β-Globin gene cluster haplotypes in a cohort of 221 children with sickle cell anemia or Sβ-thalassemia and their association with clinical and hematological features

Acta Haematologica

Volumn 124, Issue 3, 2010, Pages 162-170

  Belisário, André Rolim ^a,d   Martins, Marina Lobato ^d   Brito, Ana Mercy Siebra ^b,d   Rodrigues, Cibele Velloso ^c,d   Silva, Célia Maria ^d   Viana, Marcos Borato ^a  

^a Medical School/NUPAD   (Brazil)

^b FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^c Pontificial Catholic University of Minas Gerais   (Brazil)

^d Hemominas Foundation   (Brazil)

Author keywords

Globin gene; Clinical genetics; Haplotypes; Hemoglobinopathies; Pediatric hematology; Prognosis; Sickle cell anemia

Indexed keywords

BETA GLOBIN; HEMOGLOBIN; HEMOGLOBIN F;

ACUTE CHEST SYNDROME; ARTICLE; BLOOD TRANSFUSION; CEREBROVASCULAR DISEASE; CHILD; CLINICAL FEATURE; CLINICAL TRIAL; COHORT ANALYSIS; CONTROLLED CLINICAL TRIAL; DISEASE ASSOCIATION; DOPPLER ECHOGRAPHY; FEMALE; GENE CLUSTER; GENOTYPE; HAPLOTYPE; HEMOGLOBIN BLOOD LEVEL; HIGH RISK PATIENT; HUMAN; LEUKOCYTE COUNT; MAJOR CLINICAL STUDY; MALE; MEAN CORPUSCULAR HEMOGLOBIN; MEAN CORPUSCULAR VOLUME; NEWBORN SCREENING; POLYMERASE CHAIN REACTION; PRESCHOOL CHILD; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RETICULOCYTE COUNT; RETROSPECTIVE STUDY; SCHOOL CHILD; SICKLE CELL BETA THALASSEMIA; STROKE;

ANEMIA, SICKLE CELL; BASE SEQUENCE; BETA-GLOBINS; BETA-THALASSEMIA; BRAZIL; CHILD; CHILD, PRESCHOOL; COHORT STUDIES; DNA PRIMERS; FEMALE; GENE FREQUENCY; HAPLOTYPES; HEMOGLOBIN, SICKLE; HUMANS; INFANT; MALE; MULTIGENE FAMILY; RETROSPECTIVE STUDIES;

EID: 77957734926     PISSN: 00015792     EISSN: None     Source Type: Journal    
DOI: 10.1159/000320271     Document Type: Article

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