Characterization of an acrosome protein VAD1.2/AEP2 which is differentially expressed in spermatogenesis

Molecular Human Reproduction

Volumn 14, Issue 8, 2008, Pages 465-474

  Lee, Kai Fai ^a   Tam, Yuen Tsung ^a   Zuo, Yan ^a   Cheong, Ana W Y ^a   Pang, Ronald T K ^a   Lee, Nikki P Y ^a   Shum, Cathy K Y ^a   Tam, Po Chor ^a   Cheung, Annie N Y ^a   Yang, Zeng Ming ^b   Yeung, William S B ^a   Luk, John M C ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b XIAMEN UNIVERSITY   (China)

Author keywords

actin; Acrosome; Golgi apparatus; Sermatogenesis; Syntaxin

Indexed keywords

ACROSOME EXPRESSED PROTEIN 2; AMINO ACID; BETA ACTIN; GENE PRODUCT; MESSENGER RNA; MYOSIN HEAVY CHAIN; PROTEIN AEP2; PROTEIN VAD1.2; RETINOL; SYNTAXIN 1;

ACROSOME; ADOLESCENT; ADULT; AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL CYCLE ARREST; CONTROLLED STUDY; CRYPTORCHISM; DIFFERENTIAL DISPLAY; GENE EXPRESSION; GENE IDENTIFICATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOPRECIPITATION; IN VIVO STUDY; MALE; MASS SPECTROMETRY; NONHUMAN; NUCLEOTIDE SEQUENCE; PERINATAL PERIOD; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RAT; RETINOL DEFICIENCY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEMINIFEROUS TUBULE; SEQUENCE HOMOLOGY; SERTOLI CELL; SPERMATID; SPERMATOGENESIS; TESTIS; WESTERN BLOTTING;

ACROSOME; ADOLESCENT; ADULT; AMINO ACID SEQUENCE; ANIMALS; BLOTTING, NORTHERN; BLOTTING, WESTERN; GENE EXPRESSION PROFILING; HUMANS; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; IN SITU HYBRIDIZATION; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; PROTEINS; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY, AMINO ACID; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; SPERMATOGENESIS; TESTIS;

RATTUS; SUIDAE;

EID: 49649113927     PISSN: 13609947     EISSN: 14602407     Source Type: Journal    
DOI: 10.1093/molehr/gan041     Document Type: Article

References (33)

1. Abou-Haila A, Tulsiani DRP. Mammalian sperm acrosome: Formation, contents, and function. Arch Biochem Biophys 2000;379 173-182.
2. Adham IM, Nayernia K, Burkhardt-Gottges E, Topaloglu O, Dixkens C, Holstein AF, Engel W. Teratozoospermia in mice lacking the transition protein 2 (Tnp2). Mol Hum Reprod 2001;7:513-520.
3. Akmal KM, Dufour JM, Vo M, Higginson S, Kim KH. Ligand-dependent regulation of retinoic acid receptor alpha in rat testis: In vivo response to depletion and repletion of vitamin A. Endocrinology 1998;139:1239-1248.
4. Burkhard P, Stetefeld J, Strelkov SV. Coiled coils: A highly versatile protein folding motif. Trends Cell Biol 2001;11:82-88.
5. Cheng CY, Mruk DD. Cell junction dynamics in the testis: Sertoli-germ cell interactions and male contraceptive development. Physiol Rev 2002;82:825-874.
6. Eddy EM, O'Brien DA. The Physiology of Reproduction. Neill JD (ed.). New York: Raven Press, 1994,29-77.
7. Jahn R, Sudhof TC. Membrane fusion and exocytosis. Annu Rev Biochem 1999;68:863-911.
8. Johnson AD, Gomes WR, Vandernark NL. The Testis. Volume 1: Development, Anatomy, and Physiology. New York: Academic Press, 1970.
9. Kang-Decker N, Mantchev GT, Juneja SC, McNiven MA, van Deursen JM. Lack of acrosome formation in Hrb-deficient mice. Science 2001;294 1531-1533.
10. Kierszenbaum AL, Rivkin E, Tres LL. The actin-based motor myosin Va is a component of the acroplaxome, an acrosome-nuclear envelope junctional plate, and of manchette-associated vesicles. Cytogenet Genome Res 2003;103:337-344.
11. Kierszenbaum AL, Tres LL, Rivkin E, Kang-Decker N, van Deursen JM. The acroplaxome is the docking site of Golgi-derived myosin Va/Rab27a/ b-containing proacrosomal vesicles in wild-type and Hrb mutant mouse spermatids. Biol Reprod 2004;70:1400-1410.
12. Lee NPY, Cheng CY. Ectoplasmic specialization, a testis-specific cell-cell actin-based adherens junction type: Is this a potential target for male contraceptive development? Hum Reprod Update 2004;10 349-369.
13. Lee NPY, Cheng CY. Protein kinases and adherens junction dynamics in the seminiferous epithelium of the rat testis. J Cell Physiol 2005; 202:344-360.
14. Lee KF, Chow JF, Xu JS, Chan STH, Ip SM, Yeung WSB. A comparative study of gene expression in murine embryos developed in vivo, cultured in vitro, and cocultured with human oviductal cells using messenger ribonucleic acid differential display. Biol Reprod 2001;64:910-917.
15. Lee KF, Yeung WSB, Chow IF, Shum CK, Luk JM. Different testicular gene expression patterns in the first spermatogenic cycle of postnatal and vitamin A-deficient rat testis. Biol Reprod 2004;70 1010-1017.
16. Lee KF, Xu JS, Lee YL, Yeung WSB. Demilune cell and parotid protein from murine oviductal epithelium stimulates preimplantation embryo development. Endocrinology 2006;147:79-87.
17. Linder B, Bammer S, Heinlein UA. Delayed translation and posttranslational processing of cyritestin, an integral transmembrane protein of the mouse acrosome. Exp Cell Res 1995;221:66-72.
18. Luk JM, Mok BW, Shum CK, Yeung WSB, Tam PC, Tse JY, Chow JF, Woo J, Kam K, Lee KF. Identification of novel genes expressed during spermatogenesis in stage-synchronized rat testes by differential display. Biochem Biophys Res Commun 2003;307:782-790.
19. Luk JM, Lee NP, Shum CK, Lam BY, Siu AF, Che CM, Tam PC, Cheung AN, Yang ZM, Lin YN et al. Acrosome-specific gene AEP1: Identification, characterization and roles in spermatogenesis. J Cell Physiol 2006;209:755-766.
20. Lupas A, Van Dyke M, Stock J. Predicting coiled coils from protein sequences. Science 1991;252:1162-1164.
21. Maekawa M, Toyama Y, Yasuda M, Yagi T, Yuasa S. Fyn tyrosine kinase in Sertoli cells is involved in mouse spermatogenesis. Biol Reprod 2002;66:211-221.
22. Mitranond V, Sobhon P, Tosukhowong P, Chindaduangrat W. Cytological changes in the testes of vitamin-A-deficient rats. I. Quantitation of germinal cells in the seminiferous tubules. Acta Anal (Basel) 1979;103:159-168.
23. Morales C, Griswold MD. Retinol-induced stage synchronization in seminiferous tubules of the rat. Endocrinology 1987;121 432-434.
24. Mruk DD, Cheng CY. Sertoli-Sertoli and Sertoli-germ cell interactions and their significance in germ cell movement in the seminiferous epithelium during spermatogenesis. Endocr Rev 2004;25 747-806.
25. Napoli JL. Retinoic acid biosynthesis and metabolism. FASEB J 1996;10: 993-1001.
26. Ramalho-Santos J, Schatten G, Moreno RD. Control of membrane fusion during spermiogenesis and the acrosome reaction. Biol Reprod 2002;67:1043-1051.
27. Russell L, Ettlin RA, Sinha-Hikim AP, Clegg EJ. Histological and histopathological evaluation of the testis. Clearwater, FL: Cache River, 1990,1-52.
28. Tomes CN, Michaut M, De Blas G, Visconti P, Matti U, Mayorga LS. SNARE complex assembly is required for human sperm acrosome reaction. Dev Biol 2002;243:326-338.
29. Unni E, Rao MR, Ganguly J. Histological and ultrastructural studies on the effect of vitamin A depletion & subsequent repletion with vitamin A on germ cells and Sertoli cells in rat testis. Indian J Exp Biol 1983;21:180-192.
30. van Pelt AM, de Rooij DG. Retinoic acid is able to reinitiate spermatogenesis in vitamin-A-deficient rats and high replicate doses support the full development of spermatogenic cells. Endocrinology 1991;128:697-704.
31. White JC, Highland M, Kaiser M, Clagett-Dame M. Vitamin A deficiency results in the dose-dependent acquisition of anterior character and shortening of the caudal hindbrain of the rat embryo. Dev Biol 2000;220:263-284.
32. Wine RN, Chapin RE. Adhesion and signaling proteins spatiotemporally associated with spermiation in the rat. J Androl 1999;20 198-213.
33. Yao R, Ito C, Natsume Y, Sugitani Y, Yamanaka H, Kuretake S, Yanagida K, Sato A, Toshimori K, Noda T. Lack of acrosome formation in mice lacking a Golgi protein, GOPC. Proc Natl Acad Sci USA 2002;99 11211-11216.