Grape seed extract enhances eNOS expression and NO production through regulating calcium-mediated AKT phosphorylation in H2O2-treated endothelium

Cell Biology International

Volumn 34, Issue 10, 2010, Pages 1055-1061

  Feng, Zhe ^a   Wei, Ri Bao ^a   Hong, Quan ^a   Cui, Shao Yuan ^a   Chen, Xiang Mei ^a  

^a CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

Calcium; Endothelial nitric oxide synthase; Grape seed extract; Nitric oxide; Reactive oxygen species; Vascular endothelial cell

Indexed keywords

2 AMINOETHOXYDIPHENYLBORANE; CALCIUM; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GRAPE SEED EXTRACT; HYDROGEN PEROXIDE; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR; NITRIC OXIDE; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; THAPSIGARGIN;

ARTICLE; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CALCIUM TRANSPORT; CELL PROTECTION; CONCENTRATION RESPONSE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DRUG MECHANISM; ENDOTHELIUM CELL; ENDOTHELIUM INJURY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; EXTRACELLULAR CALCIUM; HUMAN; HUMAN CELL; MOLECULAR MECHANICS; PROTEIN EXPRESSION; UMBILICAL VEIN; UPREGULATION; VASCULAR ENDOTHELIUM;

BIFLAVONOIDS; BORON COMPOUNDS; CALCIUM; CATECHIN; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; GENE EXPRESSION REGULATION; GRAPE SEED EXTRACT; HUMANS; HYDROGEN PEROXIDE; INOSITOL 1,4,5-TRISPHOSPHATE; INOSITOL 1,4,5-TRISPHOSPHATE RECEPTORS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; PHOSPHORYLATION; PROANTHOCYANIDINS; PROTO-ONCOGENE PROTEINS C-AKT; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; THAPSIGARGIN; UMBILICAL VEINS; UP-REGULATION;

VITACEAE;

EID: 77957574250     PISSN: 10656995     EISSN: 10958355     Source Type: Journal    
DOI: 10.1042/CBI20100054     Document Type: Article

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