Pulmonary infection defense after lung transplantation: Does airway ischemia play a role?

Current Opinion in Organ Transplantation

Volumn 15, Issue 5, 2010, Pages 568-571

  Verleden, Geert M ^a   Vos, Robin ^a   Van Raemdonck, Dirk ^a   Vanaudenaerde, Bart ^a  

^a UNIVERSITY HOSPITALS LEUVEN   (Belgium)

Author keywords

bronchial circulation; infection defense; lung transplantation

Indexed keywords

ACUTE GRAFT REJECTION; AIRWAY ISCHEMIA; ASTHMA; BRONCHIOLITIS OBLITERANS; CANCER SURGERY; CHRONIC GRAFT REJECTION; CHRONIC INFLAMMATION; CILIARY MOTILITY; CYSTIC FIBROSIS; HUMAN; ISCHEMIA; LOBECTOMY; LUNG CARCINOMA; LUNG CIRCULATION; LUNG INFECTION; LUNG RESECTION; LUNG TRANSPLANTATION; NONHUMAN; PNEUMONIA; POSTOPERATIVE COMPLICATION; REVASCULARIZATION; REVIEW; RISK ASSESSMENT;

ANASTOMOSIS, SURGICAL; ANIMALS; BRONCHIAL ARTERIES; CILIA; CILIARY MOTILITY DISORDERS; HUMANS; INFLAMMATION MEDIATORS; LUNG; LUNG TRANSPLANTATION; PULMONARY CIRCULATION; REPERFUSION INJURY; RESPIRATORY MUCOSA; RESPIRATORY TRACT INFECTIONS; RISK FACTORS; TREATMENT OUTCOME;

EID: 77957588631     PISSN: 10872418     EISSN: 15317013     Source Type: Journal    
DOI: 10.1097/MOT.0b013e32833debd0     Document Type: Review

References (23)

1. Reitz BA, Wallwork JL, Hunt S.A., et al. Heart-lung transplantation: successful therapy for patients with pulmonary vascular disease. N Engl J Med 1982; 306: 557-564.
2. Patterson GA, Todd TR, Cooper J.D., et al. Airway complications after double lung transplantation. Toronto Lung Transplant Group. J Thorac Cardiovasc Surg 1990; 99: 14-20.
3. Pettersson G, Nørgaard MA, Arendrup H, et al. Direct bronchial artery revascularization and en bloc double lung transplantation: surgical techniques and early outcome. J Heart Lung Transplant 1997; 16: 320-333.
4. Kaiser LR, Pasque MK, Trulock EP, et al. Bilateral sequential lung transplantation: the procedure of choice for double-lung replacement. Ann Thorac Surg 1991; 52: 438-445.
5. Cooper JD, Pearson FG, Patterson G.A., et al. Technique of successful lung transplantation in humans. J Thorac Cardiovasc Surg 1987; 93: 173-181.
6. Gildea TR, Murthy S. Airway healing and complications after lung transplantation. Curr Opin Organ Transplant 2010.
7. Hashimoto M, Tanaka H, Abe S. Quantitative analysis of bronchial wall vascularity in the medium and small airways of patients with asthma and COPD. Chest 2005; 127: 965-972.
8. Li X, Wilson JW Increased vascularity of the bronchial mucosa in mild asthma. Am J Respir Crit Care Med 1997; 156: 229-233.
9. Asai K, Kanazawa H, Otani K., et al. Imbalance between vascular endothelial growth factor and endostatins in induced sputum from asthmatic subjects. J Allergy Clin Immunol 2002; 110: 517-575.
10. McCullagh A, Rosenthal M, Wanner A., et al. The bronchial circulation: worth a closer look - a review of the relationship between the bronchial vasculature and airway inflammation. Pediatr Pulmonol 2010; 45: 1-13.
11. Jackson JR, Seed MP, Kircher C.H., et al. The codependence of angiogenesis and chronic inflammation. FASEB J 1997; 11: 457-465.
12. Deffebach ME, Charan NB, Lakshminarayan S, Butler J. The bronchial circulation. Small, but a vital attribute of the lung. Am Rev Respir Dis 1987; 135: 463-481.
13. Norgaard MA, Andersen CB, Pettersson G. Airway epithelium of transplanted lungs with and without direct bronchial artery revascularization. Eur J Cardiothorac Surg 1999; 15: 37-44.
14. Gade J, Qvortrup K, Andersen C.B., Olsen PS Bronchial transsection and reanastomosis in pigs with and without bronchial arterial circulation. Ann Thorac Surg 2001; 71: 332-336.
15. Kelly WF, Sanghani S, Barnett S.D., et al. Significance of early bronchoscopic airway abnormalities after lung transplantation. J Heart Lung Transplant 2003; 22: 583-586.
16. Christie JD, Edwards LB, Aurora P, et al. The Registry of the International Society for Heart and Lung Transplantation: Twenty-sixth Official Adult Lung and Heart-Lung Transplantation Report-2009. J Heart Lung Transplant 2009; 28: 1031-1049.
17. Wagner EM, Foster WM The role of the bronchial circulation in soluble particle clearance. Environ Health Perspect 2001; 109: 563-565.
18. Ross DJ, Cole AM, Yoshioka D, et al. Increased bronchoalveolar lavage human β-defensin type-2 in bronchiolitis obliterans syndrome after lung transplantation. Transplantation 2004; 78: 1222-1224.
19. Anderson RL, Hiemstra PS, Ward C, et al. Antimicrobial peptides in lung transplant recipients with bronchiolitis obliterans syndrome. Eur Respir J 2008; 32: 670-677.
20. Rea F, Marulli G, Loy M., et al. Salvage right pneumonectomy in a patient with bronchial-pulmonary artery fistula after bilateral sequential lung transplantation. J Heart Lung Transplant 2006; 25: 1383-1386.
21. Lowry CM, Marty FM, Vargas S.O., et al. Safety of aerosolized liposomal versus deoxycholate amphotericin B formulations for prevention of invasive fungal infections following lung transplantation: a retrospective study. Transpl Infect Dis 2007; 9: 121-125.
22. Schulze-Neick I., Ho Y, Bush A., et al. Severe airflow limitation after the unifocalization procedure: clinical and morphological correlates. Circulation 2000; 102 (SUPPL. 3): III142-III147.
23. Melloul E, Egger B, Krueger T., et al. Mortality, complications and loss of pulmonary function after pneumonectomy vs. sleeve lobectomy in patients younger and older than 70 years. Interact Cardiovasc Thorac Surg 2008; 7: 986-989.