Hepatoprotective activity of Centaurium erythraea on acetaminophen-induced hepatotoxicity in rats

Phytotherapy Research

Volumn 18, Issue 5, 2004, Pages 431-433

  Mroueh, Mohamad ^a   Saab, Yolande ^a   Rizkallah, Raed ^a  

^a LEBANESE AMERICAN UNIVERSITY   (Lebanon)

Author keywords

Acetaminophen; Centaurium erythraea; Hepatoprotective; Hepatotoxicity; Rats

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CENTAURIUM ERYTHRAEA EXTRACT; LACTATE DEHYDROGENASE; LIVER PROTECTIVE AGENT; PARACETAMOL; UNCLASSIFIED DRUG;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CONTROLLED STUDY; DOSE RESPONSE; DRUG ACTIVITY; DRUG EFFECT; DRUG ISOLATION; DRUG RESEARCH; DRUG SCREENING; HISTOPATHOLOGY; LACTATE DEHYDROGENASE BLOOD LEVEL; LIVER PROTECTION; LIVER TOXICITY; MALE; NONHUMAN; PLANT LEAF; RAT; TISSUE SECTION;

ACETAMINOPHEN; ANIMALS; CENTAURIUM; HEPATITIS, TOXIC; LIVER; MALE; PHYTOTHERAPY; PLANT COMPONENTS, AERIAL; PLANT EXTRACTS; PROTECTIVE AGENTS; RATS; RATS, WISTAR;

CENTAURIUM; CENTAURIUM ERYTHRAEA; GENTIANACEAE;

EID: 2942534180     PISSN: 0951418X     EISSN: None     Source Type: Journal    
DOI: 10.1002/ptr.1498     Document Type: Article

References (7)

1. Berkan T, Ustunes L, Lermioglu F, Ozer A. 1991. Antiinflammatory, analgesic, and antipyretic effects of aqueous extract of Erythraea Centaurium. Planta Medica. 57(1), 34-37.
2. Bisset NG. 1994. Herbal Drugs and Phytopharmaceuticals. Medpharm GmbH Scientific Publishers: Stuttgart, Germany.
3. Haloui M, Louedec L, Michel JB, Lyoussi B. 2000. Experimental diuretic effects of Rosamarinus officinalis and Centaurium erythraea. Journal of Ethnopharmacology. 71(3), 465-472.
4. Mitchell JR. 1988. Acetaminophen toxicity. N. Engl. J. Med. 319, 1601-1602.
5. Schimmer O, Mauthner H. 1994. Centarium erythraea. Zeitschrift-fur- Phytotherapie. 15(5), 299-306.
6. Savides MC, Oehme FW. 1983. Acetaminophen and its toxicity. J. Appl. Toxicol. 3, 95-111.
7. Vermeulen NPF, Bessems JGM, Van'de Streat R. 1992. Molecular aspects of paracetamol iduced hepatotoxicity and its mechanism based prevention. Drug Metabol. Rev. 24, 367-407.