Translational research in corneal epithelial wound healing

Eye and Contact Lens

Volumn 36, Issue 5, 2010, Pages 300-304

  Nishida, Teruo ^a  

^a YAMAGUCHI UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Fibronectin; Insulin like growth factor 1; Neurotrophic keratopathy; Persistent corneal epithelial defects; Substance P; Wound healing

Indexed keywords

EYE DROPS; FIBRONECTIN; SOMATOMEDIN C; SUBSTANCE P;

BASEMENT MEMBRANE; CELL MIGRATION; CORNEA EPITHELIUM; CORNEA INJURY; HUMAN; KERATOPATHY; NERVE STIMULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVIEW; WOUND HEALING;

ANIMALS; DRUG SYNERGISM; EPITHELIUM, CORNEAL; FIBRONECTINS; HUMANS; INSULIN-LIKE GROWTH FACTOR I; NEUROTRANSMITTER AGENTS; OLIGOPEPTIDES; OPHTHALMIC SOLUTIONS; SUBSTANCE P; TRANSLATIONAL RESEARCH; WOUND HEALING;

EID: 77957585329     PISSN: 15422321     EISSN: None     Source Type: Journal    
DOI: 10.1097/ICL.0b013e3181f016d0     Document Type: Review

References (65)

1. Cowen SJ, Anhalt GJ, Wicha M.S., et al. Distribution of pemphigus and pemphigoid antigens, laminin, and type IV collagen in corneal epithelium. Invest Ophthalmol Vis Sci 1981; 21: 879-882.
2. Sugrue SP, Hay ED Interaction of embryonic corneal epithelium with exogenous collagen, laminin, and fibronectin: Role of endogenous protein synthesis. Dev Biol 1982; 92: 97-106.
3. Marshall GE, Konstas AG, Lee WR Immunogold fine structural localization of extracellular matrix components in aged human cornea. I. Types I-IV collagen and laminin. Graefes Arch Clin Exp Ophthalmol 1991; 229: 157-163.
4. Sakamoto K. Histological study on the innervation of the human cornea. Tohoku J Exp Med 1951; 54: 105-114.
5. Mensher JH. Corneal nerves. Surv Ophthalmol 1974; 19: 1-18.
6. Miller NR. Anatomy and physiology of the trigeminal nerve. In: Miller NR ed. Walsh and Hoyt's: Clinical neuro-ophthalmology. Baltimore, MD, Williams & Wilkins, 1985, pp 999-1043.
7. Muller LJ, Vrensen GF, Pels L, et al. Architecture of human corneal nerves. Invest Ophthalmol Vis Sci 1997; 38: 985-994.
8. Thoft RA, Friend J, Murphy HS Ocular surface epithelium and corneal vascularization in rabbits. I. The role of wounding. Invest Ophthalmol Vis Sci 1979; 18: 85-92.
9. Kurpakus-Wheater M., Kernacki KA, Hazlett LD Maintaining corneal integrity how the "window" stays clear. Prog Histochem Cytochem 2001; 36: 185-259.
10. Kuwabara T, Perkins DG, Cogan DG Sliding of the epithelium in experimental corneal wounds. Invest Ophthalmol 1976; 15: 4-14.
11. Buck RC. Cell migration in repair of mouse corneal epithelium. Invest Ophthalmol Vis Sci 1979; 18: 767-784.
12. Hanna C. Proliferation and migration of epithelial cells during corneal wound repair in the rabbit and the rat. Am J Ophthalmol 1966; 61: 55-63.
13. Matsuda H, Smelser GK Electron microscopy of corneal wound healing. Exp Eye Res 1973; 16: 427-442.
14. Dawson CR, Togni B. Herpes simplex eye infections: Clinical manifestations, pathogenesis and management. Surv Ophthalmol 1976; 21: 121-135.
15. Jones BR, Falcon MG, Williams H.P., et al. Objectives in therapy of herpetic eye disease. Trans Ophthalmol Soc U K 1977; 97: 305-313.
16. Hyndiuk RA, Kazarian EL, Schultz R.O., et al. Neurotrophic corneal ulcers in diabetes mellitus. Arch Ophthalmol 1977; 95: 2193-2196.
17. Cavanagh HD, Colley AM The molecular basis of neurotrophic keratitis. Acta Ophthalmol Suppl 1989; 192: 115-134.
18. Daniele S, Gilbard JP, Schepens CL Treatment of persistent epithelial defects in neurotrophic keratitis with epidermal growth factor: A preliminary open study. Graefes Arch Clin Exp Ophthalmol 1992; 230: 314-317.
19. Garcia-Hirschfeld J., Lopez-Briones LG, Belmonte C. Neurotrophic influences on corneal epithelial cells. Exp Eye Res 1994; 59: 597-605.
20. Brightbill FS, Myers FL, Bresnick GH Postvitrectomy keratopathy. Am J Ophthalmol 1978; 85: 651-655.
21. Snip RC, Thoft RA, Tolentino FI Similar epithelial healing rates of the corneas of diabetic and nondiabetic patients. Am J Ophthalmol 1980; 90: 463-468.
22. Schultz RO, Van Horn DL, Peters MA, et al. Diabetic keratopathy. Trans Am Ophthalmol Soc 1981; 79: 180-199.
23. Schultz RO, Peters MA, Sobocinski K, et al. Diabetic keratopathy as a manifestation of peripheral neuropathy. Am J Ophthalmol 1983; 96: 368-371.
24. Schultz RO, Peters MA, Sobocinski K, et al. Diabetic corneal neuropathy. Trans Am Ophthalmol Soc 1983; 81: 107-124.
25. Ohji M, Mandarino L, SundarRaj N., et al. Corneal epithelial cell attachment with endogenous laminin and fibronectin. Invest Ophthalmol Vis Sci 1993; 34: 2487-2492.
26. Cameron JD, Hagen ST, Waterfield R.R., et al. Effects of matrix proteins on rabbit corneal epithelial cell adhesion and migration. Curr Eye Res 1988; 7: 293-301.
27. Murakami J, Nishida T, Otori T. Coordinated appearance of beta 1 integrins and fibronectin during corneal wound healing. J Lab Clin Med 1992; 120: 86-93.
28. Nishida T. Role of fibronectin in corneal epithelial wound healing. In: Cavanagh H, ed. The Cornea: Transductions of the World Congress on the Cornea III. New York, Raven Press, 1988, pp 619-625.
29. Nishida T, Nakagawa S. Expression of fibronectin receptors in corneal epithelial cells. In: Beuerman R, Crosson C, Kaufman H, eds. Healing Processes in the Cornea. The Woodlands, Texas, The Portfolio Publishing Co., 1989, pp 127-135.
30. Nakamura M, Nishida T. Role of integrin and fibronectin in corneal epithelial migration. Jpn J Ophthalmol 1994; 38: 246-251. (Pubitemid 24323635)
31. Nishida T, Nakagawa S, Ohashi Y., et al. Fibronectin in corneal wound healing: Appearance in cultured rabbit cornea. Jpn J Ophthalmol 1982; 26: 410-415.
32. Nishida T, Nakagawa S, Awata T., et al. Fibronectin promotes epithelial migration of cultured rabbit cornea in situ. J Cell Biol 1983; 97: 1653-1657.
33. Nishida T, Nakagawa S, Nishibayashi C., et al. Fibronectin enhancement of corneal epithelial wound healing of rabbits in vivo. Arch Ophthalmol 1984; 102: 455-456.
34. Suda T, Nishida T, Ohashi Y., et al. Fibronectin appears at the site of corneal stromal wound in rabbits. Curr Eye Res 1981; 1: 553-556.
35. Nishida T, Ohashi Y, Inoue Y., et al. Dynamics of fibronectin in corneal wound healing: Immunohistochemical study of experimental bullous keratopathy in rabbits. Cornea 1982; 1: 311-317.
36. Nishida T, Nakagawa S, Awata T., et al. Rapid preparation of purified autologous fibronectin eyedrops from patient's plasma. Jpn J Ophthalmol 1982; 26: 416-424.
37. Nishida T, Ohashi Y, Awata T., et al. Fibronectin: A new therapy for corneal trophic ulcer. Arch Ophthalmol 1983; 101: 1046-1048.
38. Nishida T, Nakagawa S, Awata T., et al. Fibronectin eyedrops for traumatic recurrent corneal lesion. Lancet 1983; 2: 521-522.
39. Nishida T, Nakagawa S, Manabe R. Clinical evaluation of fibronectin eyedrops on epithelial disorders after herpetic keratitis. Ophthalmology 1985; 92: 213-216.
40. Nishida T, Yagi J, Fukuda M., et al. Spontaneous persistent epithelial defects after cataract surgery. Cornea 1987; 6: 32-37.
41. Nishida T, Nakamura M, Ofuji K., et al. Synergistic effects of substance P with insulin-like growth factor-1 on epithelial migration of the cornea. J Cell Physiol 1996; 169: 159-166.
42. Kahl BF, Reid TW Substance P and the eye. Prog Retin Eye Res 1995; 14: 473-504.
43. Pernow B. Substance P. Pharmacol Rev 1983; 35: 85-141.
44. Payan DG. Neuropeptides and inflammation: The role of substance P. Annu Rev Med 1989; 40: 341-352.
45. Otsuka M, Yoshioka K. Neurotransmitter functions of mammalian tachykinins. Physiol Rev 1993; 73: 229-308.
46. Nakamura M, Ofuji K, Chikama T., et al. The NK1 receptor and its participation in the synergistic enhancement of corneal epithelial migration by substance P and insulin-like growth factor-1. Br J Pharmacol 1997; 120: 547-552.
47. Nakamura M, Chikama T, Nishida T. Synergistic effect with Phe-Gly-Leu-Met-NH2 of the C-terminal of substance P and insulin-like growth factor-1 on epithelial wound healing of rabbit cornea. Br J Pharmacol 1999; 127: 489-497.
48. Nakamura M, Chikama TI, Nishida T. Characterization of insulin-like growth factor-1 receptors in rabbit corneal epithelial cells. Exp Eye Res 2000; 70: 199-204.
49. Yamada N, Yanai R, Nakamura M., et al. Role of the C domain of IGFs in synergistic promotion, with a substance P-derived peptide, of rabbit corneal epithelial wound healing. Invest Ophthalmol Vis Sci 2004; 45: 1125-1131.
50. Yamada N, Yanai R, Kawamoto K., et al. Promotion of corneal epithelial wound healing by a tetrapeptide (SSSR) derived from IGF-1. Invest Ophthalmol Vis Sci 2006; 47: 3286-3292.
51. Nakamura M, Ofuji K, Chikama T., et al. Combined effects of substance P and insulin-like growth factor-1 on corneal epithelial wound closure of rabbit in vivo. Curr Eye Res 1997; 16: 275-278.
52. Nagano T, Nakamura M, Nakata K., et al. Effects of substance P and IGF-1 in corneal epithelial barrier function and wound healing in a rat model of neurotrophic keratopathy. Invest Ophthalmol Vis Sci 2003; 44: 3810-3815. (Pubitemid 37047950)
53. Nakamura M, Kawahara M, Nakata K., et al. Restoration of corneal epithelial barrier function and wound healing by substance P and IGF-1 in rats with capsaicin-induced neurotrophic keratopathy. Invest Ophthalmol Vis Sci 2003; 44: 2937-2940. (Pubitemid 36759755)
54. Nakamura M, Nagano T, Chikama T., et al. Up-regulation of phosphorylation of focal adhesion kinase and paxillin by combination of substance P and IGF-1 in SV-40 transformed human corneal epithelial cells. Biochem Biophys Res Commun 1998; 242: 16-20.
55. Nakamura M, Chikama T, Nishida T. Up-regulation of integrin alpha 5 expression by combination of substance P and insulin-like growth factor-1 in rabbit corneal epithelial cells. Biochem Biophys Res Commun 1998; 246: 777-782.
56. Chikama T, Nakamura M, Nishida T. Up-regulation of integrin alpha5 by a C-terminus four-amino-acid sequence of substance P (phenylalanineglycine- leucine-methionine- amide) synergistically with insulin-like growth factor-1 in SV-40 transformed human corneal epithelial cells. Biochem Biophys Res Commun 1999; 255: 692-697.
57. Matsui H, Kumano Y, Zushi I., et al. Corneal sensation after correction of myopia by photorefractive keratectomy and laser in situ keratomileusis. J Cataract Refract Surg 2001; 27: 370-373.
58. Kumano Y, Matsui H, Zushi I., et al. Recovery of corneal sensation after myopic correction by laser in situ keratomileusis with a nasal or superior hinge. J Cataract Refract Surg 2003; 29: 757-761.
59. Saito J, Enoki M, Hara M., et al. Correlation of corneal sensation, but not of basal or reflex tear secretion, with the stage of diabetic retinopathy. Cornea 2003; 22: 15-18.
60. Chikama T, Fukuda K, Morishige N., et al. Treatment of neurotrophic keratopathy with substance-P-derived peptide (FGLM) and insulin-like growth factor I. Lancet 1998; 351: 1783-1784.
61. Brown SM, Lamberts DW, Reid T.W., et al. Neurotrophic and anhidrotic keratopathy treated with substance P and insulinlike growth factor 1. Arch Ophthalmol 1997; 115: 926-927.
62. Morishige N, Komatsubara T, Chikama T., et al. Direct observation of corneal nerve fibres in neurotrophic keratopathy by confocal biomicroscopy. Lancet 1999; 354: 1613-1614.
63. Nishida T, Chikama T, Morishige N., et al. Persistent epithelial defects due to neurotrophic keratopathy treated with a substance p-derived peptide and insulin-like growth factor 1. Jpn J Ophthalmol 2007; 51: 442-447.
64. Yamada N, Matsuda R, Morishige N., et al. Open clinical study of eye-drops containing tetrapeptides derived from substance P and insulin-like growth factor-1 for treatment of persistent corneal epithelial defects associated with neurotrophic keratopathy. Br J Ophthalmol 2008; 92: 896-900.
65. Chikamoto N, Chikama T, Yamada N., et al. Efficacy of substance P and insulin-like growth factor-1 peptides for preventing postsurgical superficial punctate keratopathy in diabetic patients. Jpn J Ophthalmol 2009; 53: 464-469.