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Volumn 177, Issue 4, 2010, Pages 2034-2045

Targeting DNA replication before it starts: Cdc7 as a therapeutic target in p53-mutant breast cancers

Author keywords

[No Author keywords available]

Indexed keywords

CELL CYCLE PROTEIN; CELL CYCLE PROTEIN CDC7; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR; MUTANT PROTEIN; PROGESTERONE RECEPTOR; PROTEIN P53; UNCLASSIFIED DRUG;

EID: 77957341219     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.2353/ajpath.2010.100421     Document Type: Article
Times cited : (45)

References (43)
  • 2
    • 77449160477 scopus 로고    scopus 로고
    • Recent advances in systemic therapy. When HER2 is not the target: Advances in the treatment of HER2-negative metastatic breast cancer
    • Miles DW: Recent advances in systemic therapy. When HER2 is not the target: advances in the treatment of HER2-negative metastatic breast cancer. Breast Cancer Res 2009, 11:208
    • (2009) Breast Cancer Res , vol.11 , pp. 208
    • Miles, D.W.1
  • 4
    • 43549109841 scopus 로고    scopus 로고
    • Targeted therapies for the treatment of breast cancer in the post-trastuzumab era
    • Petrelli F, Cabiddu M, Cazzaniga ME, Cremonesi M, Barni S: Targeted therapies for the treatment of breast cancer in the post-trastuzumab era. Oncologist 2008, 13:373-381
    • (2008) Oncologist , vol.13 , pp. 373-381
    • Petrelli, F.1    Cabiddu, M.2    Cazzaniga, M.E.3    Cremonesi, M.4    Barni, S.5
  • 5
    • 56949094800 scopus 로고    scopus 로고
    • Targeted therapies in breast cancer: Where are we now?
    • Di Cosimo S, Baselga J: Targeted therapies in breast cancer: where are we now? Eur J Cancer 2008, 44:2781-2790
    • (2008) Eur J Cancer , vol.44 , pp. 2781-2790
    • Di Cosimo, S.1    Baselga, J.2
  • 6
    • 26844559765 scopus 로고    scopus 로고
    • Trastuzumab in the treatment of breast cancer
    • Hortobagyi GN: Trastuzumab in the treatment of breast cancer. N Engl J Med 2005, 353:1734-1736
    • (2005) N Engl J Med , vol.353 , pp. 1734-1736
    • Hortobagyi, G.N.1
  • 7
    • 33748775727 scopus 로고    scopus 로고
    • Targeting downstream effectors of epidermal growth factor receptor/HER2 in breast cancer with either farnesyltransferase inhibitors or mTOR antagonists
    • Johnston SR: Targeting downstream effectors of epidermal growth factor receptor/HER2 in breast cancer with either farnesyltransferase inhibitors or mTOR antagonists. Int J Gynecol Cancer 2006, 16(Suppl 2):543-548
    • (2006) Int J Gynecol Cancer , vol.16 , Issue.SUPPL. 2 , pp. 543-548
    • Johnston, S.R.1
  • 8
    • 36749082267 scopus 로고    scopus 로고
    • Cell cycle markers in clinical oncology
    • Williams GH, Stoeber K: Cell cycle markers in clinical oncology. Curr Opin Cell Biol 2007, 19:672-679
    • (2007) Curr Opin Cell Biol , vol.19 , pp. 672-679
    • Williams, G.H.1    Stoeber, K.2
  • 10
    • 26244431903 scopus 로고    scopus 로고
    • Right place, right time, and only once: Replication initiation in metazoans
    • Machida YJ, Hamlin JL, Dutta A: Right place, right time, and only once: replication initiation in metazoans. Cell 2005, 123:13-24
    • (2005) Cell , vol.123 , pp. 13-24
    • Machida, Y.J.1    Hamlin, J.L.2    Dutta, A.3
  • 11
    • 70549085855 scopus 로고    scopus 로고
    • Eukaryotic DNA replication control: Lock and load, then fire
    • Remus D, Diffley JF: Eukaryotic DNA replication control: lock and load, then fire. Curr Opin Cell Biol 2009, 21:771-777
    • (2009) Curr Opin Cell Biol , vol.21 , pp. 771-777
    • Remus, D.1    Diffley, J.F.2
  • 12
    • 21344442139 scopus 로고    scopus 로고
    • Control of DNA replication: Regulation and activation of eukaryotic replicative helicase
    • Masai H, You Z, Arai K: Control of DNA replication: regulation and activation of eukaryotic replicative helicase. MCM IUBMB Life 2005, 57:323-335
    • (2005) MCM IUBMB Life , vol.57 , pp. 323-335
    • Masai, H.1    You, Z.2    Arai, K.3
  • 14
    • 52549115459 scopus 로고    scopus 로고
    • Replication licensing and cancer-a fatal entanglement?
    • Blow JJ, Gillespie PJ: Replication licensing and cancer-a fatal entanglement? Nat Rev Cancer 2008, 8:799-806
    • (2008) Nat Rev Cancer , vol.8 , pp. 799-806
    • Blow, J.J.1    Gillespie, P.J.2
  • 20
    • 70449185514 scopus 로고
    • Histological grading and prognosis in breast cancer; a study of 1409 cases of which 359 have been followed for 15 years
    • Bloom HJ, Richardson WW: Histological grading and prognosis in breast cancer; a study of 1409 cases of which 359 have been followed for 15 years. Br J Cancer 1957, 11:359-377
    • (1957) Br J Cancer , vol.11 , pp. 359-377
    • Bloom, H.J.1    Richardson, W.W.2
  • 21
    • 0034937342 scopus 로고    scopus 로고
    • Prognostic and predictive factors in primary breast cancer and their role in patient management: The Nottingham Breast Team
    • Rampaul RS, Pinder SE, Elston CW, Ellis IO: Prognostic and predictive factors in primary breast cancer and their role in patient management: the Nottingham Breast Team. Eur J Surg Oncol 2001, 27:229-238
    • (2001) Eur J Surg Oncol , vol.27 , pp. 229-238
    • Rampaul, R.S.1    Pinder, S.E.2    Elston, C.W.3    Ellis, I.O.4
  • 26
    • 0032896905 scopus 로고    scopus 로고
    • Estrogen receptor status by immunohistochemistry is superior to the ligand-binding assay for predicting response to adjuvant endocrine therapy in breast cancer
    • Harvey JM, Clark GM, Osborne CK, Allred DC: Estrogen receptor status by immunohistochemistry is superior to the ligand-binding assay for predicting response to adjuvant endocrine therapy in breast cancer. J Clin Oncol 1999, 17:1474-1481
    • (1999) J Clin Oncol , vol.17 , pp. 1474-1481
    • Harvey, J.M.1    Clark, G.M.2    Osborne, C.K.3    Allred, D.C.4
  • 27
    • 0032451016 scopus 로고    scopus 로고
    • 1997 ESACP consensus report on diagnostic DNA image cytometry. Part I: Basic considerations and recommendations for preparation, measurement and interpretation European Society for Analytical Cellular Pathology
    • Haroske G, Giroud F, Reith A, Bocking A: 1997 ESACP consensus report on diagnostic DNA image cytometry. Part I: basic considerations and recommendations for preparation, measurement and interpretation European Society for Analytical Cellular Pathology. Anal Cell Pathol 1998, 17:189-200
    • (1998) Anal Cell Pathol , vol.17 , pp. 189-200
    • Haroske, G.1    Giroud, F.2    Reith, A.3    Bocking, A.4
  • 30
    • 34547902426 scopus 로고    scopus 로고
    • The intra-S-phase checkpoint affects both DNA replication initiation and elongation: Singlecell and -DNA fiber analyses
    • Seiler JA, Conti C, Syed A, Aladjem MI, Pommier Y: The intra-S-phase checkpoint affects both DNA replication initiation and elongation: singlecell and -DNA fiber analyses. Mol Cell Biol 2007, 27:5806-5818
    • (2007) Mol Cell Biol , vol.27 , pp. 5806-5818
    • Seiler, J.A.1    Conti, C.2    Syed, A.3    Aladjem, M.I.4    Pommier, Y.5
  • 31
    • 23944434493 scopus 로고    scopus 로고
    • Repression of DNA replication licensing in quiescence is independent of geminin and may define the cell cycle state of progenitor cells
    • Kingsbury SR, Loddo M, Fanshawe T, Obermann EC, Prevost AT, Stoeber K, Williams GH: Repression of DNA replication licensing in quiescence is independent of geminin and may define the cell cycle state of progenitor cells. Exp Cell Res 2005, 309:56-67
    • (2005) Exp Cell Res , vol.309 , pp. 56-67
    • Kingsbury, S.R.1    Loddo, M.2    Fanshawe, T.3    Obermann, E.C.4    Prevost, A.T.5    Stoeber, K.6    Williams, G.H.7
  • 36
    • 0031019197 scopus 로고    scopus 로고
    • Cyclin D1/Cdk4 regulates retinoblastoma protein-mediated cell cycle arrest by site-specific phosphorylation
    • Connell-Crowley L, Harper JW, Goodrich DW: Cyclin D1/Cdk4 regulates retinoblastoma protein-mediated cell cycle arrest by site-specific phosphorylation. Mol Biol Cell 1997, 8:287-301
    • (1997) Mol Biol Cell , vol.8 , pp. 287-301
    • Connell-Crowley, L.1    Harper, J.W.2    Goodrich, D.W.3
  • 40
    • 24944505221 scopus 로고    scopus 로고
    • Premalignant and in situ breast disease: Biology and clinical implications
    • Arpino G, Laucirica R, Elledge RM: Premalignant and in situ breast disease: biology and clinical implications. Ann Intern Med 2005, 143:446-457
    • (2005) Ann Intern Med , vol.143 , pp. 446-457
    • Arpino, G.1    Laucirica, R.2    Elledge, R.M.3
  • 41
  • 43
    • 43049117148 scopus 로고    scopus 로고
    • The molecular journey from ductal carcinoma in situ to invasive breast cancer
    • Wiechmann L, Kuerer HM: The molecular journey from ductal carcinoma in situ to invasive breast cancer. Cancer 2008, 112:2130-2142
    • (2008) Cancer , vol.112 , pp. 2130-2142
    • Wiechmann, L.1    Kuerer, H.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.