Variability in the upper limit of normal for serum alanine aminotransferase levels: A statewide study

Hepatology

Volumn 50, Issue 6, 2009, Pages 1957-1962

  Dutta, Anand ^a   Saha, Chandan ^a   Johnson, Cynthia S ^a   Chalasani, Naga ^a,b  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b INDIANA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANALYZER; ARTICLE; BLOOD ANALYSIS; CONTROLLED STUDY; ENZYME ANALYSIS; FEMALE; HUMAN; LABORATORY TEST; MALE; NORMAL VALUE; PRIORITY JOURNAL; UNITED STATES;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ALANINE TRANSAMINASE; CHILD; CHILD, PRESCHOOL; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; MALE; MIDDLE AGED; REFERENCE VALUES;

EID: 73149100612     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.23200     Document Type: Article

References (7)

1. Dufour DR, Lott JA, Nolte FS, Gretch DR, Koff RS, Seeff LB. Diagnosis and monitoring of hepatic injury. I. Performance characteristics of laboratory tests. Clin Chem 2000;46:2027-2049.
2. Kim H, Nam C, Jee S, Han K, Oh D, Suh I. Normal serum aminotransferase concentration and risk of mortality from liver disease: prospective cohort study. BMJ 2004;328:983
3. Kim WR, Benson JT, Therneau TM, Buritt MF, Melton LJ. Serum aminotransferase activity and risk of mortality in a U.S. community population. HEPATOLOGY 2008;47;880-887.
4. Ioannou G, Weiss N, Boyko E, Mozaffarian D. Elevated serum alanine aminotransferase activity and calculated risk of coronary artery disease in the United States. HEPATOLOGY 2006;43:1145-1151.
5. Kim WR, Flamm SL, Di Bisceglie AM, Bodenheimer HC; Public Policy Committee of the American Association for the Study of Liver Disease. Serum activity of alanine aminotransferase (ALT) as an indicator of health and disease. HEPATOLOGY 2008;47:1363-1373.
6. Horowitz GL, Altaie A, Boyd JC, Ceriotto F, Garg U, Horn P, et al. Defining, Establishing, and Verifying Reference Intervals in the Clinical Laboratory; Approved Guideline - Third Edition. Clinical and Laboratory Standards Institute C28-A3, volume 28(30), 2008.
7. Neuschwander-Tetri BA, Unalp A, Creer MH, Nonalcoholic steatohepatitis Clinical Research Network. Influence of local reference populations on upper limits of normal for serum alanine aminotransferase levels. Arch Intern Med 2008;24:663-666.