Treatment and eradication of murine fur mites: I. Toxicologic evaluation of ivermectin-compounded feed

Journal of the American Association for Laboratory Animal Science

Volumn 49, Issue 5, 2010, Pages 564-570

  Ricart Arbona, Rodolfo J ^a,b   Lipman, Neil S ^a,b   Riedel, Elyn R ^b   Wolf, Felix R ^a,b  

^a ROCKEFELLER UNIVERSITY   (United States)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IVERMECTIN;

ANIMAL EXPERIMENT; ANIMAL FOOD; ANIMAL MODEL; ARTICLE; ATAXIA; BLOOD SAMPLING; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG STABILITY; FEMALE; FERTILITY; GAMMA IRRADIATION; MALE; MITE; MITE INFESTATION; MOUSE; NONHUMAN; ORGANISM COLONY; STATISTICAL ANALYSIS; TOXICITY TESTING; TREMOR;

ANIMALS; ANTIPARASITIC AGENTS; BODY WEIGHT; FEMALE; HAIR; IVERMECTIN; MALE; MICE; MICE, INBRED C57BL; MITE INFESTATIONS; MITES; RODENT DISEASES; TOXICITY TESTS;

ACARI; ANIMALIA; MURINAE; MUS; MYOCOPTES; RODENTIA;

EID: 77957698729     PISSN: 15596109     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (41)

1. Altholtz LY, La Perle KM, Quimby FW. 2006. Dose-dependant hypothyroidism in mice induced by commercial trimethoprimsulfamethoxazole rodent feed. Comp Med 56:395-401.
2. Bachmanov AA, Reed DR, Beauchamp GK, Tordoff MG. 2002. Food intake, water intake, and drinking spout side preference of 28 mouse strains. Behav Genet 32:435-443.
3. Baumans V, Havenaar R, van Herck H. 1988. The use of repeated treatment with Ivomec and Neguvon spray in the control of murine fur mites and oxyurid worms. Lab Anim 22:246-249.
4. Baumans V, Havenaar R, van Herck H, Rooymans TP. 1988. The effectiveness of Ivomec and Neguvon in the control of murine mites. Lab Anim 22:243-245.
5. Bissonnette S, Paradis M, Daneau I, Silversides DW. 2009. The ABCB1 1δ mutation is not responsible for subchronic neurotoxicity seen in dogs of noncollie breeds following macrocyclic lactone treatment for generalized demodicosis. Vet Dermatol 20:60-66.
6. Blakley BR, Rousseaux CG. 1991. Effect of ivermectin on the immune response in mice. Am J Vet Res 52:593-595.
7. Burdett EC, Heckmann RA, Ochoa R. 1997. Evaluation of 5 treatment regimens and 5 diagnostic methods for murine mites (Myocoptes musculinus and Myobia musculi). Contemp Top Lab Anim Sci 36:73-76.
8. Carty AJ. 2008. Opportunistic infections of mice and rats: Jacoby and Lindsey revisited. ILAR J 49:272-276.
9. Conole J, Wilkinson MJ, McKellar QA. 2003. Some observations on the pharmacological properties of ivermectin during treatment of a mite infestation in mice. Contemp Top Lab Anim Sci 42:42-45.
10. Davis JA, Paylor R, McDonald MP, Libbey M, Ligler A, Bryant K, Crawley JN. 1999. Behavioral effects of ivermectin in mice. Lab Anim Sci 49:288-296.
11. Flynn BM, Brown PA, Eckstein JM, Strong D. 1989. Treatment of Syphacia obvelata in mice using ivermectin. Lab Anim Sci 39:461-463.
12. Gaertner DJ. 2004. Speculations on why some lab rodent pathogens continue to be prevalent. Contemp Top Lab Anim Sci 43:8.
13. Gönenç B, Sarimehmetoǧlu HO, Iça A, Kozan E. 2006. Efficacy of selamectin against mites (Myobia musculi, Mycoptes musculinus and Radfordia ensifera) and nematodes (Aspiculuris tetraptera and Syphacia obvelata) in mice. Lab Anim 40:210-213.
14. Huerkamp MJ, Zitzow LA, Webb S, Pullium JK. 2005. Cross-fostering in combination with ivermectin therapy: a method to eradicate murine fur mites. Contemp Top Lab Anim Sci 44:12-16.
15. Institute for Laboratory Animal Research. 1996. Guide for the care and use of laboratory animals. Washington (DC): National Academies Press.
16. Jacoby RO, Fox JG, Davissen M. Biology and diseases of mice. In: Fox JG, Anderson LC, Loew FM, Quimby FW, editors. Laboratory animal medicine, 2nd ed. Orlando (FL): Academic Press.
17. Jacoby RO, Lindsey JR. 1998. Risks of infection among laboratory rats and mice at major biomedical research institutions. ILAR J 39:266-271.
18. Johnston NA, Trammell RA, Ball-Kell S, Verhulst S, Toth LA. 2009. Assesment of immune function in mice before and after eradication of mite infestation. J Am Assoc Lab Anim Sci 48:371-377.
19. Klement P, Augustine JM, Delaney KH, Klement G, Weitz JI. 1996. An oral ivermectin regimen that eradicates pinworms (Syphacia spp.) in laboratory rats and mice. Lab Anim Sci 46:286-290.
20. Lankas GR, Cartwright ME, Umbenhauer D. 1997. P-glycoprotein deficiency in a subpopulation of CF1 mice enhances avermectin-induced neurotoxicity. Toxicol Appl Pharmacol 143:357-365. (Pubitemid 27183553)
21. Lankas GR, Gordon LR. Toxicology. In: Campbell WC, editor. Ivermectin and abamectin. New York (NY): Springer-Verlag.
22. Lankas GR, Wise LD, Cartwright ME, Pippert T, Umbenhauer DR. 1998. Placental P-glycoprotein deficiency enhances susceptibility to chemically induced birth defects in mice. Reprod Toxicol 12:457-463. (Pubitemid 29110878)
23. Levee EM, Klinger MM, Kaiser CC, Serrano LJ. 1994. A practical delivery method for oral administration of ivermectin to large colonies of rodents. Contemp Top Lab Anim Sci 33:68-70.
24. Lipman NS, Dalton SD, Stuart AR, Arruda K. 1994. Eradication of pinworms (Syphacia obvelata) from a large mouse breeding colony by combination oral anthelmintic therapy. Lab Anim Sci 44:517-520.
25. McIntyre AR, Lipman NS. 2007. Amoxicillin-clavulanic acid and trimethoprim- sulfamethoxazole in rodent feed and water: effects of compounding on antibiotic stability. J Am Assoc Lab Anim Sci 46:26-32.
26. Mook DM, Benjamin KA. 2008. Use of selamectin and moxidectin in the treatment of mouse fur mites. J Am Assoc Lab Anim Sci 47:20-24.
27. Moore TD, Horton R, Utrup LJ, Miller LA, Poupard JA. 1996. Stability of amoxicillin-clavulanate in BACTEC medium determined by high-performance liquid chromatography and bioassay. J Clin Microbiol 34:1321-1322. (Pubitemid 26126920)
28. Papini R, Marconcini A. 1991. Treatment with ivermectin in drinking water against Myobia musculi and Myocoptes musculinus mange in naturally infected laboratory mice. Angew Parasitol 32:11-13.
29. Pollicino P, Rossi L, Rambozzi L, Farca AM, Peano A. 2007. Oral administration of moxidectin for treatment of murine acariosis due to Radfordia affinis. Vet Parasitol 151:355-357.
30. Ricart Arbona RJ, Lipman NS, Wolf F. 2010. Murine fur mite treatment and eradication III. Treatment of a large mouse colony with ivermectin-compounded feed. J Am Assoc Lab Anim Sci 49:633-637.
31. Schinkel AH, Smit JJ, van Tellingen O, Beijnen JH, Wagenaar E, van Deemter L, Mol CA, van der Valk MA, Robanus-Maandag EC, te Riele HP, Berns AJM, Borst P. 1994. Disruption of the mouse Mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs. Cell 77:491-502.
32. Silverman J, Blatt H, Lerro A. 1983. Effect of ivermectin against Myobia musculi. Lab Anim Sci 33:487.
33. Skopets B, Wilson RP, Griffith JW, Lang CM. 1996. Ivermectin toxicity in young mice. Lab Anim Sci 46:111-112.
34. Support TFT. Taconic inquiry response 7.7.09.
35. Takano N, Arai I, Kurachi M. 2006. A method to induce stable atopic dermatitis-like symptoms in NC/Nga mice housed with skin-lesioned mice. Br J Dermatol 154:426-430.
36. Toth LA, Oberbeck C, Straign CM, Frazier S, Rehg JE. 2000. Toxicity evaluation of prophylactic treatments for mites and pinworms in mice. Contemp Top Lab Anim Sci 39:18-21.
37. Turner MJ, Schaeffer JM. Mode of action of ivermectin. In: Campbell WC, editor. Ivermectin and abamectin. New York (NY): Springer-Verlag.
38. Valvo L, Manna L, Alimenti R, Alimonti S, Bertocchi P, Ciranni E. 1999. Amoxicillin sodium-potassium clavulanate: evaluation of γ-radiation- induced effects by liquid chromatography on both the individual drugs and their combination. J Pharm Biomed Anal 21:9-14. (Pubitemid 29430137)
39. Watson DP. 1961. The effect of the mite Myocoptes musculinus (CL Koch 1840) on the skin of the white laboratory mouse and its control. Parasitology 51:373-378.
40. Whiteley HJ, Horton DL. 1965. Further observations on the effect of Myobia musculi on the skin of the mouse. J Pathol Bacteriol 89:331-335.
41. Wing SR, Courtney CH, Young MD. 1985. Effect of ivermectin on murine mites. J Am Vet Med Assoc 187:1191-1192.