Insight: Demographic differences and associations with one-year outcome in schizophrenia and schizoaffective disorder

Clinical Schizophrenia and Related Psychoses

Volumn 4, Issue 3, 2010, Pages 169-175

  Wiffen, Benjamin D R ^a   Rabinowitz, Jonathan ^b   Fleischhacker, W Wolfgang ^c   David, Anthony S ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b BAR ILAN UNIVERSITY   (Israel)

^c INNSBRUCK MEDICAL UNIVERSITY   (Austria)

Author keywords

Awareness; Clinical trial; Compliance; Demographic; Insight; Outcome

Indexed keywords

LONG ACTING DRUG; RISPERIDONE;

ADULT; AGED; ARTICLE; AWARENESS; CLINICAL TRIAL; DEMOGRAPHY; FEMALE; HUMAN; INTROSPECTION; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; OPEN STUDY; OUTCOME ASSESSMENT; PATIENT ASSESSMENT; PATIENT COMPLIANCE; POSITIVE AND NEGATIVE SYNDROME SCALE; PSYCHIATRIC DIAGNOSIS; SCHIZOAFFECTIVE PSYCHOSIS; SCHIZOPHRENIA;

ADOLESCENT; ADULT; AGE DISTRIBUTION; AGED; AGED, 80 AND OVER; ANALYSIS OF VARIANCE; ANTIPSYCHOTIC AGENTS; ATTITUDE TO HEALTH; AWARENESS; COHORT STUDIES; FEMALE; HUMANS; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; PATIENT COMPLIANCE; PSYCHIATRIC STATUS RATING SCALES; PSYCHOTIC DISORDERS; RISPERIDONE; SCHIZOPHRENIA; SCHIZOPHRENIC PSYCHOLOGY; SEX DISTRIBUTION; SOCIOECONOMIC FACTORS; TREATMENT OUTCOME; YOUNG ADULT;

EID: 77957659731     PISSN: 19351232     EISSN: None     Source Type: Journal    
DOI: 10.3371/CSRP.4.3.3     Document Type: Article

References (49)

1. Amador XF, David AS, editors. Insight and psychosis: awareness of illness in schizophrenia and related disorders. 2nd ed. New York: Oxford University Press; 2004.
2. David AS. Insight and psychosis. Br J Psychiatry 1990;156(6):798-808.
3. Amador XF, Gorman JM. Psychopathologic domains and insight in schizophrenia. Psychiatr Clin North Am 1998;21(1):27-42.
4. Keshavan MS, Rabinowitz J, DeSmedt G, Harvey PD, Schooler N. Correlates of insight in first episode psychosis. Schizophr Res 2004;70(2-3):187-194. (Pubitemid 39141097)
5. Weiler MA, Fleisher MH, McArthur-Campbell D. Insight and symptom change in schizophrenia and other disorders. Schizophr Res 2000;45(1-2):29-36.
6. Carpenter WT Jr, Strauss JS, Bartko JJ. Flexible system for the diagnosis of schizophrenia: Report from the WHO International Pilot Study of Schizophrenia. Science 1973;182(4118):1275-1278.
7. Kemp R, David AS. Insight and compliance. In: Blackwell B, editor. Treatment compliance and the therapeutic alliance. Amsterdam: Harwood Academic Publishers; 1997. p. 61-86.
8. Sapara A, Cooke M, Fannon D, Francis A, Buchanan RW, Anilkumar AP, et al. Prefrontal cortex and insight in schizophrenia: a volumetric MRI study. Schizophr Res 2007;89(1-3):22-34. (Pubitemid 44881313)
9. Larøi F, Fannemel M, Rønneberg U, Flekkøy K, Opjordsmoen S, Dullerud R, et al. Unawareness of illness in chronic schizophrenia and its relationship to structural brain measures and neuropsychological tests. Psychiatry Res 2000;100(1):49-58.
10. Amador XF, Strauss DH, Yale SA, Gorman JM. Awareness of illness in schizophrenia. Schizophr Bull 1991;17(1):113-132.
11. Aleman A, Agrawal N, Morgan KD, David AS. Insight in psychosis and neuropsychological function: meta-analysis. Br J Psychiatry 2006;189(3):204-212. (Pubitemid 44343464)
12. David A, Buchanan A, Reed A, Almeida O. The assessment of insight in psychosis. Br J Psychiatry 1992;161(5):599-602.
13. Moore O, Cassidy E, Carr A, O'Callaghan E. Unawareness of illness and its relationship with depression and self-deception in schizophrenia. Eur Psychiatry 1999;14(5):264-269. (Pubitemid 36187785)
14. Mintz AR, Dobson KS, Romney DM. Insight in schizophrenia: a meta-analysis. Schizophr Res 2003;61(1):75-88.
15. McEvoy JP, Johnson J, Perkins D, Lieberman JA, Hamer RM, Keefe RS, et al. Insight in first-episode psychosis. Psychol Med 2006;36(10):1385-1393.
16. Mohamed S, Rosenheck R, McEvoy J, Swartz M, Stroup S, Lieberman JA. Cross-sectional and longitudinal relationships between insight and attitudes toward medication and clinical outcomes in chronic schizophrenia. Schizophr Bull 2009;35(2):336-346.
17. Rossell S, Coakes J, Shapleske J, Woodruff P, David A. Insight: its relationship with cognitive function, brain volume and symptoms in schizophrenia. Psychol Med 2003;33(1):111-119. (Pubitemid 36113406)
18. David A, van Os J, Jones P, Harvey I, Foerster A, Fahy T. Insight and psychotic illness. Cross-sectional and longitudinal associations. Br J Psychiatry 1995;167(5):621-628. (Pubitemid 26197772)
19. Amador XF, Strauss DH, Yale SA, Flaum MM, Endicott J, Gorman JM. Assessment of insight in psychosis. Am J Psychiatry 1993;150(6):873-879.
20. Fennig S, Everett E, Bromet EJ, Jandorf L, Fennig SR, Tanenberg-Karant M, et al. Insight in first-admission psychotic patients. Schizophr Res 1996;22(3):257-263.
21. Amador XF, Flaum M, Andreasen NC, Strauss DH, Yale SA, Clark SC, et al. Awareness of illness in schizophrenia and schizoaffective and mood disorders. Arch Gen Psychiatry 1994;51(10):826-836. (Pubitemid 24313308)
22. Mintz AR, Addington J, Addington D. Insight in early psychosis: a 1-year follow-up. Schizophr Res 2004;67(2-3):213-217. (Pubitemid 38251451)
23. Saeedi H, Addington J, Addington D. The association of insight with psychotic symptoms, depression, and cognition in early psychosis: a 3-year follow-up. Schizophr Res 2007;89(1-3):123-128. (Pubitemid 44881312)
24. David AS. The clinical importance of insight: an overview. In: Amador XF, David AS, editors. Insight and psychosis: awareness of illness in schizophrenia and related disorders. 2nd ed. Oxford: Oxford University Press; 2004.
25. Drake RJ, Dunn G, Tarrier N, Bentall RP, Haddock G, Lewis SW. Insight as a predictor of the outcome of first-episode nonaffective psychosis in a prospective cohort study in England. J Clin Psychiatry 2007;68(1):81-86. (Pubitemid 46220128)
26. Rosen K, Garety P. Predicting recovery from schizophrenia: a retrospective comparison of characteristics at onset of people with single and multiple episodes. Schizophr Bull 2005;31(3):735-750. (Pubitemid 41253322)
27. Yen CF, Yeh ML, Chen CS, Chung HH. Predictive value of insight for suicide, violence, hospitalization, and social adjustment for outpatients with schizophrenia: A prospective study. Compr Psychiatry 2002;43(6):443-447.
28. Kemp R, Hayward P, Applewhaite G, Everitt B, David A. Compliance therapy in psychotic patients: randomised controlled trial. BMJ 1996;312(7027):345-349. (Pubitemid 26050038)
29. McEvoy JP, Apperson LJ, Appelbaum PS, Ortlip P, Brecosky J, Hammill K, et al. Insight in schizophrenia. Its relationship to acute psychopathology. J Nerv Ment Dis 1989;177(1):43-47. (Pubitemid 19043858)
30. Mohamed S, Rosenheck R, McEvoy J, Swartz M, Stroup S, Lieberman JA. Cross-sectional and longitudinal relationships between insight and attitudes toward medication and clinical outcomes in chronic schizophrenia. Schizophr Bull 2008:35(2):336-346.
31. Smith TE, Hull JW, Goodman M, Hedayat-Harris A, Willson DF, Israel LM, et al. The relative influences of symptoms, insight, and neurocognition on social adjustment in schizophrenia and schizoaffective disorder. J Nerv Ment Dis 1999;187(2):102-108. (Pubitemid 29091766)
32. Watson PW, Garety PA, Weinman J, Dunn G, Bebbington PE, Fowler D, et al. Emotional dysfunction in schizophrenia spectrum psychosis: the role of illness perceptions. Psychol Med 2006;36(6):761-770. (Pubitemid 43744769)
33. Tait L, Birchwood M, Trower P. Predicting engagement with services for psychosis: Insight, symptoms and recovery style. Br J Psychiatry 2003;182(2):123-128. (Pubitemid 36177234)
34. Yen CF, Chen CS, Ko CH, Yeh ML, Yang SJ, Yen JY, et al. Relationships between insight and medication adherence in outpatients with schizophrenia and bipolar disorder: prospective study. Psychiatry Clin Neurosci 2005;59(4):403-409.
35. Lincoln TM, Lullmann E, Rief W. Correlates and long-term consequences of poor insight in patients with schizophrenia. A systematic review. Schizophr Bull 2007;33(6):1324-1342. (Pubitemid 350022767)
36. Fleischhacker WW, Eerdekens M, Karcher K, Remington G, Llorca PM, Chrzanowski W, et al. Treatment of schizophrenia with long-acting injectable risperidone: a 12-month open-label trial of the first long-acting second-generation antipsychotic. J Clin Psychiatry 2003;64(10):1250-1257.
37. Eerdekens M, Rasmussen M, Vermeulen A, et al., editors. Kinetics and safety of a novel risperidone depot. Proceedings of the American Psychiatric Association, 2000 Annual Meeting; 2000 May 13-18 2000; Chicago, Illinois.
38. Kay SR, Fiszbein A, Opler LA. The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophr Bull 1987;13(2):261-276. (Pubitemid 18039085)
39. Kay SR, Singh MM. The positive-negative distinction in drug-free schizophrenic patients: stability, response to neuroleptics, and prognostic significance. Arch Gen Psychiatry 1989;46:711-718.
40. Sanz M, Constable G, Lopez-Ibor I, Kemp R, David A. A comparative study of insight scales and their relationship to psychopathological and clinical variables. Psychol Med 1998;28(2):437-446. (Pubitemid 28197558)
41. Lysaker PH, Bell MD, Bryson G, Kaplan E. Personality as a predictor of the variability of insight in schizophrenia. J Nerv Ment Dis 1999;187(2):119-122. (Pubitemid 29091771)
42. Thompson KN, McGorry PD, Harrigan SM. Reduced awareness of illness in first-episode psychosis. Compr Psychiatry 2001;42(6):498-503.
43. Cuesta MJ, Peralta V. Lack of insight in schizophrenia. Schizophr Bull 1994;20(2):359-366.
44. Ghaemi SN, Rosenquist KJ. Insight in mood disorders: an empirical and conceptual review. In: Amador XF, David AS, editors. Insight and psychosis: awareness of illness in schizophrenia and related disorders. 2nd ed. Oxford: Oxford University Press; 2004.
45. Alloy LB, Abramson LY. Judgment of contingency in depressed and nondepressed students: sadder but wiser? J Exp Psychol Gen 1979;108(4):441-485.
46. Garety PA, Kuipers L, Fowler D, Chamberlain F, Dunn G. Cognitive behavioural therapy for drug-resistant psychosis. Br J Med Psychol 1994;67:259-271. (Pubitemid 24292315)
47. Rathod S, Kingdon D, Smith P, Turkington D. Insight into schizophrenia: the effects of cognitive behavioural therapy on the components of insight and association with sociodemographics - data on a previously published randomised controlled trial. Schizophr Res 2005;74(2-3):211-219. (Pubitemid 40255079)
48. Moritz S, Woodward TS. Metacognitive training in schizophrenia: from basic research to knowledge translation and intervention. Curr Opin Psychiatry 2007;20(6):619-625.
49. Kemp R, Kirov G, Everitt B, Hayward P, David A. Randomised controlled trial of compliance therapy. 18-month follow-up. Br J Psychiatry 1998;172(5):413-419. (Pubitemid 28204550)