An oral ivermectin regimen that eradicates pinworms (Syphacia spp.) in laboratory rats and mice

Laboratory Animal Science

Volumn 46, Issue 3, 1996, Pages 286-290

  Klement, Petr ^b   Augustine, Janet M ^a   Delaney, Kathleen H ^a   Klement, Giannoula ^b   Weitz, Jeffrey I ^a,b,c  

^a MCMASTER UNIVERSITY   (Canada)

^b HAMILTON HEALTH SCIENCES   (Canada)

^c Heart and Stroke Found of Ontario ^*

Author keywords

[No Author keywords available]

Indexed keywords

ANTHELMINTIC AGENT; IVERMECTIN;

ANIMAL; ANIMAL DISEASE; ARTICLE; ASCARIDOIDEA; ENTEROBIASIS; FEMALE; ISOLATION AND PURIFICATION; MALE; MOUSE; MOUSE STRAIN; ORAL DRUG ADMINISTRATION; PARASITOLOGY; RAT; RAT STRAIN; RODENT DISEASE; TREATMENT OUTCOME;

ADMINISTRATION, ORAL; ANIMALS; ANTHELMINTICS; FEMALE; IVERMECTIN; MALE; MICE; MICE, INBRED STRAINS; OXYURIASIS; OXYUROIDEA; RATS; RATS, INBRED STRAINS; RODENT DISEASES; TREATMENT OUTCOME;

EID: 0030159925     PISSN: 00236764     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Harkness, J. E., and J. E. Wagner. 1989. Specific diseases and conditions, p. 111-204. In The biology and medicine of rabbits and rodents, 3rd ed. Lea & Febiger, Philadelphia.
2. Lubcke, R., F. A. R. Hutcheson, and D. O. Barbezat. 1992. Impaired intestinal electrolyte transport in rats infested with the common parasite Syphacia muris. Dig. Dis. Sci. 1:60-64.
3. Taffs, L. F. 1976. Pinworm infection in laboratory rodents: a review. Lab. Animals 10:1-13.
4. Jacobson, R. H., and N. D. Reed. 1974. The thymus dependency of resistance to pinworm infection in mice. J. Parasitol. 60:976-979.
5. Chang, K. F. 1952. Life cycle studies on the nematode Syphacia obvelata. Am. J. Hyg. 56:14-21.
6. Taylor, D. M. 1992. Eradication of pinworms (Syphacia obvelata) from Syrian hamsters in quarantine. Lab. Anim. Sci. 42:413-414.
7. Tetzlaff, R. D., and W. D. Weir. 1978. Anthelmintic control of concurrent Hymenolepis nana and Syphacia obvelata infections in the mouse with uredofos. Lab. Anim. Sci. 28:287-289.
8. McArthur, J. A., and M. Wood. 1978. Control of oxyurid in mice using thiabendazole. Lab. Anim. Sci. 12:141-143.
9. Sharp, J. W., and R. B. Wescot. 1976. Anthelmintic efficacy of mebendazole for pinworm infection in mice. Lab. Anim. Sci. 26:222-223.
10. Flynn, B. M., P. A. Brown, J. M. Eckstein, et al. 1989. Treatment of Syphacia obvelata in mice using ivermectin. Lab. Anim. Sci. 39:461-463.
11. Ostlind, D. A., M. A. Nartowicz, and W. G. Mickle. 1985. Efficacy of ivermectin against Syphacia obvelata (nematode) in mice. J. Helminthol. 59:257-261.
12. Owen, D., and J. A. Turton. 1979. Eradication of the pinworm Syphacia obvelata from an animal unit by anthelmintic therapy. Lab. Animals 13:115-118,
13. Baumans, V., R. Havenaar, and H. Van Herck. 1988. The use of repeated treatment with ivomec and neguvon spray in the control of murine fur mites and oxyurid worms. Lab. Animals 22:246-249.
14. Battles, A. H., S. W. Adams, C. H. Courtney, et al. 1987. Efficacy of ivermectin against natural infection of Syphacia muris in rats. Lab. Anim. Sci. 37:791-792.
15. Lipman, N. S., S. D. Dalton, A. R. Stewart, et al. 1994. Eradication of pinworms (Syphacia obvelata) from a large mouse breeding colony by combination oral anthelmintic therapy. Lab. Anim Sci. 44:517-520.
16. Huerkamp, M. J. 1993. Ivermectin eradication of pinworms from rats kept in ventilated cages. Lab. Anim. Sci. 43:86-90.
17. Campbell, W. C., M. H. Fisher, E. O. Stapley, et al. 1983. Ivermectin. a potent new antiparasitic agent. Science 221:823-828.
18. Bennett, D. G. 1986. Clinical pharmacology of ivermectin. J. Am. Vet. Med. Assoc. 189:100-104.
19. Lankas, G. R., and L. R. Gordon. 1989. Acute toxicity of ivermectin, p. 89-112. In W. C. Campbell (ed.), Ivermectin and abamactin. Springer-Verlag. New York.
20. Levee, E. L., M. M. Klinger, C. C. Kaiser, et al. 1994. A practical delivery method for oral administration of ivermectin to large colonies of rodents. Contemp Topics Lab. Anim. Sci. 33:68-70.
21. Kerrick, G. P., D. E. Hoskins, and D. H. Ringler. 1995. Eradication of pinworms from rats by using ivermectin in the drinking water. Contemp. Topics Lab. Anim. Sci. 34:78-79.
22. Diggs, H. E., D. J. Feller, J. C. Crabbe, et al. 1990. Effect of chronic ivermectin treatment in GABA receptor function in ethanol withdrawal-seizure prone and resistant mice. Lab. Anim. Sci. 40:68-71.
23. Poul, J. M. 1988. Effects of perinatal ivermectin exposure on behavioral development of rats. Neurotoxicol. Teratol. 10:267-272.
24. Lankas, G. R., D. H. Minsker, and R. T. Robertson. 1989. Effect of ivermectin on reproduction and neonatal toxicity in rats. Fed. Chem. Toxicol. 27:523-529.