CD90/THY1 is overexpressed in prostate cancer-associated fibroblasts and could serve as a cancer biomarker

Modern Pathology

Volumn 23, Issue 10, 2010, Pages 1346-1356

  True, Lawrence D ^a,g   Zhang, Hui ^b,g   Ye, Mingliang ^b,h   Huang, Chung Ying ^a   Nelson, Peter S ^c   Von Haller, Priska D ^a,d   Tjoelker, Larry W ^d,i   Kim, Jong Seo ^e   Qian, Wei Jun ^e   Smith, Richard D ^e   Ellis, William J ^f   Liebeskind, Emily S ^a,f   Liu, Alvin Y ^a,f  

^a UNIVERSITY OF WASHINGTON   (United States)

^b INSTITUTE FOR SYSTEMS BIOLOGY   (United States)

^c USA   (United States)

^d Analytical Sciences   (United States)

^e PACIFIC NORTHWEST NATIONAL LABORATORY   (United States)

^f UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^g JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^h DALIAN INSTITUTE OF CHEMICAL PHYSICS   (China)

ⁱ XORI   (United States)

Author keywords

Cancer; CD90 variant; Glycoproteins; Prostate; Proteomics; Stroma; Urine analysis

Indexed keywords

BIOLOGICAL MARKER; MESSENGER RNA; THY 1 ANTIGEN;

ANTIGEN EXPRESSION; ARTICLE; CARCINOGENESIS; CELLULAR DISTRIBUTION; FIBROBLAST; GENE EXPRESSION; GLEASON SCORE; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MALE; PRIORITY JOURNAL; PROSTATE CANCER; PROSTATECTOMY; PROTEOMICS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR GROWTH; URINALYSIS;

EID: 77957590276     PISSN: 08933952     EISSN: 15300285     Source Type: Journal    
DOI: 10.1038/modpathol.2010.122     Document Type: Article

References (31)

1. Cunha GR, Ricke W, Thomson A, et al. Hormonal, cellular, and molecular regulation of normal and neoplastic prostatic development. J Steroid Biochem Mol Biol 2004;92:221-236.
2. Sung SY, Chung LW. Prostate tumor-stroma interaction: molecular mechanisms and opportunities for therapeutic targeting. Differentiation 2002;70: 506-521.
3. Liu AY, True LD. Characterization of prostate cell types by CD cell surface molecules. Am J Pathol 2002;160: 37-43.
4. Liu AY, Roudier MP, True LD. Heterogeneity in primary and metastatic prostate cancer as defined by cell surface CD profile. Am J Pathol 2004;165: 1543-1556.
5. Zhang H, Li XJ, Martin DB, et al. Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry. Nat Biotechnol 2003;21:660-666.
6. Liu AY, Zhang H, Sorensen CM, et al. Analysis of prostate cancer by proteomics using tissue specimens. J Urol 2005;173:73-78.
7. Tian Y, Zhou Y, Elliott S, et al. Solid-phase extraction of N-linked glycopeptides. Nat Protocols 2007;2: 334-339.
8. Zhang H, Liu AY, Loriaux P, et al. Mass spectrometric detection of tissue proteins in plasma. Mol Cell Proteomics 2007;6:64-67.
9. Eng J, McCormack AL, Yates JR. An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database. J Am Mass Spectrom 1994;5:976-989.
10. Keller A, Nesvizhskii AI, Kolker E, et al. Empirical statistical model to estimate the accuracy of peptide identification made by MS/MS and database search. Anal Chem 2003;74:5383-5392.
11. Bause E. Structural requirements of N-glycosylation of proteins. Studies with proline peptides as conformational probes. Biochem J 1983;209:331-336.
12. Liu AY, True LD, LaTray L, et al. Cell-cell interaction in prostate gene regulation and cytodifferentiation. Proc Natl Acad Sci 1997;94:10705-10710.
13. Emmert-Buck MR, Bonner RF, Smith PD, et al. Laser capture microdissection. Science 1996;274: 998-1001.
14. von Haller PD, Yi E, Donohoe S, et al. The application of new software tools to quantitative protein profiling via isotope-coded affinity tag (ICAT) and tandem mass spectrometry: I. Statistically annotated datasets for peptide sequences and proteins identified via the application of ICAT and tandem mass spectrometry to proteins copurifying with T cell lipid rafts. Mol Cell Proteomics 2003;2:426-427.
15. von Haller PD, Yi E, Donohoe S, et al. The application of new software tools to quantitative protein profiling via isotope-coded affinity tag (ICAT) and tandem mass spectrometry: II. Evaluation of tandem mass spectrometry methodologies for large-scale protein analysis, and the application of statistical tools for data analysis and interpretation. Mol Cell Proteomics 2003;2: 428-442.
16. von Haller PD, Donohoe S, Goodlett DR, et al. Mass spectrometric characterization of proteins extracted from Jurkat T cell detergent-resistant membrane domains. Proteomics 2001;1:1010-1021. (Pubitemid 33699617)
17. Pascal LE, Goo Y, Vencio RZN, et al. Gene expression down-regulation in CD90+ prostate tumor-associated stromal cells involves potential organ-specific genes. BMC Cancer 2009;9:317.
18. Pascal LE, Vencio RZN, Page LS, et al. Gene expression relationship between prostate cancer cells of Gleason 3, 4 and normal epithelial cells as revealed by cell type-specific transcriptomes. BMC Cancer 2009;9:452.
19. Koumas L, Smith TJ, Phipps RP. Fibroblast subsets in the human orbit: Thy-1+ and Thy-1- subpopulations exhibit distinct phenotypes. Eur J Immunol 2002;32: 477-485.
20. Koumas L, Smith TJ, Feldon S, et al. Thy-1 expression in human fibroblast subsets defines myofibroblastic or lipofibroblastic phenotypes. Am J Pathol 2003;163: 1291-1300.
21. Zhou Y, Hagood JS, Murphy-Ullrich JE. Thy-1 expression regulates the ability of rat lung fibroblasts to activate transforming growth factor-b in response to fibrogenic stimuli. Am J Pathol 2004;165: 659-669.
22. Fries KM, Sempowski GD, Gaspari AA, et al. CD40 expression by human fibroblasts. Clin Immunol Immunopathol 1995;77:42-51.
23. King AE, Kelly RW, Critchley HO, et al. CD40 expression in uterine tissues: a key regulator of cytokine expression by fibroblasts. J Clin Endocrinol Metab 2001;86:405-412.
24. Hayward SW, Grossfeld GD, Tlsty TD, et al. Genetic and epigenetic influences in prostatic carcinogenesis. Int J Oncol 1998;13:35-47.
25. Zhang Y, Nojima S, Nakayama H, et al. Characteristics of normal stromal components and their correlation with cancer occurrence in human prostate. Oncol Rep 2003;10:207-211.
26. Olapade-Olaopa EO, MacKay EH, Taub NA, et al. Malignant transformation of human prostatic epithelium is associated with the loss of androgen receptor immunoreactivity in the surrounding stroma. Clin Cancer Res 1999;5:569-576.
27. Tuxhorn JA, Ayala GE, Smith MJ, et al. Reactive stroma in human prostate cancer: induction of myofibroblast phenotype and extracellular matrix remodeling. Clin Cancer Res 2002;8:2912-2923.
28. Oudes AJ, Campbell DS, Sorensen CM, et al. Transcriptomes of human prostate cells. BMC Genomics 2006;7:92.
29. Liu AY, LaTray L, van den Engh G. Changes in cell surface molecules associated with in vitro culture of prostatic stromal cells. Prostate 2000;45: 303-312.
30. Saalbach A, Wetzig T, Haustein UF, et al. Detection of human soluble Thy-1 in serum by ELISA. Cell Tissue Res 1999;298:307-315.
31. Seki T, Spurr N, Obata F, et al. The human Thy-1 gene: structure and chromosomal location. Proc Natl Acad Sci 1985;82:6657-6661.