메뉴 건너뛰기




Volumn 132, Issue 1, 2010, Pages 48-55

Acute and sub-chronic toxicity of a lyophilised aqueous extract of Centaurium erythraea in rodents

Author keywords

Acute and sub chronic toxicity; Biochemical parameters; Centaurium erythraea Rafn.; Centaury; Hematological parameters; Lyophilised aqueous extract; Mice; Plant medicine; Rats; Rodents

Indexed keywords

CENTAURIUM ERYTHRAEA EXTRACT; GLUCOSE; PLANT EXTRACT; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

EID: 77957770748     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2010.07.038     Document Type: Article
Times cited : (43)

References (72)
  • 1
    • 0002363371 scopus 로고
    • Etude de l' effet hypoglycémiant sur des rats d'une association de Ammi visnaga, Centaurium erythraea et Thymus ciliatus utilisées en médecine traditionnelle Marocaine
    • Alaoui T., Benabdelkrim I., Zaid A. Etude de l' effet hypoglycémiant sur des rats d'une association de Ammi visnaga, Centaurium erythraea et Thymus ciliatus utilisées en médecine traditionnelle Marocaine. Al Biruniya Revue Marocaine de Pharmacognosie 1992, 8:37-44.
    • (1992) Al Biruniya Revue Marocaine de Pharmacognosie , vol.8 , pp. 37-44
    • Alaoui, T.1    Benabdelkrim, I.2    Zaid, A.3
  • 2
    • 0036977297 scopus 로고    scopus 로고
    • Characterization of the LOAEL-to-NOAEL uncertainty factor for mild adverse effects from acute inhalation exposures
    • Alexeeff G.V., Broadwin R., Liaw J., Dawson S.V. Characterization of the LOAEL-to-NOAEL uncertainty factor for mild adverse effects from acute inhalation exposures. Regulatory Toxicology and Pharmacology 2002, 36:96-105.
    • (2002) Regulatory Toxicology and Pharmacology , vol.36 , pp. 96-105
    • Alexeeff, G.V.1    Broadwin, R.2    Liaw, J.3    Dawson, S.V.4
  • 3
    • 0028037942 scopus 로고
    • Hypoglycaemic effect of Artemisia herba alba. II. Effect of a valuable extract on some blood parameters in diabetic animals
    • Al-Shamouny L., Al-Khazraji S.M., Twaij H.A.A. Hypoglycaemic effect of Artemisia herba alba. II. Effect of a valuable extract on some blood parameters in diabetic animals. Journal of Ethnopharmacology 1994, 43:167-171.
    • (1994) Journal of Ethnopharmacology , vol.43 , pp. 167-171
    • Al-Shamouny, L.1    Al-Khazraji, S.M.2    Twaij, H.A.A.3
  • 5
    • 67349139213 scopus 로고    scopus 로고
    • Plantes médicinales au Maghreb et soins de base (Précis de phytothérapie moderne)
    • Bellakhdar, J., 2006. Plantes médicinales au Maghreb et soins de base (Précis de phytothérapie moderne). Editions Le Fennec, Casablanca (Maroc), 386 p.
    • (2006) Editions Le Fennec, Casablanca (Maroc) , pp. 386
    • Bellakhdar, J.1
  • 7
    • 0025971229 scopus 로고
    • Antiinflammatory, analgesic, and antipyretic effects of an aqueous extract of Erythraea centaurium
    • Berkan T., Üstünes L., Lermioglu F., Özer A. Antiinflammatory, analgesic, and antipyretic effects of an aqueous extract of Erythraea centaurium. Planta Medica 1991, 57:34-37.
    • (1991) Planta Medica , vol.57 , pp. 34-37
    • Berkan, T.1    Üstünes, L.2    Lermioglu, F.3    Özer, A.4
  • 13
    • 0024954311 scopus 로고
    • Drogues de pharmacopée traditionnelle de la région de Rabat-Salé. II. Dicotylédones
    • Claisse R. Drogues de pharmacopée traditionnelle de la région de Rabat-Salé. II. Dicotylédones. Plantes Médicinales et phytothérapie 1989, 23:315-331.
    • (1989) Plantes Médicinales et phytothérapie , vol.23 , pp. 315-331
    • Claisse, R.1
  • 15
    • 0008552674 scopus 로고    scopus 로고
    • Measurement of triglyceride concentration
    • AACC Press, Washington, N. Riafi, G.R. Warnick, M.H. Dominiczak (Eds.)
    • Cole T.G., Klotzsch S.G., McNamara J. Measurement of triglyceride concentration. Handbook of Lipoprotein Testing 1997, 115-126. AACC Press, Washington. N. Riafi, G.R. Warnick, M.H. Dominiczak (Eds.).
    • (1997) Handbook of Lipoprotein Testing , pp. 115-126
    • Cole, T.G.1    Klotzsch, S.G.2    McNamara, J.3
  • 17
    • 0020589017 scopus 로고
    • Kinetic enzymatic method for automated determination of total cholesterol in serum
    • Deeg R., Ziegenhorn J. Kinetic enzymatic method for automated determination of total cholesterol in serum. Clinical Chemistry 1983, 29:1798-1802.
    • (1983) Clinical Chemistry , vol.29 , pp. 1798-1802
    • Deeg, R.1    Ziegenhorn, J.2
  • 18
    • 7044263520 scopus 로고    scopus 로고
    • Toxins: their toxicity and distribution in plant genera
    • CRC Press, New York
    • Duke J.A. Toxins: their toxicity and distribution in plant genera. Handbook of Medicinal Herbs 2000, CRC Press, New York, pp 696.
    • (2000) Handbook of Medicinal Herbs , pp. 696
    • Duke, J.A.1
  • 20
    • 0015109591 scopus 로고
    • Automated reaction-rate method for determination of serum creatinine CentrifiChem
    • Fabiny D.L., Ertingshausen G. Automated reaction-rate method for determination of serum creatinine CentrifiChem. Clinical Chemistry 1971, 17:696-700.
    • (1971) Clinical Chemistry , vol.17 , pp. 696-700
    • Fabiny, D.L.1    Ertingshausen, G.2
  • 21
    • 0004909855 scopus 로고
    • Petit Guide Panoramique des Herbes Médicinales
    • Delachaux et Niestlé Publishers, Lausanne, Switzerland
    • Flück H. Petit Guide Panoramique des Herbes Médicinales. Delachaux et Niestlé Publishers, Lausanne, Switzerland, 1973, p. 119.
    • (1973) , pp. 119
    • Flück, H.1
  • 22
    • 77957797566 scopus 로고
    • Les quatre flores de France, Editions Lechevalier, Paris
    • Fournier, P., 1961. Les quatre flores de France, Editions Lechevalier, Paris.
    • (1961)
    • Fournier, P.1
  • 24
    • 77957771218 scopus 로고
    • Dover Publications, New York
    • Grieve M. A Modern Herbal 1971, vol. 1. Dover Publications, New York, pp. 443.
    • (1971) A Modern Herbal , vol.1 , pp. 443
    • Grieve, M.1
  • 25
    • 0033879539 scopus 로고    scopus 로고
    • Experimental diuretic effects of Rosmarinus officinalis and Centaurium erythraea
    • Haloui M., Louedec L., Michel J.P., Lyoussi L. Experimental diuretic effects of Rosmarinus officinalis and Centaurium erythraea. Journal of Ethnopharmacology 2000, 71:465-472.
    • (2000) Journal of Ethnopharmacology , vol.71 , pp. 465-472
    • Haloui, M.1    Louedec, L.2    Michel, J.P.3    Lyoussi, L.4
  • 26
    • 77649179291 scopus 로고    scopus 로고
    • Prevention of type 2 diabetes induced by high fat diet in the C57BL/6J mouse by two medicinal plants used in traditional treatment of diabetes in the east of Algeria
    • Hamza N., Berke B., Cheze C., Agli A.-N., Robinson P., Gin H., Moore N. Prevention of type 2 diabetes induced by high fat diet in the C57BL/6J mouse by two medicinal plants used in traditional treatment of diabetes in the east of Algeria. Journal of Ethnopharmacology 2010, 128:513-518.
    • (2010) Journal of Ethnopharmacology , vol.128 , pp. 513-518
    • Hamza, N.1    Berke, B.2    Cheze, C.3    Agli, A.-N.4    Robinson, P.5    Gin, H.6    Moore, N.7
  • 27
    • 0017472360 scopus 로고
    • Etude de Centaurium umbellatum Gil. Identification des acides phénols
    • Hatjimanoli M., Debelmas A.M. Etude de Centaurium umbellatum Gil. Identification des acides phénols. Annales Pharmaceutiques Françaises 1977, 35:107-111.
    • (1977) Annales Pharmaceutiques Françaises , vol.35 , pp. 107-111
    • Hatjimanoli, M.1    Debelmas, A.M.2
  • 28
    • 77957781047 scopus 로고
    • Monohydroxy- and 2,5-dihydroxy terephthalic acids, two unusual phenolics isolated from Centaurium erythraea and identified in other Gentianaceae members
    • Hatjimanoli M., Favre-Bonvin J., Kaouadji M., Mariotte A.-M. Monohydroxy- and 2,5-dihydroxy terephthalic acids, two unusual phenolics isolated from Centaurium erythraea and identified in other Gentianaceae members. Annales Pharmaceutiques Française 1988, 35:107-111.
    • (1988) Annales Pharmaceutiques Française , vol.35 , pp. 107-111
    • Hatjimanoli, M.1    Favre-Bonvin, J.2    Kaouadji, M.3    Mariotte, A.-M.4
  • 29
    • 0000963308 scopus 로고
    • 50) calculation
    • 50) calculation. Biometrics 1956, 12:312-322.
    • (1956) Biometrics , vol.12 , pp. 312-322
    • Horn, H.J.1
  • 30
    • 77957778064 scopus 로고
    • Committee on Standards, IFCC. Revised IFCC method for aspartate aminotransferase (l-aspartate: 2-oxoglutarate aminotrasferase, EC 2.6.1.1)
    • IFCC (International Federation of Clinical Chemistry)
    • IFCC (International Federation of Clinical Chemistry) Committee on Standards, IFCC. Revised IFCC method for aspartate aminotransferase (l-aspartate: 2-oxoglutarate aminotrasferase, EC 2.6.1.1). Clinical Chemistry and Laboratory Medicine 1977, 15:719-720.
    • (1977) Clinical Chemistry and Laboratory Medicine , vol.15 , pp. 719-720
  • 31
    • 0018837729 scopus 로고
    • IFCC methods for the measurement of catalytic concentration of enzymes, Part 3. IFCC Method for alanine aminotransferase (l-alanine: 2-oxoglutarate aminotrasferase, EC 2.6.1.2)
    • IFCC (International Federation of Clinical Chemistry)
    • IFCC (International Federation of Clinical Chemistry) IFCC methods for the measurement of catalytic concentration of enzymes, Part 3. IFCC Method for alanine aminotransferase (l-alanine: 2-oxoglutarate aminotrasferase, EC 2.6.1.2). Clinica Chimica Acta 1980, 105:147-154F.
    • (1980) Clinica Chimica Acta , vol.105
  • 32
    • 0000841697 scopus 로고    scopus 로고
    • Uber den Niederschlag, welchen Pikrinsäure in normalen Harn erzeugt und über neue Reaktion des Kreatinines
    • Jaffe M. Uber den Niederschlag, welchen Pikrinsäure in normalen Harn erzeugt und über neue Reaktion des Kreatinines. Hoppe-Seylers Zeitschrift fur Physiologische Chemie 2003, 10:391-400.
    • (2003) Hoppe-Seylers Zeitschrift fur Physiologische Chemie , vol.10 , pp. 391-400
    • Jaffe, M.1
  • 33
    • 0034891429 scopus 로고    scopus 로고
    • Ethnobotanical survey of medicinal plants used for the treatment of diabetes, cardiac and renal diseases in the North centre region of Morocco (Fez-Boulemane)
    • Jouad H., Haloui M., Rhiouani H., El Hilaly J., Eddouks M. Ethnobotanical survey of medicinal plants used for the treatment of diabetes, cardiac and renal diseases in the North centre region of Morocco (Fez-Boulemane). Journal of Ethnopharmacology 2001, 77:175-182.
    • (2001) Journal of Ethnopharmacology , vol.77 , pp. 175-182
    • Jouad, H.1    Haloui, M.2    Rhiouani, H.3    El Hilaly, J.4    Eddouks, M.5
  • 35
    • 37049013905 scopus 로고    scopus 로고
    • Insecticidal effects of extracts of seven plant species on larval development, α-amylase activity and offspring production of Tribolium castaneum (Herbst) (Insecta: Coleoptera: Tenebrionidae)
    • Jbilou R., Amri H., Bouayad N., Ghailani N., Ennabili A., Sayah F. Insecticidal effects of extracts of seven plant species on larval development, α-amylase activity and offspring production of Tribolium castaneum (Herbst) (Insecta: Coleoptera: Tenebrionidae). Bioresource Technology 2008, 99:959-964.
    • (2008) Bioresource Technology , vol.99 , pp. 959-964
    • Jbilou, R.1    Amri, H.2    Bouayad, N.3    Ghailani, N.4    Ennabili, A.5    Sayah, F.6
  • 38
    • 34047221105 scopus 로고    scopus 로고
    • Medicinal plants used in Ki{dotless}rklareli Province (Turkey)
    • Kültür S. Medicinal plants used in Ki{dotless}rklareli Province (Turkey). Journal of Ethnopharmacology 2007, 111:341-364.
    • (2007) Journal of Ethnopharmacology , vol.111 , pp. 341-364
    • Kültür, S.1
  • 42
    • 0037291949 scopus 로고    scopus 로고
    • Bioactivity of gentiopicroside from the aerial parts of Centaurium erythraea
    • Kumarasamy Y., Nahar L., Sarker S.D. Bioactivity of gentiopicroside from the aerial parts of Centaurium erythraea. Fitoterapia 2003, 74:151-154.
    • (2003) Fitoterapia , vol.74 , pp. 151-154
    • Kumarasamy, Y.1    Nahar, L.2    Sarker, S.D.3
  • 43
    • 0015666819 scopus 로고
    • Connaissance du droguier algérien. A propos de deux plantes à propriétés fébrifuges: Ptychotis ammoïdes et Erythraea centaurium
    • Lacroix R., Merad R., Lacroix J., Abtroun N., Schoebel M.F. Connaissance du droguier algérien. A propos de deux plantes à propriétés fébrifuges: Ptychotis ammoïdes et Erythraea centaurium. Tunisie Médicale 1973, 51:327-331.
    • (1973) Tunisie Médicale , vol.51 , pp. 327-331
    • Lacroix, R.1    Merad, R.2    Lacroix, J.3    Abtroun, N.4    Schoebel, M.F.5
  • 46
    • 40149108043 scopus 로고    scopus 로고
    • The hypolipidemic effects of Artemisia sieberi (A. herba-alba) in alloxan induced diabetic rats
    • Mansi K., Amneh M., Nasr H. The hypolipidemic effects of Artemisia sieberi (A. herba-alba) in alloxan induced diabetic rats. International Journal of Pharmacology 2007, 3:487-491.
    • (2007) International Journal of Pharmacology , vol.3 , pp. 487-491
    • Mansi, K.1    Amneh, M.2    Nasr, H.3
  • 47
    • 2942534180 scopus 로고    scopus 로고
    • Hepatoprotective activity of Centaurium erythraea on acetaminophen-induced hepatotoxicity in rats
    • Mroueh M., Saab Y., Rizkallah R. Hepatoprotective activity of Centaurium erythraea on acetaminophen-induced hepatotoxicity in rats. Phytotherapy Research 2004, 18:431-433.
    • (2004) Phytotherapy Research , vol.18 , pp. 431-433
    • Mroueh, M.1    Saab, Y.2    Rizkallah, R.3
  • 50
    • 0016374492 scopus 로고
    • Detection and measurement of total bilirubin in serum, with use of surfactants as solubilizing agents
    • Pearlman F.C., Lee R.T.Y. Detection and measurement of total bilirubin in serum, with use of surfactants as solubilizing agents. Clinical Chemistry 1974, 20:447-453.
    • (1974) Clinical Chemistry , vol.20 , pp. 447-453
    • Pearlman, F.C.1    Lee, R.T.Y.2
  • 51
    • 0037199140 scopus 로고    scopus 로고
    • Effect of prolonged vigabatrin treatment on hematological and biochemical parameters in plasma, liver and kidney of Swiss albino mice
    • Raza M., Al-Shabanah O.A., El-Hadiyah T.M., Al-Majed A.A. Effect of prolonged vigabatrin treatment on hematological and biochemical parameters in plasma, liver and kidney of Swiss albino mice. Scientia Pharmaceutica 2002, 70:135-145.
    • (2002) Scientia Pharmaceutica , vol.70 , pp. 135-145
    • Raza, M.1    Al-Shabanah, O.A.2    El-Hadiyah, T.M.3    Al-Majed, A.A.4
  • 52
    • 0030470739 scopus 로고    scopus 로고
    • Polymethoxylated xanthones from the herb of Centaurium erythraea with strong antimutagenic properties in Salmonella typhimurium
    • Schimmer O., Mauthner H. Polymethoxylated xanthones from the herb of Centaurium erythraea with strong antimutagenic properties in Salmonella typhimurium. Planta Medica 1996, 62:561-564.
    • (1996) Planta Medica , vol.62 , pp. 561-564
    • Schimmer, O.1    Mauthner, H.2
  • 54
    • 33644821275 scopus 로고    scopus 로고
    • Effects of a single administration of acarbose on postprandial glucose excursion and endothelial dysfunction in type 2 diabetic patients: a randomized crossover study
    • Shimabukuro M., Higa N., Chinen I., Yamakawa K., Takasu N. Effects of a single administration of acarbose on postprandial glucose excursion and endothelial dysfunction in type 2 diabetic patients: a randomized crossover study. Journal of Clinical Endocrinology and Metabolism 2006, 91:837-842.
    • (2006) Journal of Clinical Endocrinology and Metabolism , vol.91 , pp. 837-842
    • Shimabukuro, M.1    Higa, N.2    Chinen, I.3    Yamakawa, K.4    Takasu, N.5
  • 56
    • 3042573028 scopus 로고    scopus 로고
    • Centaurium erythraea - the medicinal plant of the year 2004
    • Springefeld K. Centaurium erythraea - the medicinal plant of the year 2004. Pharmazeutische Zeitung 2004, 149:30.
    • (2004) Pharmazeutische Zeitung , vol.149 , pp. 30
    • Springefeld, K.1
  • 57
    • 0019989112 scopus 로고
    • Studies on the constituents of Erythraea centaurium (Linné) Persoon. II. The structure of centauroside, a new bis-secoiridoid glucoside
    • Takagi S., Yamaki M., Yumioka E., Nishimura T., Sakina K. Studies on the constituents of Erythraea centaurium (Linné) Persoon. II. The structure of centauroside, a new bis-secoiridoid glucoside. Yakugaku Zasshi 1982, 102:313-317.
    • (1982) Yakugaku Zasshi , vol.102 , pp. 313-317
    • Takagi, S.1    Yamaki, M.2    Yumioka, E.3    Nishimura, T.4    Sakina, K.5
  • 58
    • 0018403650 scopus 로고
    • Simplified enzymic/colorimetric serum urea nitrogen determination
    • Tabacco A., Meiattini F., Moda E., Tarli P. Simplified enzymic/colorimetric serum urea nitrogen determination. Clinical Chemistry 1979, 25:336-337.
    • (1979) Clinical Chemistry , vol.25 , pp. 336-337
    • Tabacco, A.1    Meiattini, F.2    Moda, E.3    Tarli, P.4
  • 59
    • 0037107609 scopus 로고    scopus 로고
    • A 90-day oral gavage toxicity study of d-methylphenidate and d,l-methylphenidate in Sprague-Dawley rats
    • Teo S., Stirling D., Thomas S., Hoberman A., Kiorpes A., Khetani V. A 90-day oral gavage toxicity study of d-methylphenidate and d,l-methylphenidate in Sprague-Dawley rats. Toxicology 2002, 179:183-196.
    • (2002) Toxicology , vol.179 , pp. 183-196
    • Teo, S.1    Stirling, D.2    Thomas, S.3    Hoberman, A.4    Kiorpes, A.5    Khetani, V.6
  • 60
    • 0032990192 scopus 로고    scopus 로고
    • Effects of long-term caffeine consumption on renal function in spontaneously hypertensive heart failure prone rats
    • Tofovic S.P., Jackson E.K. Effects of long-term caffeine consumption on renal function in spontaneously hypertensive heart failure prone rats. Journal of Cardiovascular Pharmacology 1999, 33:360-366.
    • (1999) Journal of Cardiovascular Pharmacology , vol.33 , pp. 360-366
    • Tofovic, S.P.1    Jackson, E.K.2
  • 61
    • 0021041515 scopus 로고
    • Some pharmacological, toxicological and phytochemical investigation on Centaurea phyllocephala
    • Twaij H.A.A., Kery A., Al Khazraji N.K. Some pharmacological, toxicological and phytochemical investigation on Centaurea phyllocephala. Journal of Ethnopharmacology 1983, 9:299-314.
    • (1983) Journal of Ethnopharmacology , vol.9 , pp. 299-314
    • Twaij, H.A.A.1    Kery, A.2    Al Khazraji, N.K.3
  • 62
    • 0141495518 scopus 로고    scopus 로고
    • Isolation and structural elucidation of 5-formyl-2,3-dihydroisocoumarin from Centaurium erythraea aerial parts
    • Valentão P, Andrade P.B., Silva A.M.S., Moreira M.M., Seabra R.M. Isolation and structural elucidation of 5-formyl-2,3-dihydroisocoumarin from Centaurium erythraea aerial parts. Natural Product Research 2003, 15:361-364.
    • (2003) Natural Product Research , vol.15 , pp. 361-364
    • Valentão, P.1    Andrade, P.B.2    Silva, A.M.S.3    Moreira, M.M.4    Seabra, R.M.5
  • 65
    • 0034839984 scopus 로고    scopus 로고
    • Antioxidant activity of Centaurium erythraea infusion evidenced by its superoxide radical scavenging and xanthine oxidase inhibitory activity
    • Valentão P., Fernandas E., Carvalho F., Andrade P.B., Seabra R.M., Bastos M.L. Antioxidant activity of Centaurium erythraea infusion evidenced by its superoxide radical scavenging and xanthine oxidase inhibitory activity. Journal of Agricultural and Food Chemistry 2001, 49:3476-3479.
    • (2001) Journal of Agricultural and Food Chemistry , vol.49 , pp. 3476-3479
    • Valentão, P.1    Fernandas, E.2    Carvalho, F.3    Andrade, P.B.4    Seabra, R.M.5    Bastos, M.L.6
  • 66
    • 0042338758 scopus 로고    scopus 로고
    • Hydroxyl radical and hypochlorous acid scavenging activity of small centaury (Centaurium erythraea) infusion. A comparative study with green tea (Camellia sinensis)
    • Valentão P., Fernandes E., Carvalho F., Andrade P.B., Seabra R.M., Bastos M.L. Hydroxyl radical and hypochlorous acid scavenging activity of small centaury (Centaurium erythraea) infusion. A comparative study with green tea (Camellia sinensis). Phytomedicine 2003, 10:517-522.
    • (2003) Phytomedicine , vol.10 , pp. 517-522
    • Valentão, P.1    Fernandes, E.2    Carvalho, F.3    Andrade, P.B.4    Seabra, R.M.5    Bastos, M.L.6
  • 67
    • 0019454940 scopus 로고
    • Secoiridoids and xanthones in the genus Centaurium. Part III: decentapicrins A, B and C, new m-hydroxybenzoyl esters of sweroside from Centaurium Littorale
    • Van Der Sluis W.G., Labadie R.P. Secoiridoids and xanthones in the genus Centaurium. Part III: decentapicrins A, B and C, new m-hydroxybenzoyl esters of sweroside from Centaurium Littorale. Planta Medica 1981, 41:150-160.
    • (1981) Planta Medica , vol.41 , pp. 150-160
    • Van Der Sluis, W.G.1    Labadie, R.P.2
  • 68
    • 0024813501 scopus 로고
    • Extrapolation of pharmacological and toxicological data based on metabolic weight
    • VanMiert A.S.J.P.A.M. Extrapolation of pharmacological and toxicological data based on metabolic weight. Archiv fur Experimentelle Veterinarmedizin 1989, 43:481-488.
    • (1989) Archiv fur Experimentelle Veterinarmedizin , vol.43 , pp. 481-488
    • VanMiert, A.S.J.P.A.M.1
  • 71
    • 0343496546 scopus 로고
    • Experimental and clinical aspect of drug toxicity
    • Zbinden G. Experimental and clinical aspect of drug toxicity. Advances in Pharmacology 1963, 2:1-112.
    • (1963) Advances in Pharmacology , vol.2 , pp. 1-112
    • Zbinden, G.1
  • 72
    • 0019391510 scopus 로고
    • 50 test for the toxicological evaluation of chemical substances
    • 50 test for the toxicological evaluation of chemical substances. Archives of Toxicology 1981, 47:77-99.
    • (1981) Archives of Toxicology , vol.47 , pp. 77-99
    • Zbinden, G.1    Flury-Roversi, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.