Composition, antimicrobial activity and in vitro cytotoxicity of essential oil from Cinnamomum zeylanicum Blume (Lauraceae)

Food and Chemical Toxicology

Volumn 48, Issue 11, 2010, Pages 3274-3280

  Unlu, Mehmet ^a   Ergene, Emel ^b   Unlu, Gulhan Vardar ^a   Zeytinoglu, Hulya Sivas ^b   Vural, Nilufer ^c  

^a CUMHURIYET UNIVERSITY   (Turkey)

^b ANADOLU UNIVERSITY   (Turkey)

^c ANKARA UNIVERSITY   (Turkey)

Author keywords

Antimicrobial activity; Apoptosis; Cinnamomum zeylanicum; Cytotoxicity; Essential oil

Indexed keywords

ACRIDINE ORANGE; AMIKACIN; BENZALDEHYDE; CINEOLE; CINNAMALDEHYDE; CINNAMIC ACID; CINNAMYL ACETATE; CIPROFLOXACIN; CLINDAMYCIN; ESSENTIAL OIL; ETHIDIUM BROMIDE; EUGENOL; FLUCONAZOLE; LIMONENE; LINALOOL; PINENE; RAS PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIBACTERIAL ACTIVITY; ANTIBIOTIC SENSITIVITY; ANTIFUNGAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BARK; CANDIDA; CELL STRUCTURE; CHEMICAL COMPOSITION; CINNAMOMUM ZEYLANICUM; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFICACY; DRUG POTENCY; EMBRYO; FIBROBLAST; IC 50; IN VITRO STUDY; MASS FRAGMENTOGRAPHY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; RAT;

ACROLEIN; ANIMALS; ANTI-BACTERIAL AGENTS; ANTICARCINOGENIC AGENTS; APOPTOSIS; BENZALDEHYDES; CELL LINE; CELL SURVIVAL; CINNAMATES; CINNAMOMUM ZEYLANICUM; FIBROBLASTS; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; MICROBIAL SENSITIVITY TESTS; OILS, VOLATILE; PLANT BARK; PLANT OILS; RATS; TETRAZOLIUM SALTS; THIAZOLES;

BACTERIA (MICROORGANISMS); CANDIDA; CINNAMOMUM VERUM; LAURACEAE;

EID: 77957331032     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2010.09.001     Document Type: Article

References (53)

1. Adams R.P. Identification of essential oil components by gas chromatography/quadrupole mass spectroscopy 2001, Allured Publishing Corp, Carol Stream, IL.
2. Bakkali F., Averbeck S., Averbeck D. Biological effects of essential oils - a review. Food Chem. Toxicol. 2008, 46:446-475.
3. Bakkali F., Averbeck S., Averbeck D., Zhiri A., Baudoux D., Idaomar M. Antigenotoxic effects of three essential oils in diploid yeast (Saccharomyces cerevisiae) after treatments with UVC radiation, 8-MOP plus UVA and MMS. Mutat. Res. 2006, 606:27-38.
4. Baratta M.T., Dorman H.J.D., Deans S.G., Figueiredo A.C., Barroso J.G., Ruberto G. Antimicrobial and antioxidant properties of some commercial essential oils. Flavour Frag. J. 1998, 13(4):235-244.
5. Baytop, T., 1999. Türkiye'de Bitkiler ile Tedavi (Treatment with Plants in Turkey). Istanbul University Publications, No: 3255/40, Istanbul, Turkey.
6. Bezivin C., Tomasi S., Lohezic-Le Devehat F., Boustie C. Cytotoxic activity of some lichen extracts on murine and human cancer cell lines. Phytomedicine 2003, 10:499-503.
7. Bin Jantan I., Moharam B.A.K., Santhanam J., Jamal J.A. Correlation between chemical composition and antifungal activity of the essential oils of eight Cinnamomum species. Pharm. Biol. 2008, 46(6):406-412.
8. Burt S. Essential oils: their antibacterial properties and potential applications in foods - a review. Int. J. Food Microbiol. 2004, 94(3):223-253.
9. Carmo E.S., Lima E.D., de Souza E.L., de Sousa F.B. Effect of Cinnamomum zeylanicum blume essential oil on the growth and morphogenesis of some potentially pathogenic Aspergillus species. Braz. J. Microbiol. 2008, 39(1):91-97.
10. Carnesecchi S., Bras-Gonçalves R., Bradaia A., Zeisel M., Gosse F., Poupon M.F., Raul F. Graniol, a component of plant essential oil, modulates DNA synthesis and potentiates 5-fluorouracil efficacy on human colon tumor xenografts. Cancer Lett. 2004, 215:53-59.
11. Chang C.W., Chang W.L., Chang S.T., Cheng S.S. Antibacterial activities of plant essential oils against Legionella pneumophila. Water Res. 2008, 42:278-286.
12. Chao S.C., Young D.G., Oberg C.J. Screening for inhibitory activity of essential oils on selected bacteria, fungi and viruses. J. Essent. Oil Res. 2000, 12(5):639-649.
13. Chen C.Y., Liu T.Z., Chen C.H., Wu C.C., Cheng J.T., Yiin S.J., Shih M.K., Wu M.J., Chern C.L. Isoobtusilactone A-induced apoptosis in human hepatoma Hep G2cells is mediated via increased NADPH oxidase-derived reactive oxygen species (ROS) production and the mitochondria-associated apoptotic mechanisms. Food Chem. Toxicol. 2007, 45:1268-1276.
14. Cheng S.S., Liu J.Y., Hsui Y.R., Chang S.T. Chemical polymorphism and antifungal activity of essential oils from leaves of different provenances of indigenous cinnamon (Cinnamomum osmophloeum). Bioresource. Technol. 2006, 97:306-312.
15. Crowell P.L. Prevention and therapy of cancer by dietary monoterpenes. J. Nutr. 1999, 129(3):775S-778S.
16. Di Pasqua R., Betts G., Hoskins N., Edwards M., Ercolini D., Mauriello G. Membrane toxicity of antimicrobial compounds from essential oils. J. Agr. Food Chem. 2007, 55(12):4863-4870.
17. Domarachy M., Rehak P., Juhas S., Koppel J. Effects of selected plant essential oils on the growth and development of mouse preimplantation embryos in vivo. Physiol. Res. 2007, 56:97-104.
18. Dusan F., Marian S., Katarina D., Dobroslava B. Essential oils-their antimicrobial activity against Escherichia coli and effect on intestinal cell viability. Toxicol. In Vitro 2006, 20:1435-1445.
19. Fichi G., Flamini G., Zaralli L.J., Perrucci S. Efficacy of an essential oil of Cinnamomum zeylanicum against Psoroptes cuniculi. Phytomedicine 2007, 14:227-231.
20. Franz, C., Baser, K., Windisch, W., 2009. Essential oils and aromatic plants in animal feeding - a European perspective. Flavour and Fragrance Journal n/a. doi:10.1002/ffj.1967.
21. Friedman M., Henika P.R., Mandrell R.E. Bactericidal activities of plant essential oils and some of their isolated constituents against Campylobacter jejuni, Escherichia coli, Listeria monocytogenes and Salmonella enterica. J. Food Protect. 2002, 65(10):1545-1560.
22. Gelb M.H., Tamanoil F., Yokoyama K., Ghomashchi F., Esson K., Gould M.N. The inhibition of protein prenyltransferases by oxygenated metabolites of limonene and perillyl alcohol. Cancer Lett. 1995, 91:169-175.
23. Gogvadze V., Orrenius S., Zhivotovsky B. Multiple pathways of cytochrome c release from mitochondria in apoptosis. BBA - Bioenergetics 2006, 1757(5-6):639-647.
24. Gould M.N., Moore C.J., Zhang R., Wang B., Kennan W.S., Haag J.D. Limonene chemoprevention of mammary carcinoma induction following direct in situ transfer of v-Ha-ras. Cancer Res. 1994, 54:3540-3543.
25. Helander I.M., Alakomi H.L., Latva-Kala K., Mattila-Sandholm T., Pol I., Smid E.J., Gorris L.G.M., von Wright A. Characterization of the action of selected essential oil components on gram-negative bacteria. J. Agr. Food Chem. 1998, 46(9):3590-3595.
26. Ho S.C., Tsai T.H., Tsai P.J., Lin C.C. Protective capacities of certain spices against peroxynitrite-mediated biomolecular damage. Food Chem. Toxicol. 2008, 46:920-928.
27. Huang T.C., Fu H.Y., Ho C.T., Tan D., Huang Y.T., Pan M.H. Induction of apoptosis by cinnamaldehyde from indigenous cinnamon Cinnamomum osmophloeum Kaneh through reactive oxygen species production, glutathione depletion, and caspase activation in human leukemia K562 cells. Food Chem. 2007, 103:434-443.
28. Jayaprakasha G.K., Negi P.S., Jena B.S., Jagan Mohan Rao L. Antioxidant and antimutajenic activities of Cinnamomum zeylanicum fruit extracts. J. Food Compos. Anal. 2007, 20:330-336.
29. Johnson E.M., Richardson M.D., Warnock D.W. In vitro resistance to imidazole antifungals in Candida albicans. J. Antimicrob. Chemoth. 1984, 13:547-558.
30. Kaa H., Parkb H.J., Jungb H.J., Choic J.W., Chod K.S., Had J., Leea K.T. Cinnamaldehyde induces apoptosis by ROS-mediated mitochondrial permeability transition in human promyelocytic leukemia HL-60 cells. Cancer Lett. 2003, 196:143-152.
31. Kalemba D., Kunicka A. Antibacterial and antifungal properties of essential oils. Curr. Med. Chem. 2003, 10:813-829.
32. Kaufmann S.H. Induction of endonucleolytic DNA cleavage in human acute myelogenous leukemia cells by etoposide, camptothecin, and other cytotoxic anticancer drugs: a cautionary note. Cancer Res. 1989, 49:5870-5878.
33. Lee H.S., Kim S.Y., Lee C.H., Ahn Y.J. Cytotoxic and mutagenic effects of Cinnamomum cassia bark-derived materials. J. Microbiol. Biotechnol. 2004, 14(6):1176-1181.
34. Marongiu B., Piras A., Porcedda S., Tuveri E., Sanjust E., Meli M., Sollai F., Zucca P., Rescigno A. Supercritical CO2 extract of Cinnamomum zeylanicum: Chemical characterization and antityrosinase activity. J. Agr. Food Chem. 2007, 55(24):10022-10027.
35. Marshall C.J. How does p21 ras transform cells?. Trends Genet. 1991, 7(3):91-95.
36. Moon E.Y., Lee M.R., Wang A.G., Lee J.H., Kim H.C., Kim H.M., Kim J.M., Kwon B.M., Yu D.Y. Delayed occurrence of H-ras12V-induced hepatocellular carcinoma with long-term treatment with cinnamaldehydes. Eur. J. Pharmacol. 2006, 530:270-275.
37. NCCLS (National Committee for Clinical Laboratory Standards), 1997. Performance Standards for Antimicrobial Disk Susceptibility Test, sixth ed. Approved Standard, M2-A6, Wayne, PA.
38. NCCLS (National Committee for Clinical Laboratory Standards), 1999. Performance Standards for Antimicrobial Susceptibility Testing, ninth International Supplement, M100-S9, Wayne, PA.
39. NCCLS (National Committee for Clinical Laboratory Standards), 2003. Method for Antifungal Disk Diffusion Susceptibility Testing of Yeasts. Proposed Guideline NCCLS Document M44-P National Committee for Clinical and Laboratory Standards, Wayne, PA.
40. Ooi L.S.M., Li Y.L., Kam S.L., Wang H., Wong E.Y.L., Ooi V.E.C. Antimicrobial activities of cinnamon oil and cinnamaldehyde from the Chinese medicinal herb Cinnamomum cassia Blume. Am. J. Chin. Med. 2006, 34(3):51-522.
41. Oussalah M., Caillet S., Saucier L., Lacroix M. Inhibitory effects of selected plant essential oils on the growth of four pathogenic bacteria: E. coli O157:H7, Salmonella typhimurium, Staphylococcus aureus and Listeria monocytogenes. Food Control 2007, 18:414-420.
42. Ranasinghe L., Jayawardena B., Abeywickrama K. Fungicidal activity of essential oils of Cinnamomum zeylanicum (L.) and Syzygium aromaticum (L.) Merr et L.M. Perry against crown rot and anthracnose pathogens isolated from banana. Lett. Appl. Microbiol. 2002, 35:208-221.
43. Shahverdi A.R., Monsef-Esfahani H.R., Tavasoli F., Zaheri A., Mirjani R. Trans-cinnamaldehyde from Cinnamomum zeylanicum bark essential oil reduces the clindamycin resistance of Clostridium difficile in vitro. J. Food Sci. 2007, 72(1):S55-S58.
44. Shan B., Cai Y.Z., Brooks J.D., Corke H. Antibacterial properties and major bioactive components of cinnamon stick (Cinnamomum burmannii): Activity against foodborne pathogenic bacteria. J. Agr. Food Chem. 2007, 55(14):5484-5490.
45. Simiç A., Sokoviç M.D., Ristiç M., Grujiç-Jovanoviç S., Vukojeviç J., Marin P.D. The chemical composition of some Lauraceae essential oils and their antifungal activities. Phytother. Res. 2004, 18:713-717.
46. Stammati A., Bonsi P., Zucco F., Moezelaar R., Alakomi H.-L., von Wright A. Toxicity of selected plant volatiles in microbial and mammalian short-term assays. Food Chem. Toxicol. 1999, 37:813-823.
47. Testore G.P., Dori L., Buonomini A.R., Schito G.C., Soro O., Fortina G., Andreoni S., Carlone N., Tullio V., Andreoni M. In vitro fluconazole susceptibility of 1565 clinical isolates of Candida species evaluated by the disk diffusion method performed using NCCLS M44-A guidelines. Diagn. Micr. Infect. Dis. 2004, 50:187-192.
48. Tsuji-Naito K. Aldehytic components of Cinnamon bark extract suppresses RANKL-induced osteoclastogenesis through NFATc1 downregulation. Bioorg. Med. Chem. 2008, 16:9176-9183.
49. Tung Y.T., Chua M.T., Wang S.Y., Chang S.T. Anti-inflammation activities of essential oil and its constituents from indigenous cinnamon (Cinnamomum osmophloeum) twigs. Bioresour. Technol. 2008, 99:3908-3913.
50. Yang Y.C., Lee H.S., Lee S.H., Clark J.M., Ahn Y.J. Ovicidal and adulticidal activities of Cinnamomum zeylanicum bark essential oil compounds and related compounds against Pediculus humanus capitis (Anoplura: Pediculicidae). Int. J. Parasitol. 2005, 35(14):1595-1600.
51. Xiao J.X., Huang G.Q., Zhu C.P., Ren D.D., Zhang S.H. Morphological study on apoptosis Hela cells induces by soyasaponins. Toxicol. In Vitro 2007, 21:820-826.
52. Zeytinoglu H., Incesu Z., Ayaz Tuylu B., Turk Ozdemir A., Barutca B. Determination of genotoxic Antigenotoxic and cytotoxic potential of the extract from Lichen Cetraria aculeata (Schreb.) Fr. in vitro. Phytother. Res. 2008, 22:118-123.
53. Zeytinoglu H., Incesu Z., Baser K.H.C. Inhibition of DNA synthesis by carvacrol in mouse myoblast cells bearing a human N-ras oncogene. Phytomedicine 2003, 10(4):292-299.