Frameshift mutation of MARS gene encoding an aminoacyl-tRNA synthetase in gastric and colorectal carcinomas with microsatellite instability

Gut and Liver

Volumn 4, Issue 3, 2010, Pages 430-431

  Park, Sang Wook ^a   Kim, Sung Soo ^a   Yoo, Nam Jin ^a   Lee, Sug Hyung ^a  

^a The Catholic University of Korea College of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID TRANSFER RNA LIGASE;

CARBOXY TERMINAL SEQUENCE; COLORECTAL CARCINOMA; DNA SEQUENCE; DOWN REGULATION; FRAMESHIFT MUTATION; GENE AMPLIFICATION; HUMAN; LETTER; MICROSATELLITE INSTABILITY; POLYMERASE CHAIN REACTION; PROTEIN PROTEIN INTERACTION; RNA TRANSLATION; STOMACH CARCINOMA;

EID: 77957568534     PISSN: 19762283     EISSN: None     Source Type: Journal    
DOI: 10.5009/gnl.2010.4.3.430     Document Type: Letter

References (5)

1. Lee SW, Cho BH, Park SG, Kim S. Aminoacyl-tRNA synthetase complexes: beyond translation. J Cell Sci 2004;117 (Pt 17):3725-3734.
2. Park BJ, Kang JW, Lee SW, et al. The haploinsufficient tumor suppressor p18 upregulates p53 via interactions with ATM/ATR. Cell 2005;120:209-221.
3. Imai K, Yamamoto H. Carcinogenesis and microsatellite instability: the interrelationship between genetics and epigenetics. Carcinogenesis 2008;29:673-680.
4. Lee JW, Soung YH, Kim SY, et al. PIK3CA gene is frequently mutated in breast carcinomas and hepatocellular carcinomas. Oncogene 2005;24:1477-1480.
5. Ko YG, Kang YS, Kim EK, Park SG, Kim S. Nucleolar localization of human methionyl-tRNA synthetase and its role in ribosomal RNA synthesis. J Cell Biol 2000;149:567-574.