Four new cases of double heterozygosity for BRCA1 and BRCA2 gene mutations: Clinical, pathological, and family characteristics

Breast Cancer Research and Treatment

Volumn 124, Issue 1, 2010, Pages 251-258

  Zuradelli, Monica ^a   Peissel, Bernard ^b   Manoukian, Siranoush ^b   Zaffaroni, Daniela ^b   Barile, Monica ^c   Pensotti, Valeria ^d   Cavallari, Ugo ^a   Masci, Giovanna ^a   Mariette, Frederique ^d   Benski, Anne Caroline ^a   Santoro, Armando ^a   Radice, Paolo ^b,e  

^a HUMANITAS CLINICAL AND RESEARCH CENTER   (Italy)

^b NATIONAL CANCER INSTITUTE   (Italy)

^c EUROPEAN INSTITUTE OF ONCOLOGY   (Italy)

^d Consortium for Genomics Technology ^*  (Italy)

^e FIRC INSTITUTE OF MOLECULAR ONCOLOGY   (Italy)

Author keywords

BRCA1; BRCA2; Cancer susceptibility; Double heterozygosity; Genetic counseling

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN; CARBOPLATIN; CYCLOPHOSPHAMIDE; DOXORUBICIN; FLUOROURACIL; GENOMIC DNA; METHOTREXATE; PACLITAXEL; TAMOXIFEN;

ADULT; ARTICLE; BREAST CANCER; BREAST CARCINOMA; CANCER COMBINATION CHEMOTHERAPY; CANCER HORMONE THERAPY; CANCER RADIOTHERAPY; CANCER SURGERY; CARCINOGENESIS; CASE REPORT; FEMALE; GENE MUTATION; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC COUNSELING; GENETIC SUSCEPTIBILITY; HEREDITY; HETEROZYGOSITY; HUMAN; HUMAN TISSUE; HYSTERECTOMY; LYMPHADENECTOMY; MAMMOGRAPHY; MULTIPLE CYCLE TREATMENT; OMENTECTOMY; OVARY CANCER; OVARY CARCINOMA; PARTIAL MASTECTOMY; PHENOTYPE; PRIORITY JOURNAL; SALPINGOOOPHORECTOMY; TUMOR BIOPSY;

ADULT; BRCA1 PROTEIN; BRCA2 PROTEIN; BREAST NEOPLASMS; FEMALE; GENETIC COUNSELING; GENETIC PREDISPOSITION TO DISEASE; HEREDITY; HETEROZYGOTE; HUMANS; ITALY; MIDDLE AGED; MUTATION; OVARIAN NEOPLASMS; PEDIGREE; PHENOTYPE; TREATMENT OUTCOME;

EID: 77957714920     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-010-0853-8     Document Type: Article

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