YKL-40 protein levels and clinical outcome of human endometrial cancer

Journal of International Medical Research

Volumn 38, Issue 4, 2010, Pages 1448-1457

  Peng, C ^a   Peng, J ^a   Jiang, L ^a   You, Q ^a   Zheng, J ^a   Ning, X ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

Endometrial cancer; Immunohistochemistry; Overall survival; Prognosis; Progression free survival; YKL 40

Indexed keywords

GLYCOPROTEIN; PROTEIN YKL 40; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CANCER GRADING; CANCER INVASION; CANCER STAGING; CANCER SURVIVAL; CLINICAL ASSESSMENT; CONTROLLED STUDY; ENDOMETRIUM CARCINOMA; ENDOMETRIUM HYPERPLASIA; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; LYMPH VESSEL; OVERALL SURVIVAL; PREDICTION; PROGNOSIS; PROGRESSION FREE SURVIVAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION;

EID: 77957738887     PISSN: 03000605     EISSN: None     Source Type: Journal    
DOI: 10.1177/147323001003800427     Document Type: Article

References (30)

1. Jemal A, Siegel R, Ward E, et al: Cancer statistics, 2008. CA Cancer J Clin 2008; 58: 71-96.
2. Lotocki RJ, Copeland LJ, DePetrillo AD, et al: Stage I endometrial adenocarcinoma: treatment results in 835 patients. Am J Obstet Gynecol 1983; 146: 141-145.
3. Fujimoto T, Nanjyo H, Fukuda J, et al: Endometrioid uterine cancer: histopathological risk factors of local and distant recurrence. Gynecol Oncol 2009; 112: 342-347.
4. Hecht J, Mutter GL: Molecular and pathologic aspects of endometrial carcinogenesis. J Clin Oncol 2006; 24: 4783-4791.
5. Johansen JS, Williamson MK, Rice JS, et al: Identification of proteins secreted by human osteoblastic cells in culture. J Bone Miner Res 1992; 7: 501-512.
6. Shackelton LM, Mann DM, Millis AJ: Identification of a 38-kDa heparin binding glycoprotein (gp38k) in differentiating vascular smooth muscle cells as a member of a group of proteins associated with tissue remodeling. J Biol Chem 1995; 270: 13076-13083.
7. Badariotti F, Kypriotou M, Lelong C, et al: The phylo-genetically conserved molluscan chitinase-like protein 1 (Cg-Clp1), homologue of human HC-gp39, stimulates proliferation and regulates synthesis of extracellular matrix components of mammalian chondrocytes. J Biol Chem 2006; 281: 29583-29596.
8. Johansen JS: Studies on serum YKL-40 as a biomarker in diseases with inflammation, tissue remodelling, fibroses and cancer. Dan Med Bull 2006; 53: 172-209.
9. Johansen JS, Christensen IJ, Riisbro R, et al: High serum YKL-40 levels in patients with primary breast cancer is related to short recurrence free survival. Breast Cancer Res Treat 2003; 80: 15-21.
10. Mitsuhashi A, Matsui H, Usui H, et al: Serum YKL-40 as a marker for cervical adenocarcinoma. Ann Oncol 2009; 20: 71-77.
11. Yang GF, Cai PY, Li XM, et al: Expression and clinical significance of YKL-40 protein in epithelial ovarian cancer tissues. Ai Zheng 2009; 28: 142-145.
12. Høgdall EV, Ringsholt M, Høgdall CK, et al: YKL-40 tissue expression and plasma levels in patients with ovarian cancer. BMC Cancer 2009; 9: 8.
13. Johansen JS, Drivsholm L, Price PA, et al: High serum YKL-40 level in patients with small cell lung cancer is related to early death. Lung Cancer 2004; 46: 333-340.
14. Schmidt H, Johansen JS, Gehl J, et al: Elevated serum level of YKL-40 is an independent prognostic factor for poor survival in patients with metastatic melanoma. Cancer 2006; 106: 1130-1139.
15. Kim SH, Das K, Noreen S, et al: Prognostic implications of immunohisto-chemically detected YKL-40 expression in breast cancer. World J Surg Oncol 2007; 5: 17.
16. Roslind A, Knoop AS, Jensen MB, et al: YKL-40 protein expression is not a prognostic marker in patients with primary breast cancer. Breast Cancer Res Treat 2008; 112: 275-285.
17. Diefenbach CS, Shah Z, Iasonos A, et al: Preoperative serum YKL-40 is a marker for detection and prognosis of endometrial cancer. Gynecol Oncol 2007; 104: 435-442.
18. Zaino RJ, Kurman RJ, Diana KL, et al: The utility of the revised International Federation of Gynecology and Obstetrics histologic grading of endometrial adenocarcinoma using a defined nuclear grading system. Cancer 1995; 75: 81-86.
19. FIGO Cancer Committee: Announcements: FIGO stages-1988 revision. Gynecol Oncol 1989; 35: 125-127.
20. Pelloski CE, Mahajan A, Maor M, et al: YKL-40 expression is associated with poorer response to radiation and shorter overall survival in glioblastoma. Clin Cancer Res 2005; 11: 3326-3334.
21. Recklies AD, White C, Ling H: The chitinase 3-like protein human cartilage glycoprotein 39 (HC-gp39) stimulates proliferation of human connective tissue cells and activates both extracellular signal-regulated kinase-and protein kinase B-mediated signaling pathways. J Biochem 2002; 365: 119-126.
22. Malinda KM, Ponce L, Kleinman HK, et al: Gp38k, a protein synthesized by vascular smooth muscle cells, stimulates directional migration of human umbilical vein endothelial cells. Exp Cell Res 1999; 250: 168-173.
23. Nishikawa KC, Millis AJ: gp38k (CHI3L1) is a novel adhesion and migration factor for vascular cells. Exp Cell Res 2003; 287: 79-87.
24. Nigro JM, Misra A, Zhang L, et al: Integrated array-comparative genomic hybridization and expression array profiles identify clinically relevant molecular subtypes of glioblastoma. Cancer Res 2005; 65: 1678-1686.
25. Bi J, Lau SH, Lv ZL, et al: Overexpression of YKL-40 is an independent prognostic marker in gastric cancer. Hum Pathol 2009; 40: 1790-1797.
26. Shao R, Hamel K, Petersen L, et al: YKL-40, a secreted glycoprotein, promotes tumor angiogenesis. Oncogene 2009; 28: 4456-4468.
27. Junker N, Johansen JS, Hansen LT, et al: Regulation of YKL-40 expression during genotoxic or micro-environmental stress in human glioblastoma cells. Cancer Sci 2005; 96: 183-190.
28. Bigg HF, Wait R, Rowan AD, et al: The mammalian chitinase-like lectin, YKL-40, binds specifically to type I collagen and modulates the rate of type I collagen fibril formation. J Biol Chem 2006; 281: 21082-21095.
29. Fusetti F, Pijning T, Kalk KH, et al: Crystal structure and carbohydrate-binding properties of the human cartilage glycoprotein-39. J Biol Chem 2003; 278: 37753-37760.
30. Roslind A, Johansen JS, Christensen IJ, et al: High serum levels of YKL-40 in patients with squamous cell carcinoma of the head and neck are associated with short survival. Int J Cancer 2008; 122: 857-863.