Toxicity and characterization of cholinesterase-inhibition induced by diisopropyl fluorophosphate in Artemia salina larvae

Ecotoxicology and Environmental Safety

Volumn 72, Issue 3, 2009, Pages 775-780

  Sanchez Fortun S ^a   Barahona, M V ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

2 PAM; Artemia salina; Atropine; Diisopropyl fluorophosphate; Physostigmine; Pyridostigmine

Indexed keywords

ATROPINE; CHOLINESTERASE; DYFLOS; PHYSOSTIGMINE; PRALIDOXIME IODIDE; PYRIDOSTIGMINE;

AGE CLASS; ALKALOID; CRUSTACEAN; ENZYME ACTIVITY; INHIBITOR; LARVA; ORGANOPHOSPHATE; TOXICITY;

ACUTE TOXICITY; ANIMAL EXPERIMENT; ARTEMIA; ARTEMIA SALINA; ARTICLE; CHOLINESTERASE INHIBITION; CONTROLLED STUDY; DRUG EFFICACY; INHIBITION KINETICS; LARVA; LETHALITY; NONHUMAN; PROTECTION; TOXICITY TESTING;

ACUTE TOXICITY TESTS; ANIMALS; ARTEMIA; ATROPINE; CHOLINESTERASE INHIBITORS; CHOLINESTERASE REACTIVATORS; DRUG THERAPY, COMBINATION; ISOFLUROPHATE; LARVA; LONGEVITY; MUSCARINIC ANTAGONISTS; PHYSOSTIGMINE; PRALIDOXIME COMPOUNDS; PYRIDOSTIGMINE BROMIDE; WATER POLLUTANTS, CHEMICAL;

ARTEMIA; ARTEMIA SALINA;

EID: 59149093112     PISSN: 01476513     EISSN: 10902414     Source Type: Journal    
DOI: 10.1016/j.ecoenv.2007.11.004     Document Type: Article

References (24)

1. Barahona M.V., and Sánchez-Fortún S. Toxicity of carbamates on Artemia salina and the effect of atropine, BW284c51, iso-OMPA and 2-PAM on carbaryl toxicity. Environ. Pollut. 104 (1999) 469-476
2. Barahona M.V., and Sánchez-Fortún S. Protective effect induced by atropine, carbamates and 2-PAM on Artemia larvae exposed to fonofos and phosphamidon. Ecotoxicol. Environ. Saf. 66 (2007) 65-73
3. Barahona M.V., Sanz F., and Sánchez-Fortún S. Acute toxicity of different solvents in Artemia salina. Bull. Environ. Contam. Toxicol. 52 (1994) 766-771
4. Dawson R.M. Review of oximes available for treatment of nerve agent poisoning. J. Appl. Toxicol. 14 (1994) 317-331
5. Galli A., and Mori F. Protection of acetylcholinesterase by meptazinol in mice exposed to di-isopropyl fluorophosphate. Comparison with physostigmine. J. Pharm. Pharmacol. 43 (1991) 366-369
6. Janowsky D.S. Central anticholinergics to treat nerve agent poisoning. Lancet 359 (2002) 265-266
7. Janowsky D.S., Davis J.M., and Overstreet D.H. Antagonism of anticholinesterase (DFP) toxicity by donepezil plus scopolamine: a preliminary study. Pharmacol. Biochem. Behav. 77 (2004) 337-343
8. Lallement G., Foquin A., Dorandeu F., Baubichon D., and Carpentier P. Subchronic administration of various pretreatments of nerve gas poisoning: II. Compared efficacy against soman toxicity. Drug Chem. Toxicol. 24 (2001) 165-180
9. Lallement G., Demoncheoux J.P., Foquin A., Baubichon D., Galonnier M., and Clarencon D. Subchronic administration of pyridostigmine or huperzine to primates: compared efficacy against soman toxicity. Drug Chem. Toxicol. 25 (2002) 309-320
10. Leadbeater L., Inns R.H., and Rylands J.M. Treatment of poisoning by soman. Fundam. Appl. Toxicol. 5 (1985) S225-S231
11. Leikin J.B., Thomas R.G., Walter F.G., Klein R., and Meislin H.W. A review of nerve agent exposure for the critical care physician. Crit. Care Med. 10 (2002) 2346-2354
12. Litchfield PH., and Wilcoxon F. A simplified method of evaluating dose-effect experiments. J. Pharmacol. Exp. Ther. 96 (1949) 99-113
13. Miller S.A., Blick D.W., Kerenyi S.Z., and Murphy M.R. Efficacy of physostigmine as a pretreatment for organophosphate poisoning. Pharmacol. Biochem. Behav. 44 (1993) 343-347
14. Persoone G., Sorgeloos P., Roels G., and Jaspers E. The Brine Shrimp, Artemia (1980), Universa Press, Wetteren, Belgium
15. Persoone G., Van de Vell A., Van Steertegem M., and Nayer B. Predictive value for laboratory tests with aquatic invertebrates: influence of experimental conditions. Aquat. Toxicol. 14 (1989) 149-166
16. Philippens I.H., Melchers B.P., Olivier B., and Bruijnzeel P.L. Scopolamine augments the efficacy of physostigmine against soman poisoning in guinea pigs. Pharmacol. Biochem. Behav. 65 (2000) 175-182
17. Sánchez-Fortún S., and Barahona M.V. The use of carbamates, atropine and 2-PAM in the protection of Artemia salina against poisoning by carbophenotion. Environ. Toxicol. Chem. 20 (2001) 2008-2013
18. Sánchez-Fortún S., Sanz F., and Barahona M.V. Acute toxicities of selected insecticides to the aquatic arthropod Artemia salina. Bull. Environ. Contam. Toxicol. 54 (1995) 76-82
19. Sánchez-Fortún S., Sanz F., and Barahona M.V. Acute toxicity of several organophosphorous insecticidas and protection by cholinergic antagonists and 2-PAM on Artemia salina larvae. Arch. Environ. Contam. Toxicol. 31 (1996) 391-398
20. Sánchez-Fortún S., Sanz F., Santa-María A., Ros J.M., De Vicente M.L., Encinas T., Vinagre E., and Barahona M.V. Acute sensitivity of three age classes of Artemia salina larvae to seven chlorinated solvents. Bull. Environ. Contam. Toxicol. 59 (1997) 445-451
21. Solana R.P., Gennings D., Carter W.H.J., Anderson D., Lennox W.J., Carchman R.A., and Harris L.W. Evaluation of the efficacy of two carbamates, physostigmine and pyridostigmine, when used in conjunction for protection against organophosphate exposure. Fund. Appl. Toxicol. 15 (1990) 814-819
22. Taylor P. Anticholinesterase agents. In: Hardman J.G., and Limbird L.E. (Eds). The Pharmacological Basis of Therapeutics. third ed (1996), McGraw-Hill, New York 161-176
23. Van Voris, P., Cataldo, D.A., Ligotke, M.W., Fredrickson, J.K., Li, S.M.W., Crecelius, E.A., Hardy, J.T., Fellows, R.J., 1987. Acute environmental toxicity and persistence of selected chemical agent simulants: diisopropyl fluorophosphates (DFP) and diisopropyl methylphosphate (DIMP). CRCDEC-CR-87071, US Army Armament, Munitions & Chemical Command, Aberdeen, Proving Ground MD (U.S. NTIS AD-A181309), 51pp.
24. Volans A.P. Sarin: guidelines on the management of victims of a nerve gas attack. J. Accid. Emerg. Med. 13 (1996) 202-206