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Volumn 34, Issue 9, 2010, Pages 907-909

Addressing the design of in vitro models for the investigation of microcystins: The essential role of transporter-mediated uptake

Author keywords

In vitro models; Microcystin; Organic anion transporting polypeptide (ONTP); Transporter mediated uptake

Indexed keywords

DRINKING WATER; MICROCYSTIN; ORGANIC ANION TRANSPORTER; ORGANIC ANION TRANSPORTER 1A2; ORGANIC ANION TRANSPORTER 1B1; ORGANIC ANION TRANSPORTER 1B3; UNCLASSIFIED DRUG;

EID: 77957340057     PISSN: 10656995     EISSN: 10958355     Source Type: Journal    
DOI: 10.1042/CBI20100244     Document Type: Article
Times cited : (5)

References (13)
  • 1
    • 29244445465 scopus 로고    scopus 로고
    • Microcystin-LR induced cellular effects in mammalian and fish primary hepatocyte cultures and cell lines: a comparative study
    • Boaru DA, Dragos N and Schirmer K. Microcystin-LR induced cellular effects in mammalian and fish primary hepatocyte cultures and cell lines: a comparative study. Toxicology 2006;218:134-48.
    • (2006) Toxicology , vol.218 , pp. 134-148
    • Boaru, D.A.1    Dragos, N.2    Schirmer, K.3
  • 2
    • 0010416233 scopus 로고    scopus 로고
    • Analysis of Microcystins involved in an outbreak of liver failure and death of humans at a haemodialysis center in Caruaru, Pernambuco, Brazil
    • Brazilian Society of Toxicology
    • Carmichael WW, An JS, Azevedo SMFO, Lau S. Analysis of Microcystins involved in an outbreak of liver failure and death of humans at a haemodialysis center in Caruaru, Pernambuco, Brazil. Proceedings of IV symposium of the Brazilian Society of Toxicology; Brazil. Brazilian Society of Toxicology 1996;83.
    • (1996) Proceedings of IV symposium of the Brazilian Society of Toxicology: Brazil , pp. 83
    • Carmichael, W.W.1    An, J.S.2    Azevedo, S.M.F.O.3    Lau, S.4
  • 3
    • 77952498953 scopus 로고    scopus 로고
    • Abrogation of microcystin cytotoxicity by MAP kinase inhibitors and N-acetyl cysteine is confounded by OATPIB1 uptake activity inhibition
    • Daily A, Monks NR, Leggas M and Moscow JA. Abrogation of microcystin cytotoxicity by MAP kinase inhibitors and N-acetyl cysteine is confounded by OATPIB1 uptake activity inhibition. Toxicon 2010;55:827-37.
    • (2010) Toxicon , vol.55 , pp. 827-837
    • Daily, A.1    Monks, N.R.2    Leggas, M.3    Moscow, J.A.4
  • 5
    • 58149260266 scopus 로고    scopus 로고
    • Oatp-associated uptake and toxicity of microcystins in primary murine whole brain cells
    • Feurstein D, Holst K, Fischer A and Dietrich DR. Oatp-associated uptake and toxicity of microcystins in primary murine whole brain cells. Toxicol Appl Pharmacol 2009;234:247-55.
    • (2009) Toxicol Appl Pharmacol , vol.234 , pp. 247-255
    • Feurstein, D.1    Holst, K.2    Fischer, A.3    Dietrich, D.R.4
  • 6
    • 0037427972 scopus 로고    scopus 로고
    • The superfamily of organic anion transporting polypeptides
    • Hagenbuch B and Meier PJ. The superfamily of organic anion transporting polypeptides. Biochim Biophys Acta 2003;1609: 1-18.
    • (2003) Biochim Biophys Acta , vol.1609 , pp. 1-18
    • Hagenbuch, B.1    Meier, P.J.2
  • 9
    • 70350536286 scopus 로고    scopus 로고
    • Microcystins in groundwater wells and their accumulation in vegetable plants irrigated with contaminated waters in Saudi Arabia
    • Mohamed ZA, Al Shehri AM. Microcystins in groundwater wells and their accumulation in vegetable plants irrigated with contaminated waters in Saudi Arabia. J Hazard Mater 2009;172:310-5.
    • (2009) J Hazard Mater , vol.172 , pp. 310-315
    • Mohamed, Z.A.1    Al Shehri, A.M.2
  • 10
    • 33847411960 scopus 로고    scopus 로고
    • Potent cytotoxicity of the phosphatase inhibitor microcystin LR and microcystin analogues in OATP1B1-and OATP1B3-expressing HeLa cells
    • Monks NR, Liu S, Xu Y, Yu H, Bendelow AS, Moscow JA. Potent cytotoxicity of the phosphatase inhibitor microcystin LR and microcystin analogues in OATP1B1-and OATP1B3-expressing HeLa cells. Mol Cancer Ther 2007;6:587-98.
    • (2007) Mol Cancer Ther , vol.6 , pp. 587-598
    • Monks, N.R.1    Liu, S.2    Xu, Y.3    Yu, H.4    Bendelow, A.S.5    Moscow, J.A.6
  • 12
    • 24344491167 scopus 로고    scopus 로고
    • Detection of microcystin synthetase genes in health food supplements containing the freshwater cyanobacterium Aphanizomenon flos-aquae
    • Saker ML, Jungblut AD, Neilan BA, Rawn DF, Vasconcelos VM. Detection of microcystin synthetase genes in health food supplements containing the freshwater cyanobacterium Aphanizomenon flos-aquae. Toxicon 2005;46:555-62.
    • (2005) Toxicon , vol.46 , pp. 555-562
    • Saker, M.L.1    Jungblut, A.D.2    Neilan, B.A.3    Rawn, D.F.4    Vasconcelos, V.M.5
  • 13
    • 33746787082 scopus 로고    scopus 로고
    • World Health Organisation. WHO guideline for drinking-water quality. Geneva: WHO
    • World Health Organisation. Cyanobacterial toxins: microcystin-LR in drinking-water. WHO guideline for drinking-water quality. Geneva: WHO 2003.
    • (2003) Cyanobacterial toxins: microcystin-LR in drinking-water


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.