Postoperative antibiotic therapy for children with perforated appendicitis: long course of intravenous antibiotics versus early conversion to an oral regimen

American Journal of Surgery

Volumn 195, Issue 2, 2008, Pages 141-143

  Adibe, Obinna O ^a   Barnaby, Karen ^a   Dobies, Jennifer ^a   Comerford, Monica ^a   Drill, Antoinette ^a   Walker, Natalie ^a   Mattei, Peter ^a  

^a CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

Author keywords

Intravenous antibiotics; Oral antibiotics; Perforated appendicitis; Postoperative antibiotic therapy

Indexed keywords

ANTIBIOTIC AGENT; COTRIMOXAZOLE; GENTAMICIN; METRONIDAZOLE; SULTAMICILLIN;

ABDOMINAL ABSCESS; ADOLESCENT; ADULT; ANTIBIOTIC THERAPY; APPENDECTOMY; APPENDIX PERFORATION; ARTICLE; CHILD; CONTROLLED STUDY; COST EFFECTIVENESS ANALYSIS; DRUG EFFICACY; FEMALE; HOSPITAL PATIENT; HOSPITAL READMISSION; HUMAN; HUMAN TISSUE; INFANT; LONG TERM CARE; MAJOR CLINICAL STUDY; MALE; MONOTHERAPY; OUTPATIENT; POSTOPERATIVE CARE; PREOPERATIVE TREATMENT; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SHORT COURSE THERAPY;

ADMINISTRATION, ORAL; ANTI-BACTERIAL AGENTS; APPENDECTOMY; APPENDICITIS; CHILD; CHILD, PRESCHOOL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; DRUG THERAPY, COMBINATION; FEMALE; FOLLOW-UP STUDIES; HUMANS; INFANT; INFUSIONS, INTRAVENOUS; LENGTH OF STAY; MALE; POSTOPERATIVE CARE; PROBABILITY; RETROSPECTIVE STUDIES; RISK ASSESSMENT; TREATMENT OUTCOME;

EID: 38049025119     PISSN: 00029610     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.amjsurg.2007.10.002     Document Type: Article

References (13)

1. Muehlstedt S.G., Pham T.Q., and Schmeling D.J. The management of pediatric appendicitis: a survey of North American pediatric surgeons. J Pediatr Surg 39 (2004) 875-879
2. Chen C., Botelho C., Cooper A., et al. Current practice patterns in the treatment of perforated appendicitis in children. J Am Coll Surg 196 (2003) 212-221
3. Rice H.E., Brown R.L., Gollin G., et al. Results of a pilot trial comparing prolonged intravenous antibiotics with sequential intravenous/oral antibiotics for children with perforated appendicitis. Arch Surg 136 (2001) 1391-1395
4. Schwartz M.Z., Tapper D., and Solenberger R.I. Management of perforated appendicitis in children. Ann Surg 197 (1983) 407-411
5. Lund D.P., and Murphy E.U. Management of perforated appendicitis in children: a decade of aggressive treatment. J Pediatr Surg 29 (1994) 1130-1134
6. Strovoff M.C., Totten M., and Glick P.L. PIC lines save money and hasten discharge in the care of children with ruptured appendicitis. J Pediatr Surg 29 (1994) 245-247
7. Fishman S.J., Pelosi L., Klavon S.L., et al. Perforated appendicitis: prospective outcome analysis for 150 children. J Pediatr Surg 35 (2000) 923-926
8. Banani S.A., and Talei A. Can oral metronidazole substitute parenteral drug therapy in acute appendicitis?. A new policy in the management of simple or complicated appendicitis with local peritonitis: a randomized controlled clinical trial. Am Surg 65 (1999) 411-416
9. Styrud J., Eriksson S., and Granstrom L. Treatment of perforated appendicitis: an analysis of 362 patients during 8 years. Dig Surg 15 (1998) 683-686
10. Solomkin J.S., Reinhart H.H., Dellinger E.P., et al. Results of a randomized trial comparing sequential intravenous/oral treatment with ciprofloxacin plus metronidazole to imipenem/cilastatin for intra-abdominal infections. Ann Surg 223 (1996) 303-315
11. Gollin G., Abarbanell A., and Moores D. Oral antibiotics in the management of perforated appendicitis in children. Am Surg 68 (2002) 1072-1074
12. Cunha B.A. Intravenous to oral antibiotic switch therapy. Drugs Today 37 (2001) 311-319
13. Branton L.L., Lazo J.S., and Parker K.L. Goodman and Gilman's The Pharmacological Basis of Therapeutics (2006), McGraw-Hill, New York, NY