Clusterin immunoexpression and its clinical significance in patients with non-small cell lung cancer

Lung

Volumn 188, Issue 5, 2010, Pages 423-431

  Li, Hecheng ^a,b   Liu, Shilei ^a,b   Zhu, Xiaoli ^a,b   Yang, Shuo ^a,b   Xiang, Jiaqing ^a,b   Chen, Haiquan ^a,b  

^a FUDAN UNIVERSITY SHANGHAI CANCER CENTER   (China)

^b FUDAN UNIVERSITY   (China)

Author keywords

Chemotherapy; Clusterin; Immunostaining; Non small cell lung cancer; Prognosis

Indexed keywords

CLUSTERIN; ISOPROTEIN;

ADENOCARCINOMA; ADULT; AGED; APOPTOSIS; ARTICLE; CANCER CHEMOTHERAPY; CANCER STAGING; CELL NUCLEUS; CHINESE; CLINICAL FEATURE; COMPLEMENT ACTIVATION; CONTROLLED STUDY; CYTOPLASM; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LIPID TRANSPORT; LUNG NON SMALL CELL CANCER; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE ANALYSIS; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN POLYMORPHISM; REPRODUCTION; TISSUE GROWTH; UNIVARIATE ANALYSIS;

ADENOCARCINOMA; CARCINOMA, NON-SMALL-CELL LUNG; CLUSTERIN; FEMALE; HUMANS; LUNG NEOPLASMS; MALE; MIDDLE AGED; PROGNOSIS; PROTEIN ISOFORMS;

EID: 77957571861     PISSN: 03412040     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00408-010-9248-1     Document Type: Article

References (25)

1. ME Rosenberg J Silkensen 1995 Clusterin: physiologic and pathophysiologic considerations Int J Biochem Cell Biol 27 633 645 1:CAS:528:DyaK2MXns1eitL8%3D 10.1016/1357-2725(95)00027-M 7648419
2. J Lakins SA Bennett JH Chen, et al. 1998 Clusterin biogenesis is altered during apoptosis in the regressing rat ventral prostate J Biol Chem 273 27887 27895 1:CAS:528:DyaK1cXntVCmtL4%3D 10.1074/jbc.273.43.27887 9774400 (Pubitemid 28496077)
3. KB Reddy G Jin MC Karode JA Harmony PH Howe 1996 Transforming growth factor beta (TGF beta)-induced nuclear localization of apolipoprotein J/clusterin in epithelial cells Biochemistry 35 6157 6163 1:CAS:528: DyaK28XisV2jsLs%3D 10.1021/bi952981b 8634259 (Pubitemid 26147589)
4. CR Yang K Leskov K Hosley-Eberlein, et al. 2000 Nuclear clusterin/XIP8, an x-ray-induced Ku70-binding protein that signals cell death Proc Natl Acad Sci USA 97 5907 5912 1:CAS:528:DC%2BD3cXjvFaktbc%3D 10.1073/pnas.97.11.5907 10823943 (Pubitemid 30367497)
5. ME Gleave H Miyake T Zellweger, et al. 2001 Use of antisense oligonucleotides targeting the antiapoptotic gene, clusterin/testosterone- repressed prostate message 2, to enhance androgen sensitivity and chemosensitivity in prostate cancer Urology 58 39 49 1:STN:280: DC%2BD3Mvlslegsg%3D%3D 10.1016/S0090-4295(01)01241-9 11502446 (Pubitemid 32743407)
6. H Miyake I Hara S Kamidono ME Gleave 2001 Synergistic chemosensitization and inhibition of tumor growth and metastasis by the antisense oligodeoxynucleotide targeting clusterin gene in a human bladder cancer model Clin Cancer Res 7 4245 4252 1:CAS:528:DC%2BD38XltFSgtQ%3D%3D 11751526
7. T Criswell D Klokov M Beman JP Lavik DA Boothman 2003 Repression of IR-inducible clusterin expression by the p53 tumor suppressor protein Cancer Biol Ther 2 372 380 1:CAS:528:DC%2BD3sXps1Kgtrw%3D 14508108
8. L Debure JL Vayssiere V Rincheval F Loison Y Le Drean D Michel 2003 Intracellular clusterin causes juxtanuclear aggregate formation and mitochondrial alteration J Cell Sci 116 3109 3121 1:CAS:528:DC%2BD3sXmslKltro%3D 10.1242/jcs.00619 12799419 (Pubitemid 37038960)
9. J O'Sullivan L Whyte J Drake M Tenniswood 2003 Alterations in the post-translational modification and intracellular trafficking of clusterin in MCF-7 cells during apoptosis Cell Death Differ 10 914 927 10.1038/sj.cdd.4401254 12867999 (Pubitemid 36939702)
10. M Scaltriti A Santamaria R Paciucci S Bettuzzi 2004 Intracellular clusterin induces G2-M phase arrest and cell death in PC-3 prostate cancer cells Cancer Res 64 6174 6182 1:CAS:528:DC%2BD2cXntFClsbg%3D 10.1158/0008-5472.CAN- 04-0920 15342402 (Pubitemid 39129419)
11. C Cao ET Shinohara H Li, et al. 2005 Clusterin as a therapeutic target for radiation sensitization in a lung cancer model Int J Radiat Oncol Biol Phys 63 1228 1236 1:CAS:528:DC%2BD2MXhtFKhsL3P 16253777 (Pubitemid 41505304)
12. SH Landis T Murray S Bolden PA Wingo 1998 Cancer statistics, 1998 CA Cancer J Clin 48 6 29 1:STN:280:DyaK1c7htFGrtg%3D%3D 10.3322/canjclin.48.1.6 9449931
13. JM Albert A Gonzalez PP Massion, et al. 2007 Cytoplasmic clusterin expression is associated with longer survival in patients with resected non-small cell lung cancer Cancer Epidemiol Biomarkers Prev 16 1845 1851 1:CAS:528:DC%2BD2sXhtVaktr7O 10.1158/1055-9965.EPI-07-0146 17855704 (Pubitemid 47450516)
14. YK Kang SW Hong H Lee WH Kim 2004 Overexpression of clusterin in human hepatocellular carcinoma Hum Pathol 35 1340 1346 1:CAS:528:DC%2BD2cXhtVKltLrP 10.1016/j.humpath.2004.07.021 15668890 (Pubitemid 39601573)
15. T Kurahashi M Muramaki K Yamanaka I Hara H Miyake 2005 Expression of the secreted form of clusterin protein in renal cell carcinoma as a predictor of disease extension BJU Int 96 895 899 1:CAS:528:DC%2BD2MXhtFGrt73I 10.1111/j.1464-410X.2005.05733.x 16153225 (Pubitemid 41391404)
16. H Miyake M Muramaki T Kurahashi, et al. 2006 Expression of clusterin in prostate cancer correlates with Gleason score but not with prognosis in patients undergoing radical prostatectomy without neoadjuvant hormonal therapy Urology 68 609 614 10.1016/j.urology.2006.03.017 16979705 (Pubitemid 44436479)
17. M Redondo E Villar J Torres-Munoz T Tellez M Morell CK Petito 2000 Overexpression of clusterin in human breast carcinoma Am J Pathol 157 393 399 1:CAS:528:DC%2BD3cXlvFyru7s%3D 10934144
18. S Kruger A Mahnken I Kausch AC Feller 2006 Value of clusterin immunoreactivity as a predictive factor in muscle-invasive urothelial bladder carcinoma Urology 67 105 109 10.1016/j.urology.2005.04.043 16413343 (Pubitemid 43069266)
19. H Miyake K Yamanaka M Muramaki T Kurahashi M Gleave I Hara 2005 Enhanced expression of the secreted form of clusterin following neoadjuvant hormonal therapy as a prognostic predictor in patients undergoing radical prostatectomy for prostate cancer Oncol Rep 14 1371 1375 1:CAS:528:DC%2BD2MXhtF2mtrjL 16211311
20. MJ Xie Y Motoo SB Su, et al. 2002 Expression of clusterin in human pancreatic cancer Pancreas 25 234 238 10.1097/00006676-200210000-00004 12370533
21. JY Djeu S Wei 2009 Clusterin and chemoresistance Adv Cancer Res 105 77 92 1:CAS:528:DC%2BC3cXmt1OqtA%3D%3D 10.1016/S0065-230X(09)05005-2 19879424
22. T Zellweger H Miyake LV July M Akbari S Kiyama ME Gleave 2001 Chemosensitization of human renal cell cancer using antisense oligonucleotides targeting the antiapoptotic gene clusterin Neoplasia 3 360 367 1:CAS:528:DC%2BD3MXntVSmurw%3D 10.1038/sj.neo.7900174 11571636 (Pubitemid 32801886)
23. T Zellweger H Miyake S Cooper, et al. 2001 Antitumor activity of antisense clusterin oligonucleotides is improved in vitro and in vivo by incorporation of 2′-O-(2-methoxy)ethyl chemistry J Pharmacol Exp Ther 298 934 940 1:CAS:528:DC%2BD3MXmtFKmsbs%3D 11504787
24. A So S Sinnemann D Huntsman L Fazli M Gleave 2005 Knockdown of the cytoprotective chaperone, clusterin, chemosensitizes human breast cancer cells both in vitro and in vivo Mol Cancer Ther 4 1837 1849 1:CAS:528: DC%2BD2MXhtlCnsrrE 10.1158/1535-7163.MCT-05-0178 16373699 (Pubitemid 43056967)
25. LV July E Beraldi A So, et al. 2004 Nucleotide-based therapies targeting clusterin chemosensitize human lung adenocarcinoma cells both in vitro and in vivo Mol Cancer Ther 3 223 232 1:CAS:528:DC%2BD2cXitFCnsrg%3D 15026542