Oral antibiotics for perforated appendicitis is not recommended

Danish Medical Bulletin

Volumn 57, Issue 9, 2010, Pages

  Alamili, Mahdi ^a   Gögenur, Ismail ^a   Rosenberg, Jacob ^a  

^a GENTOFTE UNIVERSITY HOSPITAL   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN PLUS CLAVULANIC ACID; AMPICILLIN; ANTIBIOTIC AGENT; CEFTIZOXIME; CHLORAMPHENICOL; CLINDAMYCIN; COTRIMOXAZOLE; GENTAMICIN; LEVOFLOXACIN; METRONIDAZOLE; PENICILLIN G; PLACEBO; SULBACTAM; ANTIINFECTIVE AGENT;

ABDOMINAL ABSCESS; ABDOMINAL DISTENSION; ABDOMINAL PAIN; ABDOMINAL TENDERNESS; APPENDIX PERFORATION; CATHETER INFECTION; CLOSTRIDIUM DIFFICILE INFECTION; COCHRANE LIBRARY; DEHYDRATION; DRUG COST; EMBASE; FEVER; HEALTH CARE COST; HUMAN; LAPAROTOMY; LEUKOCYTE COUNT; MEDLINE; PERCUTANEOUS DRAINAGE; PHLEGMON; POSTOPERATIVE PERIOD; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; SMALL INTESTINE OBSTRUCTION; SYSTEMATIC REVIEW; WOUND INFECTION; ANTIBIOTIC PROPHYLAXIS; APPENDECTOMY; APPENDICITIS; ECONOMICS; INTRAVENOUS DRUG ADMINISTRATION; ORAL DRUG ADMINISTRATION;

ADMINISTRATION, ORAL; ANTI-BACTERIAL AGENTS; ANTIBIOTIC PROPHYLAXIS; APPENDECTOMY; APPENDICITIS; HUMANS; INFUSIONS, INTRAVENOUS;

EID: 77957652496     PISSN: 16039629     EISSN: 16039629     Source Type: Journal    
DOI: None     Document Type: Review

References (18)

1. http://www.sst.dk/informatik_og_sundhedsdata/download_sundhedsstatistik/planmateriale/lps/dsns.aspx (20 September 2009).
2. Cohn SM, Lipsett PA, Buchman TG et al. Comparison of intravenous/oral ciprofloxacin plus metronidazol versus piperacillin/tazobactam in the treatment of complicated intraabdominal infections. Ann Surg 1999;232:254-62.
3. Solomkin JS, Reinhart HH, Dellinger EP et al. Results of a randomized trial comparing sequential intravenous/oral treatment with ciprofloxacin plus metronidazol to imipenem/cilastatin for intra-abdominal infections. Ann Surg 1996;223:303-15.
4. Starakis I, Karravias D, Asimakopoulos C et al. Results of a prospective, randomized, double blind comparison of the efficacy and the safety of sequential ciprofloxacin (intravenous/oral) + metronidazol (intravenous/ oral) with ceftriaxone (intravenous) + metronidazol (intravenous/oral) for the treatment of intra-abdominal infections. Intl J Antimicrob Agents 2003;21:49-57.
5. Walters DJ, Solomkin JS, Paladino JA. Cost effectiveness of ciprofloxacin plus metronidazol versus imipenem-cilastatin in the treatment of intraabdominal infections. Pharmacoeconomics 1999;5:551-61.
6. Wacha H, Warren B, Bassaris H et al. Comparison of sequential intravenous ciprofloxacin plus metronidazol with intravenous ceftriaxone plus metronidazol for the treatment of complicated intra-abdominal infections. Surg Infect 2006;7:341-54.
7. Peacock JE, Pegram PS, Weber SF et al. Prospective, randomized comparison of sequential intravenous followed by oral ciprofloxacin with intravenous ceftazidime in the treatment of serious infections. Am J Med 1989;87:185-90.
8. Banani SA, Talei A. Can oral metronidazol substitute parental drug therapy in acute appendicitis? A new policy in the management of simple or complicated appendicitis with localized peritonitis: a randomized controlled clinical trial. Am Surg 1999;65:411-6.
9. Adibe OO, Barnaby K, Dobies J et al. Postoperative antibiotic therapy for children with perforated appendicitis: long course of intravenous antibiotics versus early conversion to an oral regimen. Am J Surg 2008;195:141-3.
10. Rice HE, Brown RL, Gollin G et al. Results of a pilot trial comparing prolonged intravenous antibiotics with sequential intravenous/oral antibiotics for children with perforated appendicitis. Arch Surg 2001;136:1391-5.
11. Taylor E, Berjis A, Bosch T et al. The efficacy of postoperative oral antibiotics in appendicitis: a randomized prospective double blinded study. Am Surg 2004;70:858-62.
12. Gollin G, Abarbanell A, Moores D. Oral antibiotics in the management of perforated appendicitis in children. Am Surg 2002;68:1072-4.
13. Andersen BR, Kallehave FL, Andersen HK. Antibiotics versus placebo for prevention of postoperative infection after appendicectomy. Cochrane Database Syst Rev 2005;(3):CD001439
14. Schwartz MZ, Tapper D, Solenberger RI. Management of perforated appendicitis in children. Ann Surg 1983;197:407-11.
15. Lund DP, Murphy EU. Management of perforated appendicitis in children: a decade of aggressive treatment. J Pediatr Surg 1994;29:1130-4.
16. Strovoff MC, Totten M, Glick PL. PIC lines save money and hasten discharge in the care of children with ruptured appendicitis. J Pediatr Surg 1994;29:245-7.
17. Hoelzer DJ, Zabel DD, Zern JT. Determinning duration of antibiotic use in children with complicated appendicitis. Pediatr Infect Dis J 1999;18:979-82.
18. Lelli JL Jr., Drongowski RA, Raviz S et al. Historical changes in the postoperative treatment of appendicitis in children: impact on medical outcome. J Pediatr Surg 2000;35:239-45.