Nitrogen-containing bisphosphonate, YM529/ONO-5920, inhibits tumor metastasis in mouse melanoma through suppression of the Rho/ROCK pathway

Clinical and Experimental Metastasis

Volumn 27, Issue 7, 2010, Pages 529-538

  Tanimori, Yoshihiro ^a,b   Tsubaki, Masanobu ^a   Yamazoe, Yuzuru ^a,b   Satou, Takao ^c   Itoh, Tatsuki ^c   Kidera, Yasuhiro ^a,b   Yanae, Masahi ^a,c   Yamamoto, Chikako ^a   Kaneko, Junichi ^a   Nishida, Shozo ^a  

^a KINKI UNIVERSITY   (Japan)

^b KINDAI UNIVERSITY HOSPITAL   (Japan)

^c KINKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Adhesion; Bisphosphonate; Invasion; Metastasis; Migration; MMP; Rho

Indexed keywords

BISPHOSPHONIC ACID DERIVATIVE; GUANOSINE TRIPHOSPHATASE; MATRIX METALLOPROTEINASE; MEVALONIC ACID; MINODRONIC ACID; NITROGEN; RAS PROTEIN; RHO FACTOR; IMIDAZOLE DERIVATIVE; PRIMER DNA; RHO KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CELL ADHESION; CELL INVASION; CONTROLLED STUDY; CYTOTOXICITY; DRUG INHIBITION; LUNG METASTASIS; MALE; MELANOMA; METASTASIS INHIBITION; MIGRATION INHIBITION; MOUSE; NONHUMAN; PRENYLATION; ANIMAL; C57BL MOUSE; EXPERIMENTAL MELANOMA; FEMALE; METABOLISM; METASTASIS; NUCLEOTIDE SEQUENCE; PATHOLOGY; POLYMERASE CHAIN REACTION; TUMOR CELL LINE; WESTERN BLOTTING;

ANIMALS; BASE SEQUENCE; BLOTTING, WESTERN; CELL LINE, TUMOR; DIPHOSPHONATES; DNA PRIMERS; FEMALE; IMIDAZOLES; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL; NEOPLASM METASTASIS; POLYMERASE CHAIN REACTION; RHO-ASSOCIATED KINASES;

EID: 77957332433     PISSN: 02620898     EISSN: 15737276     Source Type: Journal    
DOI: 10.1007/s10585-010-9342-z     Document Type: Article

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