-
1
-
-
77950627242
-
IL-1 pathways in inflammation and human diseases
-
Gabay C, Lamacchia C, Palmer G (2010) IL-1 pathways in inflammation and human diseases. Nat Rev Rheumatol 6:232-241
-
(2010)
Nat Rev Rheumatol
, vol.6
, pp. 232-241
-
-
Gabay, C.1
Lamacchia, C.2
Palmer, G.3
-
2
-
-
62649139025
-
Immunological and inflammatory functions of the interleukin-1 family
-
Dinarello CA (2009) Immunological and inflammatory functions of the interleukin-1 family. Annu Rev Immunol 27:519-550
-
(2009)
Annu Rev Immunol
, vol.27
, pp. 519-550
-
-
Dinarello, C.A.1
-
3
-
-
60749104683
-
The inflammasome: A caspase-1-activation platform that regulates immune responses and disease pathogenesis
-
Franchi L, Eigenbrod T, Munoz-Planillo R, Nunez G (2009) The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis. Nat Immunol 10:241-247
-
(2009)
Nat Immunol
, vol.10
, pp. 241-247
-
-
Franchi, L.1
Eigenbrod, T.2
Munoz-Planillo, R.3
Nunez, G.4
-
4
-
-
2342551979
-
Combination therapy with etanercept and anakinra in the treatment of patients with rheumatoid arthritis who have been treated unsuccessfully with methotrexate
-
Genovese MC, Cohen S, Moreland L et al (2004) Combination therapy with etanercept and anakinra in the treatment of patients with rheumatoid arthritis who have been treated unsuccessfully with methotrexate. Arthritis Rheum 50:1412-1419
-
(2004)
Arthritis Rheum
, vol.50
, pp. 1412-1419
-
-
Genovese, M.C.1
Cohen, S.2
Moreland, L.3
-
5
-
-
0037389680
-
Anakinra, a recombinant human interleukin-1 receptor antagonist (r-metHuIL-1ra), in patients with rheumatoid arthritis: A large, international, multicenter, placebo-controlled trial
-
Fleischmann RM, Schechtman J, Bennett R et al (2003) Anakinra, a recombinant human interleukin-1 receptor antagonist (r-metHuIL-1ra), in patients with rheumatoid arthritis: a large, international, multicenter, placebo-controlled trial. Arthritis Rheum 48:927-934
-
(2003)
Arthritis Rheum
, vol.48
, pp. 927-934
-
-
Fleischmann, R.M.1
Schechtman, J.2
Bennett, R.3
-
6
-
-
34248347919
-
What is the role for interleukin-1 receptor antagonist in rheumatic disease?
-
Lequerre T, Vittecoq O, Loet X le (2007) What is the role for interleukin-1 receptor antagonist in rheumatic disease? Joint Bone Spine 74:223-226
-
(2007)
Joint Bone Spine
, vol.74
, pp. 223-226
-
-
Lequerre, T.1
Vittecoq, O.2
Le Loet, X.3
-
7
-
-
67149130597
-
Anakinra for rheumatoid arthritis: A systematic review
-
Mertens M, Singh JA (2009) Anakinra for rheumatoid arthritis: a systematic review. J Rheumatol 36:1118-1125
-
(2009)
J Rheumatol
, vol.36
, pp. 1118-1125
-
-
Mertens, M.1
Singh, J.A.2
-
9
-
-
77954551165
-
Why not treat human cancer with interleukin-1 blockade?
-
Dinarello CA (2010) Why not treat human cancer with interleukin-1 blockade? Cancer Metastasis Rev 29:317-329
-
(2010)
Cancer Metastasis Rev
, vol.29
, pp. 317-329
-
-
Dinarello, C.A.1
-
10
-
-
77749304035
-
IL-1: Discoveries, controversies and future directions
-
Dinarello CA (2010) IL-1: discoveries, controversies and future directions. Eur J Immunol 40:599-606
-
(2010)
Eur J Immunol
, vol.40
, pp. 599-606
-
-
Dinarello, C.A.1
-
12
-
-
70450194415
-
Recommendations on therapy using interleukin-1beta-blocking agents
-
Manger B, Gaubitz M, Michels H (2009) Recommendations on therapy using interleukin-1beta-blocking agents. Z Rheumatol 68:766-771
-
(2009)
Z Rheumatol
, vol.68
, pp. 766-771
-
-
Manger, B.1
Gaubitz, M.2
Michels, H.3
-
13
-
-
70349411813
-
Aktualisiertes Therapieschema der Rheumatoiden Arthritis. Ergebnisse eines Konsensusprozesses deutscher Rheumatologen 2009
-
Wollenhaupt JAR, Backhaus M, Baerwald C et al (2009) Aktualisiertes Therapieschema der Rheumatoiden Arthritis. Ergebnisse eines Konsensusprozesses deutscher Rheumatologen 2009. Aktuelle Rheumatologie 34:234-239
-
(2009)
Aktuelle Rheumatologie
, vol.34
, pp. 234-239
-
-
Wollenhaupt, J.A.R.1
Backhaus, M.2
Baerwald, C.3
-
14
-
-
77953696525
-
EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs
-
Smolen JS, Landewe R, Breedveld FC et al (2010) EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs. Ann Rheum Dis 69:964-975
-
(2010)
Ann Rheum Dis
, vol.69
, pp. 964-975
-
-
Smolen, J.S.1
Landewe, R.2
Breedveld, F.C.3
-
16
-
-
46149100545
-
The human anti-IL-1 beta monoclonal antibody ACZ885 is effective in joint inflammation models in mice and in a proof-of-concept study in patients with rheumatoid arthritis
-
Alten R, Gram H, Joosten LA et al (2008) The human anti-IL-1 beta monoclonal antibody ACZ885 is effective in joint inflammation models in mice and in a proof-of-concept study in patients with rheumatoid arthritis. Arthritis Res Ther 10:R67
-
(2008)
Arthritis Res Ther
, vol.10
-
-
Alten, R.1
Gram, H.2
Joosten, L.A.3
-
17
-
-
70549106190
-
A multicentric, double-blind trial of anakinra versus placebo in systemic-onset juvenile idiopathic arthritis (ANAJIS trial): Efficacy and tolerance over 12 months
-
Quartier P, Allantaz, F, Cimaz, R et al (2008) A multicentric, double-blind trial of anakinra versus placebo in systemic-onset juvenile idiopathic arthritis (ANAJIS trial): efficacy and tolerance over 12 months. Arthritis Rheum 58:S632
-
(2008)
Arthritis Rheum
, vol.58
-
-
Quartier, P.1
Allantaz, F.2
Cimaz, R.3
-
18
-
-
39549109506
-
Interleukin-1 receptor antagonist (anakinra) treatment in patients with systemic-onset juvenile idiopathic arthritis or adult onset Still disease: Preliminary experience in France
-
Lequerre T, Quartier P, Rosellini D et al (2008) Interleukin-1 receptor antagonist (anakinra) treatment in patients with systemic-onset juvenile idiopathic arthritis or adult onset Still disease: preliminary experience in France. Ann Rheum Dis 67:302-308
-
(2008)
Ann Rheum Dis
, vol.67
, pp. 302-308
-
-
Lequerre, T.1
Quartier, P.2
Rosellini, D.3
-
19
-
-
34447635445
-
Preliminary evidence for bioactivity of IL-1 trap (Rilonacept), a long acting Il-1 inhibitor, in systemic juvenile idiopathic arthritis (sJIA)
-
Lovell DJ, Gianinni EH, Kimura Y et al (2006) Preliminary evidence for bioactivity of IL-1 trap (Rilonacept), a long acting Il-1 inhibitor, in systemic juvenile idiopathic arthritis (sJIA). Arthritis Rheum 54:S325
-
(2006)
Arthritis Rheum
, vol.54
-
-
Lovell, D.J.1
Gianinni, E.H.2
Kimura, Y.3
-
20
-
-
77957570802
-
Evaluation of safety and preliminary efficacy of canakinumab (ACZ885), a new IL-1-beta blocking monoclonal antibody, in children with systemic juvenile idiopathic arthritis (sJIA)
-
for PRINTO
-
Ruperto N, Quartier P, Wulfraat N et al (2009) for PRINTO. Evaluation of safety and preliminary efficacy of canakinumab (ACZ885), a new IL-1-beta blocking monoclonal antibody, in children with systemic juvenile idiopathic arthritis (sJIA). Arthritis Rheum 60:S2055
-
(2009)
Arthritis Rheum
, vol.60
-
-
Ruperto, N.1
Quartier, P.2
Wulfraat, N.3
-
21
-
-
49449094179
-
Efficacy and safety of rilonacept (interleukin-1 Trap) in patients with cryopyrin-associated periodic syndromes: Results from two sequential placebo-controlled studies
-
Hoffman HM, Throne ML, Amar NJ et al (2008) Efficacy and safety of rilonacept (interleukin-1 Trap) in patients with cryopyrin-associated periodic syndromes: results from two sequential placebo-controlled studies. Arthritis Rheum 58:2443-2452
-
(2008)
Arthritis Rheum
, vol.58
, pp. 2443-2452
-
-
Hoffman, H.M.1
Throne, M.L.2
Amar, N.J.3
-
22
-
-
66649102432
-
Use of canakinumab in the cryopyrin-associated periodic syndrome
-
Lachmann HJ, Kone-Paut I, Kuemmerle-Deschner JB et al (2009) Use of canakinumab in the cryopyrin-associated periodic syndrome. N Engl J Med 360:2416-2425
-
(2009)
N Engl J Med
, vol.360
, pp. 2416-2425
-
-
Lachmann, H.J.1
Kone-Paut, I.2
Kuemmerle-Deschner, J.B.3
-
23
-
-
43949128071
-
Persistent efficacy of anakinra in patients with tumor necrosis factor receptor-associated periodic syndrome
-
Gattorno M, Pelagatti MA, Meini A et al (2008) Persistent efficacy of anakinra in patients with tumor necrosis factor receptor-associated periodic syndrome. Arthritis Rheum 58:1516-1520
-
(2008)
Arthritis Rheum
, vol.58
, pp. 1516-1520
-
-
Gattorno, M.1
Pelagatti, M.A.2
Meini, A.3
-
24
-
-
77950629486
-
Clinical effects of prainacasan (PRAL), an orally-active interleukin-1β converting enzyme (ICE) inhibitor, in a 285 patient phase II trial in rheumatoid arthritis (abstract LB02)
-
Pavelka K (2002) Clinical effects of prainacasan (PRAL), an orally-active interleukin-1β converting enzyme (ICE) inhibitor, in a 285 patient phase II trial in rheumatoid arthritis (abstract LB02). Arthritis Rheum 46:3415
-
(2002)
Arthritis Rheum
, vol.46
, pp. 3415
-
-
Pavelka, K.1
-
25
-
-
84867894249
-
Efficacy of anakinra treatment in a patient with colchicine-resistant familial Mediterranean fever
-
[Epub ahead of print]
-
Alpay N, Sumnu A, Caliskan Y et al (2010) Efficacy of anakinra treatment in a patient with colchicine-resistant familial Mediterranean fever. Rheumatol Int [Epub ahead of print]
-
(2010)
Rheumatol Int
-
-
Alpay, N.1
Sumnu, A.2
Caliskan, Y.3
-
26
-
-
75749100258
-
IL1-receptor antagonist anakinra provides long-lasting efficacy in the treatment of refractory adult-onset Still's disease
-
Naumann L, Feist E, Natusch A et al (2010) IL1-receptor antagonist anakinra provides long-lasting efficacy in the treatment of refractory adult-onset Still's disease. Ann Rheum Dis 69:466-467
-
(2010)
Ann Rheum Dis
, vol.69
, pp. 466-467
-
-
Naumann, L.1
Feist, E.2
Natusch, A.3
-
27
-
-
34547878809
-
Anakinra in patients with treatment-resistant adult-onset Still's disease: Four case reports with serial cytokine measurements and a review of the literature
-
Kotter I, Wacker A, Koch S et al (2007) Anakinra in patients with treatment-resistant adult-onset Still's disease: four case reports with serial cytokine measurements and a review of the literature. Semin Arthritis Rheum 37:189-197
-
(2007)
Semin Arthritis Rheum
, vol.37
, pp. 189-197
-
-
Kotter, I.1
Wacker, A.2
Koch, S.3
-
28
-
-
35348923754
-
The role of interleukin-1 and the inflammasome in gout: Implications for therapy
-
Pope RM, Tschopp J (2007) The role of interleukin-1 and the inflammasome in gout: implications for therapy. Arthritis Rheum 56:3183-3188
-
(2007)
Arthritis Rheum
, vol.56
, pp. 3183-3188
-
-
Pope, R.M.1
Tschopp, J.2
-
29
-
-
67449124615
-
Erosive osteoarthritis of the hand: Clinical experience with anakinra
-
Bacconnier L, Jorgensen C, Fabre S (2009) Erosive osteoarthritis of the hand: clinical experience with anakinra. Ann Rheum Dis 68:1078-1079
-
(2009)
Ann Rheum Dis
, vol.68
, pp. 1078-1079
-
-
Bacconnier, L.1
Jorgensen, C.2
Fabre, S.3
-
30
-
-
34247170807
-
Interleukin-1-receptor antagonist in type 2 diabetes mellitus
-
Larsen CM, Faulenbach M, Vaag A et al (2007) Interleukin-1-receptor antagonist in type 2 diabetes mellitus. N Engl J Med 356:1517-1526
-
(2007)
N Engl J Med
, vol.356
, pp. 1517-1526
-
-
Larsen, C.M.1
Faulenbach, M.2
Vaag, A.3
-
31
-
-
77954222687
-
Dysregulation of P2X7 receptor-inflammasome axis in SAPHO syndrome: Successful treatment with anakinra
-
Colina M, Pizzirani C, Khodeir M et al (2010) Dysregulation of P2X7 receptor-inflammasome axis in SAPHO syndrome: successful treatment with anakinra. Rheumatology (Oxford) 49:1416-1418
-
(2010)
Rheumatology (Oxford)
, vol.49
, pp. 1416-1418
-
-
Colina, M.1
Pizzirani, C.2
Khodeir, M.3
|