Time-dependent hypoglycemic and hypolipidemic effect of allium ascalonicum L. feeding in diabetic rats

Journal of Babol University of Medical Sciences

Volumn 12, Issue 1, 2010, Pages 16-23

  Fallahi, F ^a   Roghani, M ^a   Bagheri, A ^a  

^a SHAHED UNIVERSITY   (Iran)

Author keywords

Allium ascalonicum; Diabetes mellitus; Hypoglycemic; Hypolipidemic

Indexed keywords

ALLIUM ASCALONICUM EXTRACT; ANTIDIABETIC AGENT; ANTILIPEMIC AGENT; CHOLESTEROL; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PLANT EXTRACT; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DIABETES MELLITUS; DISEASE MODEL; EXPERIMENTAL STUDY; GLUCOSE BLOOD LEVEL; MALE; NONHUMAN; RAT; STREPTOZOCIN DIABETES; TRIACYLGLYCEROL BLOOD LEVEL;

EID: 77957571898     PISSN: 15614107     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Tripathi BK, Srivastava AK. Diabetes mellitus: complications and therapeutics. Med Sci Monit 2006;12(7):RA130-47.
2. Azizi F, Madjid M, Rahmani M, Emami H, Mirmiran P, Hadjipour R. Tehran Lipid and Glucose Study (TLGS): Rationale and design. Iranian J Endocrinol Metab 2000;6(2):77-86.
3. Wandell PE. Quality of life of patients with diabetes mellitus. An overview of research in primary health care in the Nordic countries. Scand J Prim Health Care 2005;23(2):68-74.
4. Suji G, Sivakami S. Approaches to the treatment of diabetes mellitus: an overview. Cell Mol Biol (Noisy-le-grand) 2003;49(4):635-9.
5. Shapiro K, Gong WC. Natural products used for diabetes. J Am Pharm Assoc (Wash) 2002;42(2):217-26.
6. Owoyele BV, Alabi OT, Adebayo JO, Soladoyea AO, Abioyeb AI, Jimohb SA. Haematological evaluation of ethanolic extract of Allium ascalonicum in male albino rats. Fitoterapia 2004;75(3-4):322-6.
7. Jalal R, Bagheri SM, Moghimi A, Rasuli MB. Hypoglycemic effect of aqueous shallot and garlic extracts in rats with fructose-induced insulin resistance. J Clin Biochem Nutr 2007;41(3):218-23.
8. Wongmekiat O, Leelarugrayub N, Thamprasert K. Beneficial effect of shallot (Allium ascalonicum L.) extract on cyclosporine nephrotoxicity in rats. Food Chem Toxicol 2008;46(5):1844-50.
9. Ashraf R, Aamir K, Shaikh AR, Ahmed T Effects of garlic on dyslipidemia in patients with type 2 diabetes mellitus. J Ayub Med Coll Abbottabad 2005;17(3):60-4.
10. Baluchnejadmojarad T, Roghani M. Garlic extract attenuates time-dependent changes in the reactivity of isolated aorta in streptozotocin-diabetic rats. Life Sci 2003;73(18):2281-9.
11. Swanston-Flatt SK, Day C, Bailey CJ, Flatt PR. Evaluation of traditional plant treatments for diabetes: studies in streptozotocin diabetic mice. Acta Diabetologica Latina 1989;26(1):51-5.
12. Nitta A, Murai R, Suzuki N, Ito H, Nomoto H, Katoh G, Furukawa Y, Furukawa S. Diabetic neuropathies in brain are induced by deficiency of BDNF. Neurotoxicol Teratol 2002;24(5):695-701.
13. Choi JS, Yokozawa T, Oura H. Improvement of hyperglycemia and hyperlipemia in streptozotocin-diabetic rats by a methanolic extract of Prunus daidiana stems and its main component, prunin. Planta Medica 1991;57(3):208-11.
14. Yanardag R, Bolkent S, Ozsoy-Sacan O, Karabulut-Bulan O. The effect of chard (Beta vulgaris L. var. cicla) extract on the kidney tissue, serum urea, and creatinine levels of diabetic rats. Phytother Res 2002;16(8):758-61.
15. Leelarungrayub N, Rattanapanone V, Chanarat N, Gebicki JM. Quantitative evaluation of the antioxidant properties of garlic and shallot preparations. Nutrition 2006;22(3):266-74.
16. Su HC, Hung LM, Chen JK. Resveratrol, a red wine antioxidant, possesses an insulin-like effect in streptozotocin-induced diabetic rats. Am J Physiol Endocrinol Metab 2006; 290:E1339-46.
17. Chia C, Chena W, Chic T, Kuod T, Leeb S, Chenge J, Sua M. Phosphatidylinositol-3-kinase is involved in the antihyperglycemic effect induced by resveratrol in streptozotocin-induced diabetic rats. Life Sci 2007;80(18):1713-20.
18. Petit PR, Sauvaire YD, Hillaire-Buys DM, Leconte OM, Baissac YG, Ponsin GR, et al. Steroid saponins from fenugreek seeds: extraction, purification, and pharmacological investigation on feeding behavior and plasma cholesterol. Steroids 1995;60(10):674-80.
19. Chen ZH, Li J, Liu J, et al. Saponins isolated from the root of Panax notoginseng showed significant anti-diabetic effects in KK-ay mice. Am J Chin Med 2008;36(5):939-51.
20. Pushparaj PN, Low HK, Manikandan J, Tan BK, Tan CH. Anti-diabetic effects of Cichorium intybus in streptozotocin-induced diabetic rats. J Ethnopharmacol 2007;111(2):430-4.
21. Valcheva-Kuzmanova S, Kuzmanov K, Tancheva S, Belcheva A Hypoglycemic and hypolipidemic effects of Aronia melanocarpa fruit juice in streptozotocin- induced diabetic rats. Methods Find Exp Clin Pharmacol 2007;29(2): 101-5.
22. Fattorusso E, Iorizzi M, Lanzotti V, Taglialatela-Scafati O. Chemical composition of shallot (Allium ascalonicum Hort). J Agric Food Chem 2002;50(20):5686-90.
23. Daisy P, Eliza J, Mohamed Farook KA. Hypoglycemic and hypolipidemic effect of a novel Gymnemic triacetate on STZ-induced diabetic rats. Phytomedicine 2009. [in Press]
24. Zhao HL, Sim JS, Shim SH, Ha YW, Kang SS, Kim YS. Antiobese and hypolipidemic effects of platycodin saponins in diet-induced obese rats: evidences for lipase inhibition and calorie intake restriction. Int J Obes (Lond) 2005;29(8):983-90.