메뉴 건너뛰기




Volumn 83, Issue 4, 2010, Pages 584-596

Alterations in the human blood-epididymis barrier in obstructive azoospermia and the development of novel epididymal cell lines from infertile men

Author keywords

Cellular junctions; Epididymis; Gene regulation; Human cell lines; Infertility; Male reproductive tract; Obstructive azoospermia; Tight junctions

Indexed keywords

CD52 ANTIGEN; CDH2 PROTEIN; CELL PROTEIN; CLAUDIN 1; CLAUDIN 10; CLAUDIN 2; CLAUDIN 3; CLAUDIN 4; CLAUDIN 7; CLAUDIN 8; CRISP1 PROTEIN; CYTOKERATIN; DCXR PROTEIN; DESMOPLAKIN; MEMBRANE PROTEIN; MESSENGER RNA; NPC2 PROTEIN; SODIUM PROTON EXCHANGE PROTEIN 2; SPINLW1 PROTEIN; UNCLASSIFIED DRUG; UVOMORULIN; VIMENTIN;

EID: 77957589986     PISSN: 00063363     EISSN: 15297268     Source Type: Journal    
DOI: 10.1095/biolreprod.110.084459     Document Type: Article
Times cited : (17)

References (55)
  • 1
    • 0025883931 scopus 로고
    • Fecundity and infertility in the United States: Incidence and trends
    • Mosher WD, Pratt WF. Fecundity and infertility in the United States: incidence and trends. Fertil Steril 1991; 56:192-193.
    • (1991) Fertil Steril , vol.56 , pp. 192-193
    • Mosher, W.D.1    Pratt, W.F.2
  • 3
    • 41849137759 scopus 로고    scopus 로고
    • Male infertility
    • Walsh PC, Retik AB, Vaughan ED, Wein AJ (eds.), 8th ed. Philadelphia: Saunders
    • Sigman M, Jarow JP. Male infertility. In: Walsh PC, Retik AB, Vaughan ED, Wein AJ (eds.), Campbell's Urology, 8th ed. Philadelphia: Saunders; 2006:609-653.
    • (2006) Campbell's Urology , pp. 609-653
    • Sigman, M.1    Jarow, J.P.2
  • 4
    • 4444270865 scopus 로고    scopus 로고
    • Causes of azoospermia and their management
    • Schlegel PN. Causes of azoospermia and their management. Reprod Fertil Dev 2004; 16:561-572.
    • (2004) Reprod Fertil Dev , vol.16 , pp. 561-572
    • Schlegel, P.N.1
  • 5
    • 55449119463 scopus 로고    scopus 로고
    • The management of infertility due to obstructive azoospermia
    • Practice Committee of American Society for Reproductive Medicine in Collaboration with Society for Male Reproduction and Urology
    • Practice Committee of American Society for Reproductive Medicine in Collaboration with Society for Male Reproduction and Urology. The management of infertility due to obstructive azoospermia. Fertil Steril 2008; 90:S121-S124.
    • (2008) Fertil Steril , vol.90
  • 6
    • 55449129873 scopus 로고    scopus 로고
    • Evaluation of the azoospermic male
    • Practice Committee of American Society for Reproductive Medicine in Collaboration with Society for Male Reproduction and Urology
    • Practice Committee of American Society for Reproductive Medicine in Collaboration with Society for Male Reproduction and Urology. Evaluation of the azoospermic male. Fertil Steril 2008; 90:S74-S77.
    • (2008) Fertil Steril , vol.90
  • 7
    • 0032324799 scopus 로고    scopus 로고
    • Pathological epididymal obstruction unrelated to vasectomy: Results with microsurgical reconstruction
    • Kim ED, Winkel E, Orejuela F, Lipshultz LI. Pathological epididymal obstruction unrelated to vasectomy: results with microsurgical reconstruction. J Urol 1998; 160:2078-2080. (Pubitemid 128703618)
    • (1998) Journal of Urology , vol.160 , Issue.6 I , pp. 2078-2080
    • Kim, E.D.1
  • 8
    • 0031931447 scopus 로고    scopus 로고
    • Outcome of microsurgical reconstruction in men with suspected epididymal obstruction
    • DOI 10.1016/S0022-5347(01)63745-5
    • Berardinucci D, Zini A, Jarvi K. Outcome of microsurgical reconstruction in men with suspected epididymal obstruction. J Urol 1998; 159:831-834. (Pubitemid 28106537)
    • (1998) Journal of Urology , vol.159 , Issue.3 , pp. 831-834
    • Berardinucci, D.1    Zini, A.2    Jarvi, K.3
  • 9
    • 0031943493 scopus 로고    scopus 로고
    • Surgical sperm retrieval and intracytoplasmic sperm injection as treatment of obstructive azoospermia
    • DOI 10.1093/humrep/13.3.620
    • Dohle GR, Ramos L, Pieters MH, Braat DD, Weber RF. Surgical sperm retrieval and intracytoplasmic sperm injection as treatment of obstructive azoospermia. Hum Reprod 1998; 13:620-623. (Pubitemid 28171957)
    • (1998) Human Reproduction , vol.13 , Issue.3 , pp. 620-623
    • Dohle, G.R.1    Ramos, L.2    Pieters, M.H.E.C.3    Braat, D.D.M.4    Weber, R.F.A.5
  • 11
    • 69649108945 scopus 로고    scopus 로고
    • Intracytoplasmic sperm injection (ICSI)
    • Practice Committee of the American Society for Reproductive Medicine
    • Practice Committee of the American Society for Reproductive Medicine. Intracytoplasmic sperm injection (ICSI). Fertil Steril 2006; 86:S122.
    • (2006) Fertil Steril , vol.86
  • 13
    • 0036131246 scopus 로고    scopus 로고
    • Outcome of in vitro fertilization and intracytoplasmic injection of epididymal and testicular sperm obtained from patients with obstructive and nonobstructive azoospermia
    • Pasqualotto FF, Rossi-Ferragut LM, Rocha CC, Iaconelli A Jr, Borges E Jr. Outcome of in vitro fertilization and intracytoplasmic injection of epididymal and testicular sperm obtained from patients with obstructive and nonobstructive azoospermia. J Urol 2002; 167:1753-1756.
    • (2002) J Urol , vol.167 , pp. 1753-1756
    • Pasqualotto, F.F.1    Rossi-Ferragut, L.M.2    Rocha, C.C.3    Iaconelli Jr., A.4    Borges Jr., E.5
  • 15
    • 38549179293 scopus 로고    scopus 로고
    • Alterations in gene expression in the caput epididymides of nonobstructive azoospermic men
    • DOI 10.1095/biolreprod.107.062760
    • Dubé E, Hermo L, Chan PT, Cyr DG. Alterations in gene expression in the caput epididymides of nonobstructive azoospermic men. Biol Reprod 2008; 78:342-351. (Pubitemid 351159990)
    • (2008) Biology of Reproduction , vol.78 , Issue.2 , pp. 342-351
    • Dube, E.1    Hermo, L.2    Chan, P.T.K.3    Cyr, D.G.4
  • 16
    • 0000972038 scopus 로고
    • Efferent ducts, epididymis, and vas deferens: Structure, functions, and their regulation
    • Knobil E, Neill J (eds.), New York: Raven Press
    • Robaire B, Hermo L. Efferent ducts, epididymis, and vas deferens: structure, functions, and their regulation. In: Knobil E, Neill J (eds.), The Physiology of Reproduction. New York: Raven Press; 1988:999-1080.
    • (1988) The Physiology of Reproduction , pp. 999-1080
    • Robaire, B.1    Hermo, L.2
  • 18
    • 0028914096 scopus 로고
    • Epididymal epithelium: Its contribution to the formation of a luminal fluid microenvironment
    • Hinton BT, Palladino MA. Epididymal epithelium: its contribution to the formation of a luminal fluid microenvironment. Microsc Res Tech 1995; 30:67-81.
    • (1995) Microsc Res Tech , vol.30 , pp. 67-81
    • Hinton, B.T.1    Palladino, M.A.2
  • 19
    • 0037405822 scopus 로고    scopus 로고
    • Contribution of epididymal secretory proteins for spermatozoa maturation
    • DOI 10.1002/jemt.10312
    • Dacheux JL, Gatti JL, Dacheux F. Contribution of epididymal secretory proteins for spermatozoa maturation. Microsc Res Tech 2003; 61:7-17. (Pubitemid 36457542)
    • (2003) Microscopy Research and Technique , vol.61 , Issue.1 , pp. 7-17
    • Dacheux, J.-L.1    Luc Gatti, J.2    Dacheux, F.3
  • 21
    • 26244442091 scopus 로고    scopus 로고
    • Tissue microcircumstances for leukocytic infiltration into the testis and epididymis in mice
    • Itoh M, Terayama H, Naito M, Ogawa Y, Tainosho S. Tissue microcircumstances for leukocytic infiltration into the testis and epididymis in mice. J Reprod Immunol 2005; 67:57-67.
    • (2005) J Reprod Immunol , vol.67 , pp. 57-67
    • Itoh, M.1    Terayama, H.2    Naito, M.3    Ogawa, Y.4    Tainosho, S.5
  • 23
    • 34447258369 scopus 로고    scopus 로고
    • Orchestration of occludins, claudins, catenins and cadherins as players involved in maintenance of the blood-epididymal barrier in animals and humans
    • Cyr DG, Gregory M, Dubé E, Dufresne J, Chan PT, Hermo L. Orchestration of occludins, claudins, catenins and cadherins as players involved in maintenance of the blood-epididymal barrier in animals and humans. Asian J Androl 2007; 9:463-475.
    • (2007) Asian J Androl , vol.9 , pp. 463-475
    • Cyr, D.G.1    Gregory, M.2    Dubé, E.3    Dufresne, J.4    Chan, P.T.5    Hermo, L.6
  • 24
    • 34249671175 scopus 로고    scopus 로고
    • Gene expression profiling and its relevance to the blood-epididymal barrier in the human epididymis
    • Dubé E, Chan PT, Hermo L, Cyr DG. Gene expression profiling and its relevance to the blood-epididymal barrier in the human epididymis. Biol Reprod 2007; 76:1034-1044.
    • (2007) Biol Reprod , vol.76 , pp. 1034-1044
    • Dubé, E.1    Chan, P.T.2    Hermo, L.3    Cyr, D.G.4
  • 25
    • 33645457521 scopus 로고    scopus 로고
    • Identification of multiple claudins in the rat epididymis
    • Gregory M, Cyr DG. Identification of multiple claudins in the rat epididymis. Mol Reprod Dev 2006; 73:580-588.
    • (2006) Mol Reprod Dev , vol.73 , pp. 580-588
    • Gregory, M.1    Cyr, D.G.2
  • 26
    • 0035105853 scopus 로고    scopus 로고
    • Claudin-1 is not restricted to tight junctions in the rat epididymis
    • Gregory M, Dufresne J, Hermo L, Cyr D. Claudin-1 is not restricted to tight junctions in the rat epididymis. Endocrinology 2001; 142:854-863.
    • (2001) Endocrinology , vol.142 , pp. 854-863
    • Gregory, M.1    Dufresne, J.2    Hermo, L.3    Cyr, D.4
  • 27
    • 27744507728 scopus 로고    scopus 로고
    • Segment-specific expression of tight junction proteins, claudin-2 and -10, in the rat epididymal epithelium
    • Guan X, Inai T, Shibata Y. Segment-specific expression of tight junction proteins, claudin-2 and -10, in the rat epididymal epithelium. Arch Histol Cytol 2005; 68:213-225.
    • (2005) Arch Histol Cytol , vol.68 , pp. 213-225
    • Guan, X.1    Inai, T.2    Shibata, Y.3
  • 28
    • 35948991135 scopus 로고    scopus 로고
    • Claudin-7 expressed on lateral membrane of rat epididymal epithelium does not form aberrant tight junction strands
    • Hoboken
    • Inai T, Sengoku A, Hirose E, Iida H, Shibata Y. Claudin-7 expressed on lateral membrane of rat epididymal epithelium does not form aberrant tight junction strands. Anat Rec (Hoboken) 2007; 290:1431-1438.
    • (2007) Anat Rec , vol.290 , pp. 1431-1438
    • Inai, T.1    Sengoku, A.2    Hirose, E.3    Iida, H.4    Shibata, Y.5
  • 29
    • 33645963995 scopus 로고    scopus 로고
    • Claudins and epithelial paracellular transport
    • Van Itallie CM, Anderson JM. Claudins and epithelial paracellular transport. Annu Rev Physiol 2006; 68:403-429.
    • (2006) Annu Rev Physiol , vol.68 , pp. 403-429
    • Van Itallie, C.M.1    Anderson, J.M.2
  • 30
    • 0031440104 scopus 로고    scopus 로고
    • Molecular and functional analysis of cadherin-based adherens junctions
    • Yap AS, Brieher WM, Gumbiner BM. Molecular and functional analysis of cadherin-based adherens junctions. Annu Rev Cell Dev Biol 1997; 13: 119-146.
    • (1997) Annu Rev Cell Dev Biol , vol.13 , pp. 119-146
    • Yap, A.S.1    Brieher, W.M.2    Gumbiner, B.M.3
  • 31
    • 35348841509 scopus 로고    scopus 로고
    • Tight junctions/adherens junctions: Basic structure and function
    • Niessen CM. Tight junctions/adherens junctions: basic structure and function. J Invest Dermatol 2007; 127:2525-2532.
    • (2007) J Invest Dermatol , vol.127 , pp. 2525-2532
    • Niessen, C.M.1
  • 32
    • 0026398910 scopus 로고
    • Developmental regulation of epithelial- and placentalcadherin mRNAs in the rat epididymis
    • Cyr DG, Robaire B. Developmental regulation of epithelial- and placentalcadherin mRNAs in the rat epididymis. Ann N Y Acad Sci 1991; 637: 399-408.
    • (1991) Ann N Y Acad Sci , vol.637 , pp. 399-408
    • Cyr, D.G.1    Robaire, B.2
  • 33
    • 0242468445 scopus 로고    scopus 로고
    • Catenins in the rat epididymis: Their expression and regulation in adulthood and during postnatal development
    • DeBellefeuille S, Hermo L, Gregory M, Dufresne J, Cyr DG. Catenins in the rat epididymis: their expression and regulation in adulthood and during postnatal development. Endocrinology 2003; 144:5040-5049.
    • (2003) Endocrinology , vol.144 , pp. 5040-5049
    • Debellefeuille, S.1    Hermo, L.2    Gregory, M.3    Dufresne, J.4    Cyr, D.G.5
  • 34
    • 26844507118 scopus 로고    scopus 로고
    • Characterization of a novel rat epididymal cell line to study epididymal function
    • Dufresne J, St-Pierre N, Viger RS, Hermo L, Cyr DG. Characterization of a novel rat epididymal cell line to study epididymal function. Endocrinology 2005; 146:4710-4720.
    • (2005) Endocrinology , vol.146 , pp. 4710-4720
    • Dufresne, J.1    St-Pierre, N.2    Viger, R.S.3    Hermo, L.4    Cyr, D.G.5
  • 35
    • 34249737544 scopus 로고    scopus 로고
    • Expression of ion transport-associated proteins in human efferent and epididymal ducts
    • DOI 10.1530/rep.1.00964
    • Kujala M, Hihnala S, Tienari J, Kaunisto K, Hastbacka J, Holmberg C, Kere J, Hoglund P. Expression of ion transport-associated proteins in human efferent and epididymal ducts. Reproduction 2007; 133:775-784. (Pubitemid 46831902)
    • (2007) Reproduction , vol.133 , Issue.4 , pp. 775-784
    • Kujala, M.1    Hihnala, S.2    Tienari, J.3    Kaunisto, K.4    Hastbacka, J.5    Holmberg, C.6    Kere, J.7    Hoglund, P.8
  • 36
    • 0028831069 scopus 로고
    • Cloning, tissue distribution, and functional analysis of the human Na+/N+ exchanger isoform, NHE3
    • Brant SR, Yun CH, Donowitz M, Tse CM. Cloning, tissue distribution, and functional analysis of the human Na+/N+ exchanger isoform, NHE3. Am J Physiol 1995; 269:C198-C206.
    • (1995) Am J Physiol , vol.269
    • Brant, S.R.1    Yun, C.H.2    Donowitz, M.3    Tse, C.M.4
  • 37
    • 77953863028 scopus 로고    scopus 로고
    • Assessing the role of claudins in maintaining the integrity of epididymal tight junctions using novel human epididymal cell lines
    • Dubé E, Dufresne J, Chan PTK, Hermo L, Cyr D. Assessing the role of claudins in maintaining the integrity of epididymal tight junctions using novel human epididymal cell lines. Biol Reprod 2010; 82:1119-1128.
    • (2010) Biol Reprod , vol.82 , pp. 1119-1128
    • Dubé, E.1    Dufresne, J.2    Chan, P.T.K.3    Hermo, L.4    Cyr, D.5
  • 38
    • 0031834686 scopus 로고    scopus 로고
    • The treatment of obstructive azoospermia male infertility - Past, present, and future
    • DOI 10.1016/S0090-4295(98)00089-2, PII S0090429598000892
    • Takihara H. The treatment of obstructive azoospermia in male infertility: past, present, and future. Urology 1998; 51:150-155. (Pubitemid 28267893)
    • (1998) Urology , vol.51 , Issue.5 SUPPL. A , pp. 150-155
    • Takihara, H.1
  • 39
    • 0027504189 scopus 로고
    • Ultrastructural changes in the efferent duct and epididymis of men with obstructive infertility
    • Rajalakshmi M, Kumar BV, Kapur MM, Pal PC. Ultrastructural changes in the efferent duct and epididymis of men with obstructive infertility. Anat Rec 1993; 237:199-207.
    • (1993) Anat Rec , vol.237 , pp. 199-207
    • Rajalakshmi, M.1    Kumar, B.V.2    Kapur, M.M.3    Pal, P.C.4
  • 40
    • 48749121764 scopus 로고    scopus 로고
    • Effects of vasectomy on gene expression profiling along the human epididymis
    • Thimon V, Calvo E, Koukoui O, Legare C, Sullivan R. Effects of vasectomy on gene expression profiling along the human epididymis. Biol Reprod 2008; 79:262-273.
    • (2008) Biol Reprod , vol.79 , pp. 262-273
    • Thimon, V.1    Calvo, E.2    Koukoui, O.3    Legare, C.4    Sullivan, R.5
  • 41
    • 34548175512 scopus 로고    scopus 로고
    • Signaling networks guiding epithelialmesenchymal transitions during embryogenesis and cancer progression
    • Moustakas A, Heldin CH. Signaling networks guiding epithelialmesenchymal transitions during embryogenesis and cancer progression. Cancer Sci 2007; 98:1512-1520.
    • (2007) Cancer Sci , vol.98 , pp. 1512-1520
    • Moustakas, A.1    Heldin, C.H.2
  • 44
    • 0036708432 scopus 로고    scopus 로고
    • Ultrastructural features of the vas deferens from patients undergoing vasectomy and vasectomy reversal
    • Andonian S, Jarvi K, Zini A, Hermo L. Ultrastructural features of the vas deferens from patients undergoing vasectomy and vasectomy reversal. J Androl 2002; 23:691-701.
    • (2002) J Androl , vol.23 , pp. 691-701
    • Andonian, S.1    Jarvi, K.2    Zini, A.3    Hermo, L.4
  • 47
    • 34250863840 scopus 로고    scopus 로고
    • Differential gene expression among the proximal segments of the rat epididymis is lost after efferent duct ligation
    • Turner TT, Johnston DS, Finger JN, Jelinsky SA. Differential gene expression among the proximal segments of the rat epididymis is lost after efferent duct ligation. Biol Reprod 2007; 77:165-171.
    • (2007) Biol Reprod , vol.77 , pp. 165-171
    • Turner, T.T.1    Johnston, D.S.2    Finger, J.N.3    Jelinsky, S.A.4
  • 48
    • 23844528776 scopus 로고    scopus 로고
    • The Snail genes as inducers of cell movement and survival: Implications in development and cancer
    • Barrallo-Gimeno A, Nieto MA. The Snail genes as inducers of cell movement and survival: implications in development and cancer. Development 2005; 132:3151-3161.
    • (2005) Development , vol.132 , pp. 3151-3161
    • Barrallo-Gimeno, A.1    Nieto, M.A.2
  • 49
    • 39849109700 scopus 로고    scopus 로고
    • Crosstalk of tight junction components with signaling pathways
    • Gonzalez-Mariscal L, Tapia R, Chamorro D. Crosstalk of tight junction components with signaling pathways. Biochim Biophys Acta 2008; 1778: 729-756.
    • (2008) Biochim Biophys Acta , vol.1778 , pp. 729-756
    • Gonzalez-Mariscal, L.1    Tapia, R.2    Chamorro, D.3
  • 51
    • 0029941015 scopus 로고    scopus 로고
    • Cases of human infertility are associated with the absence of P34H, an epididymal sperm antigen
    • Boue F, Sullivan R. Cases of human infertility are associated with the absence of P34H, an epididymal sperm antigen. Biol Reprod 1996; 54: 1018-1024. (Pubitemid 126523689)
    • (1996) Biology of Reproduction , vol.54 , Issue.5 , pp. 1018-1024
    • Boue, F.1    Sullivan, R.2
  • 52
    • 0035144826 scopus 로고    scopus 로고
    • Effect of vasectomy on P34H messenger ribonucleic acid expression along the human excurrent duct: A reflection on the function of the human epididymis
    • Legare C, Thabet M, Picard S, Sullivan R. Effect of vasectomy on P34H messenger ribonucleic acid expression along the human excurrent duct: a reflection on the function of the human epididymis. Biol Reprod 2001; 64: 720-727.
    • (2001) Biol Reprod , vol.64 , pp. 720-727
    • Legare, C.1    Thabet, M.2    Picard, S.3    Sullivan, R.4
  • 53
    • 0032908311 scopus 로고    scopus 로고
    • Some vasovasostomized men are characterized by low levels of P34H, an epididymal sperm protein
    • Guillemette C, Thabet M, Dompierre L, Sullivan R. Some vasovasostomized men are characterized by low levels of P34H, an epididymal sperm protein. J Androl 1999; 20:214-219.
    • (1999) J Androl , vol.20 , pp. 214-219
    • Guillemette, C.1    Thabet, M.2    Dompierre, L.3    Sullivan, R.4
  • 54
    • 34548641765 scopus 로고    scopus 로고
    • Structural alterations of epididymal epithelial cells in cathepsin A-deficient mice affect the blood-epididymal barrier and lead to altered sperm motility
    • Hermo L, Korah N, Gregory M, Liu LY, Cyr DG, D'Azzo A, Smith CE. Structural alterations of epididymal epithelial cells in cathepsin A-deficient mice affect the blood-epididymal barrier and lead to altered sperm motility. J Androl 2007; 28:784-797.
    • (2007) J Androl , vol.28 , pp. 784-797
    • Hermo, L.1    Korah, N.2    Gregory, M.3    Liu, L.Y.4    Cyr, D.G.5    D'Azzo, A.6    Smith, C.E.7
  • 55
    • 0036086353 scopus 로고    scopus 로고
    • Changes in gene expression during aging in the Brown Norway rat epididymis
    • Jervis KM, Robaire B. Changes in gene expression during aging in the Brown Norway rat epididymis. Exp Gerontol 2002; 37:897-906.
    • (2002) Exp Gerontol , vol.37 , pp. 897-906
    • Jervis, K.M.1    Robaire, B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.