메뉴 건너뛰기




Volumn 25, Issue 10, 2010, Pages 1687-1691

Large-scale population analysis reveals an extremely low threshold for "non-healthy" alanine aminotransferase that predicts diabetes mellitus

Author keywords

diabetes mellitus; healthy alanine aminotransferase; liver; normal alanine aminotransferase

Indexed keywords

ALANINE AMINOTRANSFERASE; CHOLESTEROL; TRIACYLGLYCEROL; GLUCOSE; HEMOGLOBIN A1C;

EID: 77957563723     PISSN: 08159319     EISSN: 14401746     Source Type: Journal    
DOI: 10.1111/j.1440-1746.2010.06369.x     Document Type: Article
Times cited : (12)

References (23)
  • 1
    • 65149091998 scopus 로고    scopus 로고
    • The asymptomatic outpatient with abnormal liver function tests
    • Krier M, Ahmed A. The asymptomatic outpatient with abnormal liver function tests. Clin. Liver Dis. 2009 13 : 167 177.
    • (2009) Clin. Liver Dis. , vol.13 , pp. 167-177
    • Krier, M.1    Ahmed, A.2
  • 2
    • 0029864836 scopus 로고    scopus 로고
    • Evaluating asymptomatic patients with abnormal liver function test results
    • Theal RM, Scott K. Evaluating asymptomatic patients with abnormal liver function test results. Am. Fam. Physician 1996 53 : 2111 2119.
    • (1996) Am. Fam. Physician , vol.53 , pp. 2111-2119
    • Theal, R.M.1    Scott, K.2
  • 3
    • 73149100612 scopus 로고    scopus 로고
    • Variability in the upper limit of normal for serum alanine aminotransferase levels: A statewide study
    • Dutta A, Saha C, Johnson CS, Chalasani N. Variability in the upper limit of normal for serum alanine aminotransferase levels: a statewide study. Hepatology 2009 50 : 1957 1962.
    • (2009) Hepatology , vol.50 , pp. 1957-1962
    • Dutta, A.1    Saha, C.2    Johnson, C.S.3    Chalasani, N.4
  • 4
    • 13444282229 scopus 로고    scopus 로고
    • Liver enzyme alteration: A guide for clinicians
    • Giannini EG, Testa R, Savarino V. Liver enzyme alteration: a guide for clinicians. CMAJ 2005 172 : 367 379.
    • (2005) CMAJ , vol.172 , pp. 367-379
    • Giannini, E.G.1    Testa, R.2    Savarino, V.3
  • 5
    • 0034720287 scopus 로고    scopus 로고
    • Evaluation of abnormal liver-enzyme results in asymptomatic patients
    • Pratt DS, Kaplan MM. Evaluation of abnormal liver-enzyme results in asymptomatic patients. N. Engl. J. Med. 2000 342 : 1266 1271.
    • (2000) N. Engl. J. Med. , vol.342 , pp. 1266-1271
    • Pratt, D.S.1    Kaplan, M.M.2
  • 6
    • 0037223610 scopus 로고    scopus 로고
    • Defining nonalcoholic fatty liver disease: Implications for epidemiologic studies
    • Clark JM, Diehl AM. Defining nonalcoholic fatty liver disease: implications for epidemiologic studies. Gastroenterology 2003 124 : 248 250.
    • (2003) Gastroenterology , vol.124 , pp. 248-250
    • Clark, J.M.1    Diehl, A.M.2
  • 7
    • 0024593460 scopus 로고
    • The nature of unexplained chronic aminotransferase elevations of a mild to moderate degree in asymptomatic patients
    • Hay JE, Czaja AJ, Rakela J, Ludwig J. The nature of unexplained chronic aminotransferase elevations of a mild to moderate degree in asymptomatic patients. Hepatology 1989 9 : 193 197.
    • (1989) Hepatology , vol.9 , pp. 193-197
    • Hay, J.E.1    Czaja, A.J.2    Rakela, J.3    Ludwig, J.4
  • 8
    • 65449156905 scopus 로고    scopus 로고
    • NAFLD as a risk factor for the development of diabetes and the metabolic syndrome: An eleven-year follow-up study
    • Adams LA, Waters OR, Knuiman MW, Elliott RR, Olynyk JK. NAFLD as a risk factor for the development of diabetes and the metabolic syndrome: an eleven-year follow-up study. Am. J. Gastroenterol. 2009 104 : 861 867.
    • (2009) Am. J. Gastroenterol. , vol.104 , pp. 861-867
    • Adams, L.A.1    Waters, O.R.2    Knuiman, M.W.3    Elliott, R.R.4    Olynyk, J.K.5
  • 9
  • 10
    • 38749102436 scopus 로고    scopus 로고
    • Liver enzymes and risk of diabetes and cardiovascular disease: Results of the Firenze Bagno a Ripoli (FIBAR) study
    • Monami M, Bardini G, Lamanna C et al. Liver enzymes and risk of diabetes and cardiovascular disease: results of the Firenze Bagno a Ripoli (FIBAR) study. Metabolism 2008 57 : 387 392.
    • (2008) Metabolism , vol.57 , pp. 387-392
    • Monami, M.1    Bardini, G.2    Lamanna, C.3
  • 11
    • 7044274423 scopus 로고    scopus 로고
    • Elevated alanine aminotransferase predicts new-onset type 2 diabetes independently of classical risk factors, metabolic syndrome, and C-reactive protein in the west of Scotland coronary prevention study
    • Sattar N, Scherbakova O, Ford I et al. Elevated alanine aminotransferase predicts new-onset type 2 diabetes independently of classical risk factors, metabolic syndrome, and C-reactive protein in the west of Scotland coronary prevention study. Diabetes 2004 53 : 2855 2860.
    • (2004) Diabetes , vol.53 , pp. 2855-2860
    • Sattar, N.1    Scherbakova, O.2    Ford, I.3
  • 12
    • 33947169979 scopus 로고    scopus 로고
    • Alanine aminotransferase predicts coronary heart disease events: A 10-year follow-up of the Hoorn Study
    • Schindhelm RK, Dekker JM, Nijpels G et al. Alanine aminotransferase predicts coronary heart disease events: a 10-year follow-up of the Hoorn Study. Atherosclerosis 2007 191 : 391 396.
    • (2007) Atherosclerosis , vol.191 , pp. 391-396
    • Schindhelm, R.K.1    Dekker, J.M.2    Nijpels, G.3
  • 13
    • 0036263238 scopus 로고    scopus 로고
    • High alanine aminotransferase is associated with decreased hepatic insulin sensitivity and predicts the development of type 2 diabetes
    • Vozarova B, Stefan N, Lindsay RS et al. High alanine aminotransferase is associated with decreased hepatic insulin sensitivity and predicts the development of type 2 diabetes. Diabetes 2002 51 : 1889 1895. (Pubitemid 34564303)
    • (2002) Diabetes , vol.51 , Issue.6 , pp. 1889-1895
    • Vozarova, B.1    Stefan, N.2    Lindsay, R.S.3    Saremi, A.4    Pratley, R.E.5    Bogardus, C.6    Antonio Tataranni, P.7
  • 14
    • 33644823983 scopus 로고    scopus 로고
    • Hepatic enzymes, the metabolic syndrome, and the risk of type 2 diabetes in older men
    • Wannamethee SG, Shaper AG, Lennon L, Whincup PH. Hepatic enzymes, the metabolic syndrome, and the risk of type 2 diabetes in older men. Diabetes Care 2005 28 : 2913 2918.
    • (2005) Diabetes Care , vol.28 , pp. 2913-2918
    • Wannamethee, S.G.1    Shaper, A.G.2    Lennon, L.3    Whincup, P.H.4
  • 15
    • 57349163062 scopus 로고    scopus 로고
    • Aminotransferase levels and 20-year risk of metabolic syndrome, diabetes, and cardiovascular disease
    • 44 e1
    • Goessling W, Massaro JM, Vasan RS, D'Agostino RB, Sr., Ellison RC, Fox CS. Aminotransferase levels and 20-year risk of metabolic syndrome, diabetes, and cardiovascular disease. Gastroenterology 2008 135 : 1935 1944, 44 e1.
    • (2008) Gastroenterology , vol.135 , pp. 1935-1944
    • Goessling, W.1    Massaro, J.M.2    Vasan, R.S.3    D'Agostino Sr., R.B.4    Ellison, R.C.5    Fox, C.S.6
  • 17
    • 33845224953 scopus 로고    scopus 로고
    • In a population-based cohort of diabetes patients, men and women had similar risks for all-cause mortality
    • Shalev V, Chodick G, Bialik M, Green MS, Heymann AD. In a population-based cohort of diabetes patients, men and women had similar risks for all-cause mortality. J. Clin. Epidemiol. 2007 60 : 86 93.
    • (2007) J. Clin. Epidemiol. , vol.60 , pp. 86-93
    • Shalev, V.1    Chodick, G.2    Bialik, M.3    Green, M.S.4    Heymann, A.D.5
  • 18
    • 33645743113 scopus 로고    scopus 로고
    • Re-evaluation of serum alanine aminotransferase upper normal limit and its modulating factors in a large-scale population study
    • Kariv R, Leshno M, Beth-Or A et al. Re-evaluation of serum alanine aminotransferase upper normal limit and its modulating factors in a large-scale population study. Liver Int. 2006 26 : 445 450.
    • (2006) Liver Int. , vol.26 , pp. 445-450
    • Kariv, R.1    Leshno, M.2    Beth-Or, A.3
  • 19
    • 34247863931 scopus 로고    scopus 로고
    • Abnormal lipid and glucose metabolism in obesity: Implications for nonalcoholic fatty liver disease
    • Parekh S, Anania FA. Abnormal lipid and glucose metabolism in obesity: implications for nonalcoholic fatty liver disease. Gastroenterology 2007 132 : 2191 2207.
    • (2007) Gastroenterology , vol.132 , pp. 2191-2207
    • Parekh, S.1    Anania, F.A.2
  • 21
    • 17344363641 scopus 로고    scopus 로고
    • Factors associated with serum alanine transaminase activity in healthy subjects: Consequences for the definition of normal values, for selection of blood donors, and for patients with chronic hepatitis C. MULTIVIRC Group
    • Piton A, Poynard T, Imbert-Bismut F et al. Factors associated with serum alanine transaminase activity in healthy subjects: consequences for the definition of normal values, for selection of blood donors, and for patients with chronic hepatitis C. MULTIVIRC Group. Hepatology 1998 27 : 1213 1219.
    • (1998) Hepatology , vol.27 , pp. 1213-1219
    • Piton, A.1    Poynard, T.2    Imbert-Bismut, F.3
  • 22
    • 0037008087 scopus 로고    scopus 로고
    • Updated definitions of healthy ranges for serum alanine aminotransferase levels
    • Prati D, Taioli E, Zanella A et al. Updated definitions of healthy ranges for serum alanine aminotransferase levels. Ann. Intern. Med. 2002 137 : 1 10.
    • (2002) Ann. Intern. Med. , vol.137 , pp. 1-10
    • Prati, D.1    Taioli, E.2    Zanella, A.3
  • 23
    • 72549098792 scopus 로고    scopus 로고
    • Gamma-glutamyl transferase: A novel cardiovascular risk biomarker
    • Mason JE, Starke RD, Van Kirk JE. Gamma-glutamyl transferase: a novel cardiovascular risk biomarker. Prev. Cardiol. 2010 13 : 36 41.
    • (2010) Prev. Cardiol. , vol.13 , pp. 36-41
    • Mason, J.E.1    Starke, R.D.2    Van Kirk, J.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.