The effect of UGT1A1 promoter polymorphism on bilirubin response to hydroxyurea therapy in hemoglobinopathies

Clinical Biochemistry

Volumn 43, Issue 16-17, 2010, Pages 1329-1332

  Italia, Khushnooma Y ^a   Jijina, Farah F ^b   Jain, Dipty ^c   Merchant, Rashid ^d   Nadkarni, Anita H ^a   Mukherjee, Malay ^a   Ghosh, Kanjaksha ^a   Colah, Roshan B ^a  

^a NATIONAL INSTITUTE OF IMMUNOHAEMATOLOGY   (India)

^b KEM HOSPITAL   (India)

^c GOVERNMENT MEDICAL COLLEGE   (India)

^d DR BALABHAI NANAVATI HOSPITAL   (India)

Author keywords

thalassemia intermedia; HbE thalassemia; Hydroxyurea; Hyperbilirubinemia; Sickle cell anemia; UGT1A1

Indexed keywords

BILIRUBIN; GLUCURONOSYLTRANSFERASE 1A1; HYDROXYUREA;

ADOLESCENT; ADULT; ARTICLE; BETA THALASSEMIA; CHILD; DNA POLYMORPHISM; DRUG EFFECT; ERYTHROPOIESIS; GENE SEQUENCE; HEMOGLOBINOPATHY; HEMOLYSIS; HUMAN; HYPERBILIRUBINEMIA; INDIA; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROMOTER REGION; SICKLE CELL ANEMIA;

ADOLESCENT; ADULT; BILIRUBIN; CHILD; GENE DELETION; GLUCURONOSYLTRANSFERASE; HEMOGLOBINOPATHIES; HUMANS; HYDROXYUREA; POLYMORPHISM, GENETIC; PROMOTER REGIONS, GENETIC; REPETITIVE SEQUENCES, NUCLEIC ACID; YOUNG ADULT;

EID: 77957369356     PISSN: 00099120     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clinbiochem.2010.08.006     Document Type: Article

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