The testis-specific VAD1.3/AEP1 interacts with β-actin and syntaxin 1 and directs peri-nuclear/Golgi expression with bipartite nucleus localization (BNL) sequence

Biochemical and Biophysical Research Communications

Volumn 401, Issue 2, 2010, Pages 275-280

  Zuo, Yan ^a   Gao, Jing ^a   Yeung, William S B ^a,b   Lee, Kai Fai ^a,b  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Acrosome; Immunoprecipitation; Perinuclei; Spermatogenesis

Indexed keywords

BETA ACTIN; SYNTAXIN 1;

ACROSOME; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CARBOXY TERMINAL SEQUENCE; ENDOPLASMIC RETICULUM; GOLGI COMPLEX; HUMAN; HUMAN CELL; IMMUNOGOLD ELECTRON MICROSCOPY; IMMUNOPRECIPITATION; IN VITRO STUDY; MASS SPECTROMETRY; MOUSE; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; PRIORITY JOURNAL; PROTEIN STRUCTURE; RAT; SPERMATOGENESIS; TESTIS;

ACROSOME; ACTINS; ANIMALS; CELL NUCLEUS; GOLGI APPARATUS; HELA CELLS; HUMANS; MALE; MICE; PROTEINS; RATS; SPERMATOZOA; SYNTAXIN 1; TESTIS;

RATTUS; SUS;

EID: 77957762067     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.09.049     Document Type: Article

References (29)

1. Brucker C., Lipford G.B. The human sperm acrosome reaction, physiology and regulatory mechanisms: an update. Hum. Reprod. Update 1995, 1:51-62.
2. Schill W.B. Some disturbances of acrosomal development and function in human spermatozoa. Hum. Reprod. 1991, 6:969-978.
3. Clermont Y., Xia L., Rambourg A., et al. Structure of the Golgi apparatus in stimulated and nonstimulated acinar cells of mammary glands of the rat. Anat. Rec. 1993, 237:308-317.
4. Abou-Haila A., Tulsiani D.R. Mammalian sperm acrosome: formation, contents, and function. Arch. Biochem. Biophys. 2000, 379:173-182.
5. Ramalho-Santos J., Schatten G., Moreno R.D. Control of membrane fusion during spermiogenesis and the acrosome reaction. Biol. Reprod. 2002, 67:1043-1051.
6. Moreno R.D., Ramalho-Santos J., Chan E.K., et al. The Golgi apparatus segregates from the lysosomal/acrosomal vesicle during rhesus spermiogenesis: structural alterations. Dev. Biol. 2000, 219:334-349.
7. Huang W.P., Ho H.C. Role of microtubule-dependent membrane trafficking in acrosomal biogenesis. Cell Tissue Res. 2006, 323:495-503.
8. Moreno R.D., Palomino J., Schatten G. Assembly of spermatid acrosome depends on microtubule organization during mammalian spermiogenesis. Dev. Biol. 2006, 293:218-227.
9. Luk J.M., Mok B.W., Shum C.K., et al. Identification of novel genes expressed during spermatogenesis in stage-synchronized rat testes by differential display. Biochem. Biophys. Res. Commun. 2003, 307:782-790.
10. Luk J.M., Lee N.P., Shum C.K., et al. Acrosome-specific gene AEP1: identification, characterization and roles in spermatogenesis. J. Cell. Physiol. 2006, 209:755-766.
11. Lee K.F., Tam Y.T., Zuo Y., et al. Characterization of an acrosome protein VAD1.2/AEP2 which is differentially expressed in spermatogenesis. Mol. Hum. Reprod. 2008, 14:465-474.
12. Lee K.F., Xu J.S., Lee Y.L., et al. Demilune cell and parotid protein (Dcpp) from murine oviductal epithelium stimulates pre-implantation embryo development. Endocrinology 2006, 147:79-87.
13. De Kretser D.M., Kerr J.B. The Cytology of the Testis 1988, vol. 1. Raven Press, New York.
14. Kang-Decker N., Mantchev G.T., Juneja SC S.C., et al. Lack of acrosome formation in Hrb-deficient mice. Science 2001, 294:1531-1533.
15. Yao R., Ito C., Natsume Y., et al. Lack of acrosome formation in mice lacking a Golgi protein, GOPC. Proc. Natl. Acad. Sci. USA 2002, 99:11211-11216.
16. Xiao N., Kam C., Shen C., et al. PICK1 deficiency causes male infertility in mice by disrupting acrosome formation. J. Clin. Invest. 2009, 119:802-812.
17. de Wit H. Molecular mechanism of secretory vesicle docking. Biochem. Soc. Trans. 2010, 38:192-198.
18. Rock K.L., Gramm C., RothsteinL L., et al. Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules. Cell 1994, 78:761-771.
19. Lee D.H., Goldberg A.L. Proteasome inhibitors: valuable new tools for cell biologists. Trends Cell Biol. 1998, 8:397-403.
20. Agell N., Mezquita C. Cellular content of ubiquitin and formation of ubiquitin conjugates during chicken spermatogenesis. Biochem. J. 1988, 250:883-889.
21. Roest H.P., Vanklaveren J., Denit J., et al. Inactivation of the HR6B ubiquitin-conjugating DNA-repair enzyme in mice causes male sterility associated with chromatin modification. Cell 1996, 86:799-810.
22. Capoano C.A., Wettstein R., Kun A. Spats 1 (Srsp1) is differentially expressed during testis development of the rat. Gene Expr. Patterns 2010, 10:1-8.
23. Aul R.B., Oko R.J. The major subacrosomal occupant of bull spermatozoa is a novel histone H2B variant associated with the forming acrosome during spermiogenesis. Dev. Biol. 2002, 242:376-387.
24. Berger W., Steiner E., Grusch M., et al. Vaults and the major vault protein: novel roles in signal pathway regulation and immunity. Cell. Mol. Life Sci. 2009, 66:43-61.
25. Gil S., Yosef D., Golan N., et al. The enigma of ATCE1, an acrosome-associated transcription factor. Dev. Biol. 2006, 298:201-211.
26. Lee M.C., Miller E.A., Goldberg J., et al. Bidirectional protein transport between the ER and Golgi. Annu. Rev. Cell Dev. Biol. 2004, 20:87-123.
27. Bethune J., Wieland F., Moelleken J. COPI-mediated transport. J. Membr. Biol. 2006, 211:65-79.
28. Hughes H., Stephens D.J. Assembly, organization and function of the COPII coat. Histochem. Cell Biol. 2008, 129:129-151.
29. Zuzarte M., Rinné S., Schlichthörl G., et al. A di-acidic sequence motif enhances the surface expression of the potassium channel TASK-3. Traffic 2007, 8:1093-1100.