporal overshoot. J Acoust Soc Am 2009; 125:1595-1604
35. Walsh KP, Pasanen EG, Mc Fadden D. Overshoot measured physiologically and psychophysically in the same human ears. Hear Res (in press).
36. Jennings SG, Strickland EA, Heinz MG. Precursor effects on behavioral estimates of frequency selectivity and gain in forward masking. J Acoust Soc Am 2009; 125:2172-2181.
37. Wojtczak M, Oxenham AJ. On-and off-frequency forward masking by Schroeder-phase complexes. J Assoc Res Otolaryngol 2009; 10:595-607.
38. Zhou X, Henin S, Thompson SE, et al. Sensitization to masked tones following notched-noisecorrelateswith estimatesof cochlearfunction using distortion product otoacoustic emissions. J Acoust Soc Am 2010; 127: 970-976.
39. Harkrider AW, Bowers CD. Evidence for a cortically mediated release from inhibition in the human cochlea. J Am Acad Audiol 2009; 20:208-215.
40. De Boer J, Thornton AR. Neural correlates of perceptual learning in the auditory brainstem: efferent activity predicts and reflects improvement at a speech-in-noise discrimination task. J Neurosci 2008; 28:4929-4937.
41. Yalcinkaya F, Yilmaz ST, Muluk NB. Transient evoked otoacoustic emissions and contralateral suppressions in children with auditory listening problems. Auris Nasus Larynx 2010; 37:47-54.
42. Bajo VM, Nodal FR, Moore DR, King AJ. The descending corticocollicular pathway mediates learning-induced auditory plasticity. Nat Neurosci 2010; 13:253-260.
43. Reuss S, Disque-Kaiser U, Antoniou-Lipfert P, et al. Neurochemistry of olivocochlear neurons in the hamster. Anat Rec (Hoboken) 2009; 292: 461-471.
44. Lv P, Rodriguez-Contreras A, Jeong Kim H, et al. Release and elementary mechanisms of nitric oxide in hair cells. J Neurophysiol 2010; 103:2494-2505.
45. Keppler H, Dhooge I, Corthals P, et al. The effects of aging on evoked otoacoustic emissions and efferent suppression of transient evoked oto-acoustic emissions. Clin Neurophysiol 2010; 121:359-365.
46. Oliveira JR, Fernandes JC, Costa Filho OA. Age impact on the efferent system activities in cochlear mechanical properties in normal hearing individuals. Brazil J Otorhinolaryngol 2009; 75:340-344.
47. Paschoal CP, Azevedo MF. Cigarette smoking as a risk factor for auditory problems. Brazil J Otorhinolaryngol 2009; 75:893-902.
48. Vinay. Effect of smoking on transient evoked otoacoustic emissions and contralateral suppression. Auris Nasus Larynx 2010; 37:299-302.
49. Fernandes L, Santos TM. Tinnitusand normal hearing: astudyonthetransient otoacousticemissionssuppression. Brazil J Otorhinolaryngol 2009; 75:414-419.
50. Paglialonga A, Del Bo L, Ravazzani P, Tognola G. Quantitative analysis of cochlear active mechanisms in tinnitus patients with normal hearing sensi-tivity: multiparametric recording of evoked otoacoustic emissions and con-tralateral suppression. Auris Nasus Larynx 2010; 37:291-298.
51. Ugur AK, Kemaloglu YK, Ugur MB, et al. Otoacoustic emissionsand effects of contralateral white noise stimulation on transient evoked otoacoustic emissions in diabetic children. Int J Pediatric Otorhinolaryngol 2009; 73:555-559.
52. Darrow KN, Maison SF, Liberman MC. Cochlear efferent feedback balances interaural sensitivity. Nat Neurosci 2006; 9:1474-1476.
53. Larsen E, Liberman MC. Contralateral cochlear effects of ipsilateral damage: no evidence for interaural coupling. Hear Res 2010; 260:70-80.
54. Elgoyhen AB, Vetter DE, Katz E, et al. alpha10: a determinant of nicotinic cholinergic receptorfunction in mammalian vestibularand cochlear mechanosensory hair cells. Proc Natl Acad Sci USA 2001; 98:3501-3506.
55. Taranda J, Maison SF, Ballestero JA, et al. A point mutation in the hair cell nicotinic cholinergic receptor prolongs cochlear inhibition and enhances noise protection. PLoS Bio 2009; 7:e18.
56. Murthy V, Maison SF, Taranda J, et al. SK2 channels are required for function and long-term survival of efferent synapses on mammalian outer hair cells. Mol Cell Neurosci 2009; 40:39-49.
57. Murthy V, Taranda J, Elgoyhen AB, Vetter DE. Activity of nAChRs containing alpha9 subunits modulates synapse stabilization via bidirectional signaling programs. Dev Neurobiol 2009; 69:931-949.
58. Vetter DE, Liberman MC, Mann J, et al. Role of alpha 9 nicotinicACh receptor subunits in the development and function of cochlear efferent innervation. Neuron 1999; 23:93-103.
59. May BJ, Prosen CA, Weiss D, Vetter D. Behavioral investigation of some possible effects of the central olivocochlear pathways in transgenic mice. Hear Res 2002; 171:142-157.
60. Brown MC, Vetter DE. Olivocochlear neuron central anatomy is normal in alpha 9 knockout mice. J Assoc Res Otolaryngol 2009; 10:64-75.
61. May BJ, Budelis J, Niparko JK. Behavioral studiesof the olivocochlearefferent system: learning to listen in noise. Arch Otolaryngol Head Neck Surg 2004; 130:660-664.
62. Mulders WH, Paolini AG, Needham K, Robertson D. Synaptic responses in cochlear nucleus neurons evoked by activation of the olivocochlear system. Hear Res 2009; 256:85-92.
63. Bledsoe SC Jr, Koehler S, Tucci DL, et al. Ventral cochlear nucleus responses to contralateral sound are mediated by commissural and olivocochlear pathways. J Neurophysiol 2009; 102:886-900.
64. Elgoyhen AB, Franchini LF. Prestin and the cholinergic receptor of hair cells: positively-selected proteins in mammals. Hear Res (in press).
65. Elgoyhen AB, Katz E, Fuchs PA. The nicotinic receptorofcochlearhaircells: a possible pharmacotherapeutictarget? Biochem Pharmacol 2009; 78:712-719.
66. Mc Intosh JM, Absalom N, Chebib M, et al. Alpha9 nicotinic acetylcholine receptors and the treatment of pain. Biochem Pharmacol 2009; 78:693-702.
67. Turcan S, Slonim DK, Vetter DE. Lack of nAChR activity depresses cochlear maturation and up-regulates GABA system components: temporal profiling of gene expression in alpha9 null mice. PLoS One 2010; 5:e9058.
68. Maison SF, Casanova E, Holstein GR, et al. Loss of GABAB receptors in cochlear neurons: threshold elevation suggests modulation of outer hair cell function by type II afferent fibers. J Assoc Res Otolaryngol 2009; 10:50-63.
69. Simmons DD. Developmentof the innerearefferent systemacrossvertebrate species. J Neurobiol 2002; 53:228-250.
70. Taranda J, Ballestero JA, Hiel H, et al. Constitutive expression of the alpha10 nicotinic acetylcholine receptor subunit fails to maintain cholinergic re-sponses in innerhaircells afterthe onsetof hearing. J Assoc Res Otolaryngol 2009; 10:397-406.
71. Gomez-Casati ME, Wedemeyer C, Taranda J, et al. Electrical properties and functional expression of ionic channels in cochlear inner hair cells of mice lacking the alpha10 nicotinic cholinergic receptor subunit. J Assoc Res Otolaryngol 2009; 10:221-232.
72. Neef J, Gehrt A, Bulankina AV, et al. The Ca2+ channel subunit beta2 regulates Ca2+ channel abundance and function in inner hair cells and is required for hearing. J Neurosci 2009; 29:10730-10740.