Minimization, by its nature, precludes allocation concealment, and invites selection bias

Contemporary Clinical Trials

Volumn 31, Issue 5, 2010, Pages 406-

  Berger, Vance W ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Allocation concealment; Clinical trial; Masking; Minimization; Selection bias

Indexed keywords

CHRONOLOGY; EPIDEMIOLOGICAL DATA; LETTER; PROBABILITY; RANDOMIZATION;

ALGORITHMS; CLINICAL TRIALS AS TOPIC; DATA COLLECTION; DATA INTERPRETATION, STATISTICAL; HUMANS; PATIENT SELECTION; RANDOM ALLOCATION; RESEARCH DESIGN; RESEARCH SUBJECTS; SELECTION BIAS;

EID: 77957756213     PISSN: 15517144     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cct.2010.05.001     Document Type: Letter

References (4)

1. Taves D.R. The use of minimization in clinical trials. Contemp Clin Trials 2010, 31:180-184.
2. Berger V.W. Selection bias and covariate imbalances in randomized clinical trials 2005, John Wiley & Sons, Chichester.
3. Berger V.W., Ivanova A., Deloria-Knoll M. Minimizing predictability while retaining balance through the use of less restrictive randomization procedures. Stat Med 2003, 22(19):3017-3028.
4. Berger V.W., Grant W.C., Vazquez LF. "Sensitivity designs for preventing bias replication in randomized clinical trials". Stat Med Res 2010, 19:4415-4424.