Extracts from Rhizopus oryzae KSD-815 of Korean traditional nuruk confer the potential to inhibit hypertension, platelet aggregation, and cancer metastasis in vitro

Food Science and Biotechnology

Volumn 18, Issue 6, 2009, Pages 1423-1429

  Lee, Sang Jin ^a,c   Bae, Hyun Jin ^a   Ryu, Jiyeon ^a   Lee, Daeyoung ^b   Kim, Gye Won ^c   Baek, Namin ^b   Kwon, Moosik ^a   Hong, Sungyoul ^a  

^a Sungkyunkwan University   (South Korea)

^b Kyung Hee University   (South Korea)

^c Kooksoondang Brewery Co Ltd   (South Korea)

Author keywords

Anti hypertension; Anti metastatic activity; Korean traditional nuruk; Platelet aggregation; Rhizopus oryzae KSD 815

Indexed keywords

ANTI-HYPERTENSION; ANTI-METASTATIC ACTIVITY; KOREAN TRADITIONAL NURUK; PLATELET AGGREGATION; RHIZOPUS ORYZAE;

CELLS; DISEASES; HEXANE; PATHOLOGY; PLATELETS;

CELL CULTURE;

RHIZOPUS ORYZAE;

EID: 77957737503     PISSN: 12267708     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Agli MD, Busciala A, Bosisio E. Vascular effects of wine polyphenols. Cardiovasc. Res. 63: 593-602 (2004)
2. Renaud S, de Lorgeril M. Wine, alcohol, platelets, and the French paradox for coronary artery disease. Lancet 339: 1523-1526 (1992)
3. Tunstall-Pedoe H, Kuulasmaa K, Mahonen M, Tolonen H, Ruokokoski E, Amouyel P. Contribution of trends in survival and coronary-event rates to changes in coronary heart disease mortality: 10-years results from 37 WHO MONICA project populations: Monitoring trends and determinants in cardiovascular disease. Lancet 353: 1547-1557 (1999)
4. Shon SK, Rho YH, Kim HJ, Bae SM. Takju brewing of uncooked rice starch using Rhizopus koji. Korean J. Appl. Microbiol. Biotechnol. 18: 506-510 (1990)
5. Yu TS, Yeo SH, Kim HS. A new species of hypmycetes, coreanus sp. nov., isolated from traditional Korean nuruk. J. Microbiol. Biotechn. 14: 182-187 (2004)
6. Jeon BY, Kim SJ, Kim DH, Na BK, Park DH, Tran HT, Zhang R, Ahn DH. Development of a serial bioreactor system for direct ethanol production from starch using Aspergillus niger and Saccharomyces cerevisiae. Biotechnol. Bioprocess Eng. 12: 566-573 (2007)
7. Yoon CG, Chae SN, Huh NE, Kim HS, Yu TS. Effects of nuruk or wheat bran supplemented diet on the serum levels of cholesterol and activities of hepatic oxygen free radical metabolizing enzymes rats. J. Korean Soc. Food Sci. Nutr. 28: 212-217 (1999)
8. Jung H, Kang JC. Documental studies on anti-cancer therapy by using medi-alcohol. J. Korean Oncol. 5: 119-136 (1999)
9. Kim HR, Ahn BH. Research trend of Korean traditional alcoholic beverage. Food Ind. Nutr. 6: 5-10 (2001)
10. Lee SJ, Kwon YJ, Kim HR, Ahn BH. Chemical and sensory characterization of Korean commercial rice wines (yakju). Food Sci. Biotechnol. 16: 374-380 (2007)
11. Kim JH, Lee DH, Choi SY, Lee JS. Characterization of physiological functionalities in Korean traditional liquors. Korean J. Food Sci. Technol. 34: 118-122 (2002)
12. Kim JH, Lee JH, Kim HJ, Choi SY, Lee JS. Effects of barley koji and legumes on the quality and fibrinolytic activity of Korean traditional rice wine. J. Korean Soc. Food Sci. Nutr. 32: 1066-1070 (2003)
13. Kim JH, Jeong SC, Kim NM, Lee JS. Effect of Indian millet koji and legumes on the quality and angiotensin I-converting enzyme inhibitor activity of Korean traditional rice wine. Korean J. Food Sci. Technol. 35: 733-737 (2003)
14. Chung HS, Hong SH, Do KR, Rhee HK, Jung SK, Hwang WJ, Kim HM. MooPoong (Gye Young Jeong) increases HDL- cholesterol but decreases LDL cholesterol and body weight. Immunopharm. Immunot. 26: 225-232 (2004)
15. Chung KS, Oh WT, Nam SM, Son BS, Park YS. Effect off Korean rice-wine (yakju) on in vitro and in vivo progression of B16BL6 mouse melanoma and HRT18 human colon adenocarcinoma cells. Korean J. Food Sci. Technol. 30: 1470-1475 (1998)
16. Kim SJ, Ko SH, Lee WY, Kim GW. Cytotoxic effects of Korean rice-wine (yakju) on cancer cells. Korean J. Food Sci. Technol. 36: 812-817 (2004)
17. Kim SJ, Baek JY, Park CK, Kim GW. Gastroprotective effect of Korean rice-wine (yakju). Korean J. Food Sci. Technol. 36: 818-822 (2004)
18. Cushman DW, Cheung HS. Spectrophotometric assay and properties of the angiotensin-converting enzyme of rabbit lung. Biochem. Pharmacol. 20: 1637-1648 (1971)
19. Born GV, Cross MJ. The aggregation of blood platelets. J. Physiol. 168: 178-195 (1963)
20. Oikawa T, Hirotani K, Nakamura O, Shudo K, Hiragun A, Iwaguchi T. A highly potent antiangiogenic activity of retinoids. Cancer Lett. 48: 157-162 (1998)
21. Li GH, Liu H, Shi YH, Le GW. Direct spectrophotometric measurement of angiotensin I-converting enzyme inhibitory activity for screening bioactive peptides. J. Pharmaceut. Biomed. 37: 219-224 (2005)
22. Das UN. Essential fatty acids and their metabolites could function as endogenous HMG-CoA reductase and ACE enzyme inhibitors, anti-arrhythmic, anti-hypertensive, anti-atherosclerotic, and anti- inflammatory, cytoprotective, and cardioprotective molecules. Lipids Health Dis. 15: 7-37 (2008)
23. Oqawa A, Suzuk Y, Aoyama T, Takeuchi H. Dietary alpha-linoleic acid inhibits angiotensin-converting enzyme activity and mRNA expression levels in the aorta of spontaneously hypertensive rats. J. Oleo Sci. 58: 355-360 (2009)
24. Frarndale RW, Sixma JJ, Barnes MJ, De Groot PG. The role of collagen in thrombosis and hemostasis. J. Thromb. Haemost. 2: 561-573 (2004)
25. Sarratt KL, Chen H, Zutter MM, Santoro SA, Hammer DA, Kahn ML. GPVI and α2β1 play independent critical roles during platelet adhesion and aggregate formation to collagen under flow. Blood 106: 1268-1277 (2005)
26. Jackson SP, Nesbitt WS, Kulkarni S. Signaling events underlying thrombus formation. J. Thromb. Haemost. 1: 1602-1612 (2003)
27. Emms H, Lewis GP. The role of prostaglandin endoperoxides, thromboxane A2, and adenosine diphosphate in collagen-induced aggregation in man and the rat. Brit. J. Pharmacol. 87: 109-115 (1986)
28. Hu K, Liu Q, Wang S, Ding K. New oligosaccharides prepared by acid hydrolysis of the polysaccharides from Nerium indicum Mill and their anti-angiogenesis activities. Carbohyd. Res. 26: 198-203 (2009)
29. Ma J, Xin X, Meng L, Tong L, Lin L, Geng M, Ding J. The marine- derived oligosaccharide sulfate (MdOS), a novel multiple tyrosine kinase inhibitor, combats tumor angiogenesis both in vitro and in vivo. PloS One 3: e3774 (1-11) (2008)
30. Cole CL, Jayson GC. Oligosaccharides as anti-angiogenic agents. Expert Opin. Biol. Th. 8: 351-362 (2008)
31. Jubb AM, Pham TQ, Handy AM, Frantz GD, Peale FV, Wu TD, Koeppen HW, Hillan KJ. Expression of vascular endothelial growth factor, hypoxia inducible factor 1α, and carbonic anhydrase IX in human tumours. J. Clin. Pathol. 57: 504-512 (2004)
32. Shi YH, Bingle L, Gong LH, Wang YX, Corke KP, Fang WG. Basic FGF augments hypoxia induced HIF-1-α expression and VEGF release in T47D breast cancer cells. Pathology 39: 396-400 (2007)
33. Hellwig-Bürgel T, Stiehl DP, Wagner AE, Metzen E, Jelkmann W. Hypoxia-inducible factor-1 (HIF-1): A novel transcription factor in immune reactions. J. Interf. Cytok. Res. 25: 297-310 (2005)