Hemorheology and exercise: effects of warm environments and potential consequences for sickle cell trait carriers

Scandinavian Journal of Medicine and Science in Sports

Volumn 20, Issue SUPPL. 3, 2010, Pages 48-52

  Connes, Philippe ^a  

^a UNIVERSITÉ DES ANTILLES ET DE LA GUYANE   (France)

Author keywords

Aggregation; Blood viscosity; Cycling; Deformability; Hemoglobinopathy; Running; Thermal loading

Indexed keywords

EID: 77957337687     PISSN: 09057188     EISSN: 16000838     Source Type: Journal    
DOI: 10.1111/j.1600-0838.2010.01208.x     Document Type: Review

References (29)

1. Baskurt OK, Meiselman HJ. In vivo hemorheology. Handbook of hemorheology and hemodynamics 2007, 322-338. Baskurt OK, Hardeman PRRampling MWMeiselman HJ. eds, IOS Press, Amsterdam, The Netherlands
2. Baskurt OK, Meiselman HJ. RBC aggregation: more important than RBC adhesion to endothelial cells as a determinant of in vivo blood flow in health and disease. Microcirculation 2008, 15:585-590.
3. Baskurt OK, Yalcin O, Ozdem S, Armstrong JK, Meiselman HJ. Modulation of endothelial nitric oxide synthase expression by red blood cell aggregation. Am J Physiol Heart Circ Physiol 2004, 286:H222-H229.
4. Brun JF, Connes P, Varlet-Marie E. Alterations of blood rheology during and after exercise are both consequences and modifiers of body's adaptation to muscular activity. Sci Sports 2007, 22:251-266.
5. Brun JF, Fons C, Supparo C, Mallard C, Orsetti A. Could exercise-induced increase in blood viscosity at high shear rate be entirely explained by hematocrit and plasma viscosity changes? Clin Hemorheol 1993, 13((2)):187-199.
6. Brun JF, Khaled S, Raynaud E, Bouix D, Micallef JP, Orsetti A. The triphasic effects of exercise on blood rheology: which relevance to physiology and pathophysiology? Clin Hemorheol Microcirc 1998, 19:89-104.
7. Connes P. Elevated blood viscosity during exercise: what are the consequences? Clin Hemorheol Microcirc 2009b, 42:303-304.
8. Connes P, Bouix D, Durand F, Kippelen P, Mercier J, Prefaut C, Brun JF, Caillaud C. Is hemoglobin desaturation related to blood viscosity in athletes during exercise? Int J Sports Med 2004, 25:569-574.
9. Connes P, Hardy-Dessources MD, Hue O. Counterpoint: sickle cell trait should not be considered asymptomatic and as a benign condition during physical activity. J Appl Physiol 2007, 103:2138-2140. discussion 2140-2141
10. Connes P, Tripette J, Mukisi-Mukaza M, Baskurt OK, Toth K, Meiselman HJ, Hue O, Antoine-Jonville S. Relationships between hemodynamic, hemorheological and metabolic responses during exercise. Biorheology 2009a, 46:133-143.
11. Driessen GK, Haest CW, Heidtmann H, Kamp D, Schmid-Schonbein H. Effect of reduced red cell "deformability" on flow velocity in capillaries of rat mesentery. Pflugers Arch 1980, 388:75-78.
12. El-Sayed MS, Omar AA. Does ambient temperature affect exercise-induced changes of the main determinants of blood rheology? (abstract). Biorheology 2008, 1,2:176-177.
13. Ernst E, Daburger L, Saradeth T. The kinetics of blood rheology during and after prolonged standardized exercise. Clin Hemorheol 1991, 11:429-439.
14. Galea G, Davidson RJ. Hemorrheology of marathon running. Int J Sports Med 1985, 6:136-138.
15. Hedreville M, Connes P, Romana M, Magnaval G, David T, Hardy-Dessources MD, Belloy MS, Etienne-Julan M, Hue O. Central retinal vein occlusion in a sickle cell trait carrier after a cycling Race. Med Sci Sports Exerc 2009, 41:14-18.
16. Kareva JV, Gushchin AG. Influence of thermal loading of different duration on hemorheological parameters. June 12-15, Yaroslav, Russia, 2009
17. Kark JA, Ward FT. Exercise and hemoglobin S. Semin Hematol 1994, 31:181-225.
18. Kaul DK, Koshkaryev A, Artmann G, Barshtein G, Yedgar S. Additive effect of red blood cell rigidity and adherence to endothelial cells in inducing vascular resistance. Am J Physiol Heart Circ Physiol 2008, 295:H1788-H1793.
19. Neuhaus D, Behn C, Gaehtgens P. Haemorheology and exercise: intrinsic flow properties of blood in marathon running. Int J Sports Med 1992, 13:506-511.
20. Neuhaus D, Gaehtgens P. Haemorrheology and long term exercise. Sports Med 1994, 18:10-21.
21. Oostenbrug GS, Mensink RP, Hardeman MR, De Vries T, Brouns F, Hornstra G. Exercise performance, red blood cell deformability, and lipid peroxidation: effects of fish oil and vitamin E. J Appl Physiol 1997, 83:746-752.
22. Parthasarathi K, Lipowsky HH. Capillary recruitment in response to tissue hypoxia and its dependence on red blood cell deformability. Am J Physiol 1999, 277:H2145-H2157.
23. Poiseuille JLM. Recherches sur les causes du mouvement du sang dans les vaisseaux capillaires. C R Acad Sci Paris 1835, 1:554-560.
24. Reinhart WH, Stäubli M, Straub W. Impaired red cell filterability with elimination of old red blood cells during a 100-km race. J Appl Physiol 1983, 54:827-830.
25. Salazar Vazquez BY, Wettstein R, Cabrales P, Tsai AG, Intaglietta M. Microvascular experimental evidence on the relative significance of restoring oxygen carrying capacity vs. blood viscosity in shock resuscitation. Biochim Biophys Acta 2008, 1784:1421-1427.
26. Senay LC, Pivarnik JM. Fluid shifts during exercise. Exerc Sport Sci Rev 1985, 13:335-387.
27. Tripette J, Loko G, Samb A, Doubi BG, Sewade E, Seck D, Hue O, Romana M, Diop S, Diaw M, Brudey K, Bogui P, Cisse F, Hardy-Dessources MD, Connes P. Effects of hydration and dehydration on blood rheology in sickle cell trait carriers during exercise. Am J Physiol (Heart Circ Physiol) 2010
28. Tsai AG, Acero C, Nance PR, Cabrales P, Frangos JA, Buerk DG, Intaglietta M. Elevated plasma viscosity in extreme hemodilution increases perivascular nitric oxide concentration and microvascular perfusion. Am J Physiol Heart Circ Physiol 2005, 288:H1730-H1739.
29. Wood SC, Doyle MP, Appenzeller O. Effects of endurance training and long distance running on blood viscosity. Med Sci Sports Exerc 1991, 3:1265-1269.