Safety evaluation of proanthocyanidin polymer-rich fraction obtained from stem bark of Stryphnodendron adstringens (BARBATIMO) for use as a pharmacological agent

Regulatory Toxicology and Pharmacology

Volumn 58, Issue 2, 2010, Pages 330-335

  Costa, Marco Antonio ^a   Ishida, Kelly ^b   Kaplum, Vanessa ^a   Koslyk, Éryca Danielle Alves ^a   de Mello, João Carlos Palazzo ^a   Ueda Nakamura, Tânia ^a   Filho, Benedito Prado Dias ^a   Nakamura, Celso Vataru ^a  

^a STATE UNIVERSITY OF MARINGÁ   (Brazil)

^b FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

Antifungal action; Antimutagenicity; Artemia salina; Cyclophosphamide; Genotoxicity; Herbal medicine; Micronucleus assay; Plant extracts; Stryphnodendron adstringens; Tannin; Vulvo vaginal candidiasis

Indexed keywords

CYCLOPHOSPHAMIDE; PLANT EXTRACT; POLYMER; PROANTHOCYANIDIN DERIVATIVE; STRYPHNODENDRON ADSTRINGENS EXTRACT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTEMIA; ARTEMIA SALINA; ARTICLE; BARK; BRAZIL; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; ERYTHROCYTE; FEMALE; GENOTOXICITY; LD 50; MALE; MEDICINAL PLANT; MICRONUCLEUS TEST; MOUSE; MUTAGENICITY; NONHUMAN; OUTBRED STRAIN; PLANT STEM; PRIORITY JOURNAL; RISK ASSESSMENT; STRYPHNODENDRON ADSTRINGENS; SURVIVAL; SWISS WEBSTER MOUSE; TOXICITY TESTING;

ANIMALS; CYCLOPHOSPHAMIDE; DOSE-RESPONSE RELATIONSHIP, DRUG; FABACEAE; FEMALE; MALE; MEDICINE, TRADITIONAL; MICE; MICRONUCLEUS TESTS; PLANT BARK; PLANT EXTRACTS; PLANT STEMS; POLYMERS; PROANTHOCYANIDINS;

ARTEMIA SALINA; MUS; MUS MUSCULUS; STRYPHNODENDRON ADSTRINGENS;

EID: 77957551801     PISSN: 02732300     EISSN: 10960295     Source Type: Journal    
DOI: 10.1016/j.yrtph.2010.07.006     Document Type: Article

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