Synaesthetic colour in the brain: Beyond colour areas. A functional magnetic resonance imaging study of synaesthetes and matched controls

PLoS ONE

Volumn 5, Issue 8, 2010, Pages

  van Leeuwen, Tessa M ^a   Petersson, Karl Magnus ^a,b   Hagoort, Peter ^a,b  

^a RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

^b MAX PLANCK INSTITUTE FOR PSYCHOLINGUISTICS   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

OXYGEN;

ADULT; AGED; ARTICLE; BLOOD OXYGENATION; BRAIN FUNCTION; BRAIN REGION; COLOR SYNESTHESIA; COLOR VISION; CONTROLLED STUDY; FEEDBACK SYSTEM; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HUMAN; HYPOTHESIS; MALE; NORMAL HUMAN; OCCIPITAL CORTEX; PARIETAL LOBE; STIMULUS RESPONSE; VISUAL CORTEX; VISUAL DISCRIMINATION; ADOLESCENT; BEHAVIOR; BRAIN; CASE CONTROL STUDY; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOPHYSIOLOGY; PHYSIOLOGY; SENSORY DYSFUNCTION;

ADOLESCENT; ADULT; BEHAVIOR; BRAIN; CASE-CONTROL STUDIES; COLOR PERCEPTION; HUMANS; MAGNETIC RESONANCE IMAGING; SENSATION DISORDERS; YOUNG ADULT;

EID: 77957764154     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0012074     Document Type: Article

References (57)

1. Hochel M, Milán EG (2008) Synaesthesia: The existing state of affairs. Cogn Neuropsychol 25: 93-117.
2. Baron-Cohen S, Wyke MA, Binnie C (1987) Hearing words and seeing colours: an experimental investigation of a case of synaesthesia. Perception 16: 761-767.
3. Wollen KA, Ruggiero FT (1983) Colored-letter synesthesia. J Ment Imagery 7: 83-86.
4. Ramachandran VS, Hubbard EM (2001) Psychophysical investigations into the neural basis of synaesthesia. Proc R Soc London B 268: 979-983.
5. Bargary G, Mitchell KJ (2008) Synaesthesia and cortical connectivity. Trends Neurosci 31: 335-342.
6. Maurer D (1996) Neonatal synaesthesia: implications for the processing of speech and faces. In: Harrison J, Baron-Cohen S, eds. Synaesthesia: Classic and Contemporary Readings. Oxford: Blackwell Publishers. pp 224-242.
7. Smilek D, Dixon MJ, Cudahy C, Merikle PM (2001) Synaesthetic photisms influence visual perception. J Cogn Neurosci 13: 930-936.
8. Grossenbacher PG, Lovelace CT (2001) Mechanisms of synesthesia: cognitive and physiological constraints. Trends Cogn Sci 5: 36-41.
9. Sperling JM, Prvulovic D, Linden DEJ, Singer W, Stirn A (2006) Neuronal correlates of colour-graphemic synaesthesia: a fMRI study. Cortex 42: 295-303.
10. Hubbard EM, Arman AC, Ramachandran VS, Boynton GM (2005) Individual differences among grapheme-color synesthetes: Brain-behavior correlations. Neuron 45: 975-985.
11. Nunn JA, Gregory LJ, Brammer MJ, Williams SCR, Parslow DM, et al. (2002) Functional magnetic resonance imaging of synesthesia: activation of V4/V8 by spoken words. Nat Neurosci 5: 371-375.
12. Rich AN, Williams MA, Puce A, Syngeniotis A, Howard MA, et al. (2006) Neural correlates of imagined and synaesthetic colours. Neuropsychologia 44: 2918-2925.
13. Beeli G, Esslen M, Jancke L (2008) Time course of neural activity correlated with colored-hearing synesthesia. Cereb Cortex 18: 379-385.
14. Weiss PH, Zilles K, Fink GR (2005) When visual perception causes feeling: enhanced cross-modal processing in grapheme-color synesthesia. NeuroImage 28: 859-868.
15. Paulesu E, Harrison J, Baron-Cohen S, Watson JD, Goldstein L, et al. (1995) The physiology of coloured hearing. A PET activation study of colour-word synaesthesia. Brain 118: 661-676.
16. Jäncke L, Beeli G, Eulig C, Hanggi J (2009) The neuroanatomy of graphemecolor synesthesia. Eur J Neurosci 29: 1287-1293.
17. Rouw R, Scholte HS (2007) Increased structural connectivity in grapheme-color synesthesia. Nat Neurosci 10: 792-797.
18. Weiss PH, Fink GR (2009) Grapheme-colour synaesthetes show increased grey matter volumes of parietal and fusiform cortex. Brain 132: 65-70.
19. Hubbard EM (2007) Neurophysiology of synesthesia. Current Psychiatry Reports 9: 193-199.
20. Hubbard EM (2007) A real red-letter day. Nat Neurosci 10: 671-672.
21. Ward J, Li R, Salih S, Sagiv N (2007) Varieties of grapheme-colour synaesthesia: a new theory of phenomenological and behavioural differences. Conscious Cogn 16: 913-931.
22. Robertson LC (2003) Binding, spatial attention and perceptual awareness. Nat Rev Neurosci 4: 93-102.
23. Muggleton N, Tsakanikos E, Walsh V, Ward J (2007) Disruption of synaesthesia following TMS of the right posterior parietal cortex. Neuropsychologia 45: 1582-1585.
24. Esterman M, Verstynen T, Ivry RB, Robertson LC (2006) Coming unbound: disrupting automatic integration of synesthetic color and graphemes by transcranial magnetic stimulation of the right parietal lobe. J Cogn Neurosci 18: 1570-1576.
25. Mattingley JB, Rich AN, Yelland G, Bradshaw JL (2001) Unconscious priming eliminates automatic binding of colour and alphanumeric form in synaesthesia. Nature 410: 580-582.
26. Dixon MJ, Smilek D, Cudahy C, Merikle PM (2000) Five plus two equals yellow. Nature 406: 365.
27. Palmeri TJ, Blake R, Marois R, Flanery MA, Whetsell WJ (2002) The perceptual reality of synesthetic colors. Proc Natl Acad Sci U S A 99: 4127-4131.
28. Kim C-Y, Blake R (2005) Watercolor illusion induced by synesthetic colors. Perception 34: 1501-1507.
29. Kim C-Y, Blake R, Palmeri TJ (2006) Perceptual interaction between real and synesthetic colors. Cortex 42: 195-203.
30. Solomon SG, Lennie P (2007) The machinery of colour vision. Nat Rev Neurosci 8: 276-286.
31. Nikolić D, Lichti P, Singer W (2007) Color opponency in synaesthetic experiences. Psychol Sci 18: 481-486.
32. Dixon MJ, Smilek D, Merikle PM (2004) Not all synaesthetes are created equal: Projector versus associator synaesthetes. Cogn Affect Behav Neurosci 4: 335-343.
33. Edquist J, Rich AN, Brinkman C, Mattingley JB (2006) Do synaesthetic colours act as unique features in visual search? Cortex 42: 222-231.
34. Sagiv N, Heer J, Robertson L (2006) Does binding of synesthetic color to the evoking grapheme require attention? Cortex 42: 232-242.
35. Hong SW, Blake R (2008) Early visual mechanisms do not contribute to synesthetic color experience. Vision Res 48: 1018-1026.
36. Henson RNA (2003) Neuroimaging studies of priming. Prog Neurobiol 70: 53-81.
37. Grill-Spector K, Henson RNA, Martin A (2006) Repetition and the brain: neural models of stimulus-specific effects. Trends Cogn Sci 10: 15-23.
38. Horner AJ, Henson RN (2008) Priming, response learning and repetition suppression. Neuropsychologia 46: 1979-1991.
39. Bartels A, Zeki S (2000) The architecture of the colour centre in the human visual brain: new results and a review. Eur J Neurosci 12: 172-190.
40. McKeefry D, Zeki S (1997) The position and topography of the human colour centre as revealed by functional magnetic resonance imaging. Brain 120: 2229-2242.
41. Beauchamp MS, Haxby JV, Jennings JE, DeYoe EA (1999) An fMRI version of the Farnsworth-Munsell 100-Hue test reveals multiple color-selective areas in human ventral occipitotemporal cortex. Cereb Cortex 9: 257-263.
42. Baron-Cohen S, Harrison J, Goldstein LH, Wyke M (1993) Coloured speech perception: is synaesthesia what happens when modularity breaks down? Perception 22: 419-426.
43. Hubbard EM, Manohar S, Ramachandran VS (2006) Contrast affects the strength of synesthetic colors. Cortex 42: 184-194.
44. Griswold MA, Jakob PM, Heidemann RM, Nittka M, Jellus V, et al. (2002) Generalized autocalibrating partially parallel acquisitions (GRAPPA). Magn Reson Med 47: 1202-1210.
45. Lancaster JL, Rainey LH, Summerlin JL, Freitas CS, Fox PT, et al. (1997) Automated labeling of the human brain: A preliminary report on the development and evaluation of a forward-transform method. Hum Brain Mapp 5: 238-242.
46. Eickhoff SB, Stephan KE, Mohlberg H, Grefkes C, Fink GR, et al. (2005) A new SPM toolbox for combining probabilistic cytoarchitectonic maps and functional imaging data. NeuroImage 25: 1325-1335.
47. Brett M, Anton J-L, Valabregue R, Poline J-B Region of interest analysis using an SPM toolbox [Abstract]; 2002; Sendai, Japan.
48. Dehaene S, Le Clec HG, Poline JB, Le Bihan D, Cohen L (2002) The visual word form area: a prelexical representation of visual words in the fusiform gyrus. Neuroreport 13: 321-325.
49. Pernet C, Celsis P, Demonet JF (2005) Selective response to letter categorization within the left fusiform gyrus. NeuroImage 28: 738-744.
50. Mechelli A, Gorno-Tempini ML, Price CJ (2003) Neuroimaging studies of word and pseudoword reading: Consistencies, inconsistencies, and limitations. J Cogn Neurosci 15: 260-271.
51. Flowers DL, Jones K, Noble K, VanMeter J, Zeffiro TA, et al. (2004) Attention to single letters activates left extrastriate cortex. NeuroImage 21: 829-839.
52. Dehaene S, Cohen L, Sigman M, Vinckier F (2005) The neural code for written words: a proposal. Trends Cogn Sci 9: 335-341.
53. Levy J, Pernet C, Treserras S, Boulanouar K, Berry I, et al. (2008) Piecemeal recruitment of left-lateralized brain areas during reading: A spatio-functional account. NeuroImage 43: 581-591.
54. Kronbichler M, Hutzler F, Wimmer H, Mair A, Staffen W, et al. (2004) The visual word form area and the frequency with which words are encountered: evidence from a parametric fMRI study. NeuroImage 21: 946-953.
55. Garrett AS, Flowers DL, Absher JR, Fahey FH, Gage HD, et al. (2000) Cortical activity related to accuracy of letter recognition. NeuroImage 11: 111-123.
56. Cohen Kadosh R, Cohen Kadosh K, Henik A (2007) The neuronal correlate of bidirectional synesthesia: A combined event-related potential and functional magnetic resonance imaging study. J Cogn Neurosci 19: 2050-2059.
57. Van der Kouwe AJ, Benner T, Fischl B, Schmitt F, Salat DH, et al. (2005) Online automatic slice positioning for brain MR imaging. Neuroimage 27: 222-230.