Axial impeller selection for anchorage dependent animal cell culture in stirred bioreactors: Methodology based on the impeller comparison at just-suspended speed of rotation

Chemical Engineering Science

Volumn 65, Issue 22, 2010, Pages 5929-5941

  Collignon, Marie Laure ^a,b   Delafosse, Angélique ^a,b   Crine, Michel ^a,b   Toye, Dominique ^a  

^a UNIVERSITY OF LIÈGE   (Belgium)

^b FNRS   (Belgium)

Author keywords

Animal cell culture; Axial impeller; Hydrodynamics; Mechanical constraints; Particle image velocimetry; Stirred tank

Indexed keywords

AGITATION CONDITIONS; ANCHORAGE-DEPENDENT CELLS; ANIMAL CELLS; AXIAL IMPELLER; CULTURE MEDIUM; INDUSTRIAL PRODUCTION; KOLMOGOROV SCALE; MECHANICAL CONSTRAINTS; MICROCARRIERS; PARTICLE IMAGE VELOCIMETRIES; POWER INPUT; PRE-SELECTED; ROTATIONAL SPEED; SEVERITY INDEX; SHEAR RATES; SPATIAL DERIVATIVES; SPEED OF ROTATION; STIRRED BIOREACTORS; STIRRED TANK; STIRRED TANK BIOREACTORS; TIME AVERAGES; TURBULENT COLLISIONS;

ANCHORAGES (FOUNDATIONS); ANIMALS; BIOREACTORS; BLOWERS; CELL CULTURE; FLOW VISUALIZATION; FLUID DYNAMICS; HYDRODYNAMICS; IMPELLERS; OSTEOBLASTS; PROPELLERS; SHEAR DEFORMATION; SPEED; VELOCIMETERS; VELOCITY MEASUREMENT;

ANIMAL CELL CULTURE;

EID: 77957358309     PISSN: 00092509     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ces.2010.08.027     Document Type: Article

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